Numerical Characterization of DNA Primary Sequence

In a previous paper, the authors defined a numerical characterization of DNA primary sequences. A DNA primary sequence was reduced to a few of binary sequences, based on the classifications of the four nucleic acid bases. The reduced sequences are called the characteristic sequences. For each characteristic sequence, we associated two 2×2 matrices, the elements of which are given by the frequency of occurrence of all (0,1) triplets in the characteristic sequence. In this paper, we use eigenvalues of the new matrices to characterize the biological functions of purine–pyrimidine, amino–keto groups and weak–strong H–bonds, respectively.

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