Functional magnetic resonance imaging in children.

Functional magnetic resonance imaging (fMRI) allows for the noninvasive mapping of the anatomical location of disparate functional brain activities. The means for carrying out fMRI involves the use of existing MR technology coupled with a special software image acquisition program or the use of a specially designed head coil. Thus far in pediatric neurology, fMRI has assisted in the presurgical localization of critical functions and the investigation of various developmental activities. The technique of fMRI, its applications in pediatric neuroscience, and future potential are outlined in this article.

[1]  Anders M. Dale,et al.  Event-related fMRI: Past, Present, and Future , 1998 .

[2]  Y Yonekura,et al.  A rapid brain metabolic change in infants detected by fMRI , 1997, Neuroreport.

[3]  C. Jack,et al.  Use of functional magnetic resonance imaging. , 1996, Neurosurgery clinics of North America.

[4]  P. Huttenlocher Synaptic density in human frontal cortex - developmental changes and effects of aging. , 1979, Brain research.

[5]  M. Zilbovicius,et al.  Changes in regional cerebral blood flow during brain maturation in children and adolescents. , 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  Comparison of hemispheric dominance for language as identified by wada testing versus functional MRI in a pediatric population , 1996, NeuroImage.

[7]  D. Le Bihan,et al.  Noninvasive assessment of language dominance in children and adolescents with functional MRI , 1997, Neurology.

[8]  T. Loenneker,et al.  fMRI of the visual cortex in infants and children , 1996, NeuroImage.

[9]  P H Chapman,et al.  Functional magnetic resonance imaging for cortical mapping in pediatric neurosurgery. , 1995, Pediatric neurosurgery.

[10]  K. Kwong Functional magnetic resonance imaging with echo planar imaging. , 1995, Magnetic resonance quarterly.

[11]  D. Bihan,et al.  3Tesla fMRI study of language dominance in children with epilepsy : is Wada test always the gold standard ? , 1998, NeuroImage.

[12]  R. Turner,et al.  Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[13]  X. Hu,et al.  Functional MR imaging of working memory task activation in children: Preliminary findings , 1996, NeuroImage.

[14]  L. Sokoloff,et al.  An adaptation of the nitrous oxide method to the study of the cerebral circulation in children; normal values for cerebral blood flow and cerebral metabolic rate in childhood. , 1957, The Journal of clinical investigation.

[15]  Egill Rostrup,et al.  Change of visually induced cortical activation patterns during development , 1996, The Lancet.

[16]  A. Crawley,et al.  Regionalization Evidence of Sensorimotor Plasticity Pre and Post Hemispherectomy in Children with Epilepsy. FMRI and Clinical Studies. , 1998, NeuroImage.

[17]  V S Caviness,et al.  Functional MRI Localization of Language in a 9-Year-Old Child , 1996, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[18]  J. A. Frost,et al.  Determination of language dominance using functional MRI , 1996, Neurology.

[19]  Functional MR imaging in children , 1996, NeuroImage.

[20]  S. Bookheimer,et al.  fMRI of language in dyslexic and normally developing children , 1996, NeuroImage.

[21]  D. Noll,et al.  A Developmental fMRI Study of Prefrontal Organization , 1998, NeuroImage.

[22]  Jonathan D. Cohen,et al.  A Developmental Functional MRI Study of Prefrontal Activation during Performance of a Go-No-Go Task , 1997, Journal of Cognitive Neuroscience.

[23]  T. Loenneker,et al.  Reproducibility of fMRI and effects of pentobarbital sedation on cortical activation during visual stimulation , 1996, NeuroImage.

[24]  G H Glover,et al.  Functional MR imaging. Capabilities and limitations. , 1995, Neuroimaging clinics of North America.

[25]  J. B. Demb,et al.  Functional MRI measurement of language lateralization in Wada-tested patients. , 1995, Brain : a journal of neurology.

[26]  D. Weinberger,et al.  Functional Mapping of Human Sensorimotor Cortex with 3D BOLD fMRI Correlates Highly with H215O PET rCBF , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[27]  R. S. Hinks,et al.  Time course EPI of human brain function during task activation , 1992, Magnetic resonance in medicine.

[28]  M. Schöning,et al.  Age Dependence of Total Cerebral Blood Flow Volume from Childhood to Adulthood , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[29]  Douglas C. Noll,et al.  Activation of Prefrontal Cortex in Children during a Nonspatial Working Memory Task with Functional MRI , 1995, NeuroImage.

[30]  J. Mazziotta,et al.  Positron emission tomography study of human brain functional development , 1987, Annals of neurology.

[31]  Stephen M. Rao,et al.  Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging , 1997, The Journal of Neuroscience.

[32]  Ravi S. Menon,et al.  Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[33]  J W Belliveau,et al.  Location of language in the cortex: a comparison between functional MR imaging and electrocortical stimulation. , 1997, AJNR. American journal of neuroradiology.

[34]  H. Loos,et al.  Synaptogenesis in human visual cortex — evidence for synapse elimination during normal development , 1982, Neuroscience Letters.

[35]  J. Drake,et al.  Combined utility of functional MRI, cortical mapping, and frameless stereotaxy in the resection of lesions in eloquent areas of brain in children. , 1997, Pediatric neurosurgery.