Single-cell transcriptome atlas of spontaneous dry age-related macular degeneration in macaques

[1]  Colby F Lewallen,et al.  Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG , 2022, International journal of molecular sciences.

[2]  Haibo Wang,et al.  Regulation of Rac1 Activation in Choroidal Endothelial Cells: Insights into Mechanisms in Age-Related Macular Degeneration , 2021, Cells.

[3]  B. Birnir,et al.  Monoallelic and bi-allelic variants in NCDN cause neurodevelopmental delay, intellectual disability, and epilepsy , 2021, American journal of human genetics.

[4]  Pete A. Williams,et al.  Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice , 2020, Journal of Neuroinflammation.

[5]  F. Tang,et al.  Deciphering primate retinal aging at single-cell resolution , 2020, Protein & Cell.

[6]  D. Sacks,et al.  IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation , 2020, Angiogenesis.

[7]  K. Green,et al.  To Kill a Microglia: A Case for CSF1R Inhibitors. , 2020, Trends in immunology.

[8]  Xiaoqun Wang,et al.  A single-cell transcriptome atlas of the aging human and macaque retina , 2020, bioRxiv.

[9]  Brian R. Kotajarvi,et al.  The senescence-associated secretome as an indicator of age and medical risk. , 2020, JCI insight.

[10]  H. Kettenmann,et al.  The VGF-derived Peptide TLQP21 Impairs Purinergic Control of Chemotaxis and Phagocytosis in Mouse Microglia , 2020, The Journal of Neuroscience.

[11]  Huafu Chen,et al.  IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis , 2020, Science Advances.

[12]  E. Schadt,et al.  VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice , 2020, Molecular Neurodegeneration.

[13]  Todd E. Scheetz,et al.  Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration , 2019, Proceedings of the National Academy of Sciences.

[14]  A. Regev,et al.  Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina , 2018, Cell.

[15]  W. Wong,et al.  Microglia in the Retina: Roles in Development, Maturity, and Disease. , 2018, Annual review of vision science.

[16]  P. Mitchell,et al.  Age-related macular degeneration , 2018, The Lancet.

[17]  B. Taylor,et al.  Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling , 2017, Glia.

[18]  N. Steinmetz,et al.  Viral nanoparticles decorated with novel EGFL7 ligands enable intravital imaging of tumor neovasculature. , 2017, Nanoscale.

[19]  Sina Farsiu,et al.  In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques , 2017, Scientific Reports.

[20]  B. Spittau,et al.  Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases , 2017, Front. Aging Neurosci..

[21]  M. Korte,et al.  APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission , 2017, The Journal of Neuroscience.

[22]  W. Le,et al.  Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases , 2016, Molecular Neurobiology.

[23]  U. Schraermeyer,et al.  Iron accumulation in Bruch's membrane and melanosomes of donor eyes with age-related macular degeneration. , 2015, Experimental eye research.

[24]  A. Grzybowski,et al.  Age-Related Macular Degeneration in the Aspect of Chronic Low-Grade Inflammation (Pathophysiological ParaInflammation) , 2014, Mediators of inflammation.

[25]  D. Goldman Müller glial cell reprogramming and retina regeneration , 2014, Nature Reviews Neuroscience.

[26]  D. Hyde,et al.  Regulation of Müller glial dependent neuronal regeneration in the damaged adult zebrafish retina. , 2014, Experimental eye research.

[27]  G. A. Limb,et al.  Transplantation of Photoreceptors Derived From Human Müller Glia Restore Rod Function in the P23H Rat , 2014, Stem cells translational medicine.

[28]  P. Raymond,et al.  Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish , 2014, Progress in Retinal and Eye Research.

[29]  Sina Farsiu,et al.  Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging. , 2013, Investigative ophthalmology & visual science.

[30]  Daniel Ardeljan,et al.  Aging is not a disease: Distinguishing age-related macular degeneration from aging , 2013, Progress in Retinal and Eye Research.

[31]  Qiang Wu,et al.  Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells. , 2013, Experimental eye research.

[32]  L. Zhong,et al.  Effect of GINS2 on Proliferation and Apoptosis in Leukemic Cell Line , 2013, International journal of medical sciences.

[33]  A. Minajeva,et al.  Relationship between neovascularization and degenerative changes in herniated lumbar intervertebral discs , 2013, European Spine Journal.

[34]  E. Chew,et al.  Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management. , 2012, Ophthalmology.

[35]  F. Parmeggiani,et al.  Mechanism of Inflammation in Age-Related Macular Degeneration , 2012, Mediators of inflammation.

[36]  Adam Boretsky,et al.  In vivo imaging of photoreceptor disruption associated with age‐related macular degeneration: A pilot study , 2012, Lasers in surgery and medicine.

[37]  I. Bhutto,et al.  Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex. , 2012, Molecular aspects of medicine.

[38]  J. Ambati,et al.  Mechanisms of Age-Related Macular Degeneration , 2012, Neuron.

[39]  G. A. Limb,et al.  Human Müller Glia with Stem Cell Characteristics Differentiate into Retinal Ganglion Cell (rgc) Precursors in Vitro and Partially Restore Rgc Function in Vivo following Transplantation G. Astrid Limb a Key Words. Tissue-specific Stem Cells @bullet Differentiation @bullet Cell Transplantation @bullet , 2022 .

[40]  C. Luu,et al.  Central retinal function as measured by the multifocal electroretinogram and flicker perimetry in early age-related macular degeneration. , 2011, Investigative ophthalmology & visual science.

[41]  R. Masland Cell populations of the retina: the Proctor lecture. , 2011, Investigative ophthalmology & visual science.

[42]  M. Urashima,et al.  Macular Dysfunction in Oguchi Disease with the Frequent Mutation 1147delA in the SAG Gene , 2011, Ophthalmic Research.

[43]  J. Connor,et al.  Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. , 2011, Investigative ophthalmology & visual science.

[44]  C. Nordgaard,et al.  Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration. , 2010, Investigative ophthalmology & visual science.

[45]  J. Wan,et al.  Preferential regeneration of photoreceptor from Müller glia after retinal degeneration in adult rat , 2008, Vision Research.

[46]  W. Thoreson,et al.  Neural stem cell properties of Müller glia in the mammalian retina: regulation by Notch and Wnt signaling. , 2006, Developmental biology.

[47]  R. Kageyama,et al.  Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[48]  A. Milam,et al.  Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane. , 2003, Archives of ophthalmology.

[49]  M. Tso,et al.  Reduced amplitude and delayed latency in foveal response of multifocal electroretinogram in early age related macular degeneration , 2001, The British journal of ophthalmology.

[50]  M. Lleonart,et al.  A new generation of proto-oncogenes: cold-inducible RNA binding proteins. , 2010, Biochimica et biophysica acta.

[51]  M. Daly,et al.  Variation near complement factor I is associated with risk of advanced AMD , 2009, European Journal of Human Genetics.

[52]  Russell J. Taylor,et al.  ASCL 1 reprograms mouse Müller glia into neurogenic retinal progenitors , 2022 .