Epigenetics in asthma and COPD.
暂无分享,去创建一个
[1] F. Martinez,et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. , 2007, American journal of respiratory and critical care medicine.
[2] J. Epstein,et al. Tissue factor pathway inhibitor attenuates the progression of malignant pleural mesothelioma in nude mice. , 2012, American journal of respiratory cell and molecular biology.
[3] X. Estivill,et al. DNA hypomethylation at ALOX12 is associated with persistent wheezing in childhood. , 2012, American journal of respiratory and critical care medicine.
[4] J. Jukema,et al. Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors , 2012, Journal of cellular and molecular medicine.
[5] M. Dawson,et al. Cancer Epigenetics: From Mechanism to Therapy , 2012, Cell.
[6] J. Maksimovic,et al. Genome-scale profiling reveals a subset of genes regulated by DNA methylation that program somatic T-cell phenotypes in humans , 2012, Genes and Immunity.
[7] A. El-Osta,et al. Effects of the Histone Deacetylase Inhibitor, Trichostatin A, in a Chronic Allergic Airways Disease Model in Mice , 2012, Archivum Immunologiae et Therapiae Experimentalis.
[8] E. Bothur,et al. DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma. , 2012, The Journal of allergy and clinical immunology.
[9] S. Balasubramanian,et al. Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution , 2012, Science.
[10] Rachel L. Miller,et al. Epigenetics, Asthma, and Allergic Diseases: A Review of the Latest Advancements , 2012, Current Allergy and Asthma Reports.
[11] Robert A Philibert,et al. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers , 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[12] A. Baccarelli,et al. Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. , 2012, American journal of respiratory and critical care medicine.
[13] I. Rahman,et al. Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-κB-dependent Genes , 2012, PloS one.
[14] T. Pastinen,et al. Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines , 2012, Human Genetics.
[15] J. Maurer. Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study , 2012 .
[16] 蕭茹鈴. Glutathione S-Transferase P1基因多型性、抽菸與成人氣喘之相關 , 2012 .
[17] Kian Fan Chung,et al. Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma. , 2012, The Journal of allergy and clinical immunology.
[18] H. Kipen,et al. Respiratory health effects of air pollution: update on biomass smoke and traffic pollution. , 2012, The Journal of allergy and clinical immunology.
[19] A. El-Osta,et al. Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease , 2011, Epigenetics.
[20] I. Dávila,et al. PTGDR gene in asthma: a functional, genetic, and epigenetic study , 2011, Allergy.
[21] M. Esteller. Non-coding RNAs in human disease , 2011, Nature Reviews Genetics.
[22] Ankur Kulshreshtha,et al. Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. , 2011, The Journal of allergy and clinical immunology.
[23] Deepti Malhotra,et al. Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients. , 2011, The Journal of clinical investigation.
[24] M. Polkey,et al. Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD , 2011, Thorax.
[25] Miles Parkes,et al. Gene expression profiling of CD8+ T cells predicts prognosis in patients with Crohn disease and ulcerative colitis. , 2011, The Journal of clinical investigation.
[26] Eckart Meese,et al. Specific peripheral miRNA profiles for distinguishing lung cancer from COPD. , 2011, Lung cancer.
[27] G. Koppelman,et al. Recent advances in the epigenetics and genomics of asthma , 2011, Current opinion in allergy and clinical immunology.
[28] S. Orkin,et al. MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity , 2011, The Journal of Immunology.
[29] G. Joos,et al. Chronic Obstructive Pulmonary Disease 1 New insights into the immunology of chronic obstructive pulmonary disease , 2011 .
[30] T. Kutateladze,et al. SnapShot: Histone Readers , 2011, Cell.
[31] J. Greally,et al. Epigenetic changes in B lymphocytes associated with house dust mite allergic asthma , 2011, Epigenetics.
[32] Q. Hamid,et al. Remodeling in asthma. , 2011, The Journal of allergy and clinical immunology.
[33] R. Waterland,et al. Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes. , 2011, The Journal of allergy and clinical immunology.
[34] R. Young,et al. BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc , 2011, Cell.
[35] P. Wolters,et al. Interleukin-1β Induces Increased Transcriptional Activation of the Transforming Growth Factor-β-activating Integrin Subunit β8 through Altering Chromatin Architecture* , 2011, The Journal of Biological Chemistry.
[36] K. Ansel,et al. MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells. , 2011, Immunity.
[37] P. Lavender,et al. MicroRNAs in lung diseases , 2011, Thorax.
[38] H. Heine,et al. Increased Expression of Beta-Defensin 1 (DEFB1) in Chronic Obstructive Pulmonary Disease , 2011, PloS one.
[39] M. Sweet,et al. Histone deacetylases as regulators of inflammation and immunity. , 2011, Trends in immunology.
[40] P. Foster,et al. Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment. , 2011, The Journal of allergy and clinical immunology.
[41] Rakesh K. Kumar,et al. Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target , 2011, BMC pulmonary medicine.
[42] Ivana V. Yang,et al. Epigenetic control of gene expression in the lung. , 2011, American journal of respiratory and critical care medicine.
[43] Bernhard Korn,et al. Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. , 2011, American journal of human genetics.
[44] J. Vandesompele,et al. MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease. , 2011, American journal of respiratory and critical care medicine.
[45] C. Mendelson,et al. Epigenetic Regulation of Surfactant Protein A Gene (SP-A) Expression in Fetal Lung Reveals a Critical Role for Suv39h Methyltransferases during Development and Hypoxia , 2011, Molecular and Cellular Biology.
[46] S. Biswal,et al. Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress , 2011, Biochemical and biophysical research communications.
[47] I. Adcock,et al. COPD pathology in the small airways. , 2011, Panminerva medica.
[48] N. Voelkel,et al. Inhibition of histone deacetylase causes emphysema. , 2011, American journal of physiology. Lung cellular and molecular physiology.
[49] M. Rothenberg,et al. Epigenetic Regulation of the IL-13-induced Human Eotaxin-3 Gene by CREB-binding Protein-mediated Histone 3 Acetylation* , 2011, The Journal of Biological Chemistry.
[50] Xiaoying Wang,et al. Trichostatin Differentially Regulates Th1 and Th2 Responses and Alleviates Rheumatoid Arthritis in Mice , 2011, Journal of Clinical Immunology.
[51] S. Isajevs,et al. Patterns of Inflammatory Responses in Large and Small Airways in Smokers with and without Chronic Obstructive Pulmonary Disease , 2011, Respiration.
[52] H. Timmers,et al. Histone lysine methylation and demethylation pathways in cancer. , 2011, Biochimica et biophysica acta.
[53] D. Strachan,et al. Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. , 2011, The Journal of allergy and clinical immunology.
[54] Hiromasa Inoue,et al. The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in TH2 cells , 2011, Nature Immunology.
[55] C. Rice,et al. Suppression of inflammation by a synthetic histone mimic , 2010, Nature.
[56] Peter A. Jones,et al. Targeting DNA methylation for epigenetic therapy. , 2010, Trends in pharmacological sciences.
[57] H. Magnussen,et al. Reduced miR-146a increases prostaglandin E₂in chronic obstructive pulmonary disease fibroblasts. , 2010, American journal of respiratory and critical care medicine.
[58] M. Kabesch. Next generation genetics in allergy. , 2010, Current opinion in allergy and clinical immunology.
[59] J. Tost,et al. Epigenetic mechanisms and the relationship to childhood asthma , 2010, European Respiratory Journal.
[60] J. Curtis,et al. Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression , 2010, Respiratory research.
[61] William B. Smith,et al. Selective inhibition of BET bromodomains , 2010, Nature.
[62] W. Ellmeier,et al. Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production , 2010, The Journal of Immunology.
[63] Robert A Copeland,et al. Targeting epigenetic enzymes for drug discovery. , 2010, Current opinion in chemical biology.
[64] Aleksandar Milosavljevic,et al. Proinflammatory Role for let-7 MicroRNAS in Experimental Asthma* , 2010, The Journal of Biological Chemistry.
[65] P. Barnes. New therapies for asthma: is there any progress? , 2010, Trends in pharmacological sciences.
[66] S. Davis,et al. Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate , 2010, Oncogene.
[67] Yang Shi,et al. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. , 2010, Annual review of biochemistry.
[68] G. Washko,et al. Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD , 2010, European Respiratory Journal.
[69] Michael A Lopez,et al. Mechanical Stretch Up-regulates MicroRNA-26a and Induces Human Airway Smooth Muscle Hypertrophy by Suppressing Glycogen Synthase Kinase-3β* , 2010, The Journal of Biological Chemistry.
[70] I. Adcock,et al. Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD. , 2010, Chest.
[71] R. Lyle,et al. CD14 polymorphisms and serum CD14 levels through childhood: a role for gene methylation? , 2010, The Journal of allergy and clinical immunology.
[72] Peter J. Barnes,et al. Inhaled Corticosteroids in COPD: A Controversy , 2010, Respiration.
[73] R. Flavell,et al. Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma , 2010, Proceedings of the National Academy of Sciences.
[74] C. Sköld,et al. Remodeling in asthma and COPD – differences and similarities , 2010, The clinical respiratory journal.
[75] D. Schwartz. Epigenetics and environmental lung disease. , 2010, Proceedings of the American Thoracic Society.
[76] Alvis Brazma,et al. A CD8 T cell transcription signature predicts prognosis in autoimmune disease , 2010, Nature Medicine.
[77] B. Garcia,et al. Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D , 2010, Epigenetics & Chromatin.
[78] P. Tak,et al. Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue , 2010, The Journal of Immunology.
[79] Ryan M. O’Connell,et al. Physiological and pathological roles for microRNAs in the immune system , 2010, Nature Reviews Immunology.
[80] Fatima Al-Shahrour,et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. , 2010, Genome research.
[81] I. Adcock,et al. Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils , 2010, Journal of Inflammation.
[82] S. Uhlig,et al. Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. , 2009, Pulmonary pharmacology & therapeutics.
[83] S. Phipps,et al. Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease , 2009, Proceedings of the National Academy of Sciences.
[84] A. Kozyrskyj,et al. Altered epigenetic regulation and increasing severity of bronchial hyperresponsiveness in atopic asthmatic children. , 2009, The Journal of allergy and clinical immunology.
[85] M. Lindsay,et al. Divergent intracellular pathways regulate interleukin‐1β‐induced miR‐146a and miR‐146b expression and chemokine release in human alveolar epithelial cells , 2009, FEBS letters.
[86] I. Adcock,et al. The developmental origins of asthma: does epigenetics hold the key? , 2009, American journal of respiratory and critical care medicine.
[87] Frank D. Gilliland,et al. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. , 2009, American journal of respiratory and critical care medicine.
[88] Yi Zhang,et al. Minireview: role of protein methylation and demethylation in nuclear hormone signaling. , 2009, Molecular endocrinology.
[89] N. Papadopoulos,et al. Association of passive exposure of pregnant women to environmental tobacco smoke with asthma symptoms in children , 2009, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
[90] S. Zukin,et al. Epigenetics , 2009, Alzheimer's & Dementia.
[91] M. Chao,et al. Modification of urinary N7-methylguanine excretion in smokers by glutathione-S-transferase M1 polymorphism. , 2009, Toxicology.
[92] J. M. Phillips,et al. Inhalation of cigarette smoke induces regions of altered DNA methylation (RAMs) in SENCAR mouse lung. , 2009, Toxicology.
[93] Kian Fan Chung,et al. MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy , 2009, PloS one.
[94] I. Adcock,et al. Glucocorticoid resistance in inflammatory diseases , 2009, The Lancet.
[95] A. Shilatifard,et al. An operational definition of epigenetics. , 2009, Genes & development.
[96] K. Shianna,et al. A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci , 2009, PLoS genetics.
[97] Deliang Tang,et al. Relation of DNA Methylation of 5′-CpG Island of ACSL3 to Transplacental Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Childhood Asthma , 2009, PloS one.
[98] D. Doenecke,et al. Histone H1 and its isoforms: contribution to chromatin structure and function. , 2009, Gene.
[99] Christopher B Wilson,et al. Epigenetic control of T-helper-cell differentiation , 2009, Nature Reviews Immunology.
[100] J. Jiricny,et al. DNA Cytosine Demethylation: Are We Getting Close? , 2008, Cell.
[101] Bernhard Kuster,et al. Oxidative stress modulates theophylline effects on steroid responsiveness. , 2008, Biochemical and biophysical research communications.
[102] T. Aune,et al. T-Bet Dependent Removal of Sin3A-Histone Deacetylase Complexes at the Ifng Locus Drives Th1 Differentiation1 , 2008, The Journal of Immunology.
[103] P. Barnes,et al. The cytokine network in asthma and chronic obstructive pulmonary disease. , 2008, The Journal of clinical investigation.
[104] P. Tak,et al. Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? , 2008, Arthritis research & therapy.
[105] Deepti Malhotra,et al. Decline in Nrf2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, Dj-1 , 2022 .
[106] Z. Yakhini,et al. GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas. , 2008, Cancer research.
[107] I. Adcock,et al. Hydrogen Peroxide Prolongs Nuclear Localization of NF-κB in Activated Cells by Suppressing Negative Regulatory Mechanisms* , 2008, Journal of Biological Chemistry.
[108] T. Bestor,et al. The Colorful History of Active DNA Demethylation , 2008, Cell.
[109] P. Howarth,et al. Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. , 2008, The Journal of allergy and clinical immunology.
[110] R. Blumenthal,et al. Mammalian DNA methyltransferases: a structural perspective. , 2008, Structure.
[111] C. Mendelson,et al. Glucocorticoid/glucocorticoid receptor inhibition of surfactant protein-A (SP-A) gene expression in lung type II cells is mediated by repressive changes in histone modification at the SP-A promoter. , 2008, Molecular endocrinology.
[112] O. Kirak,et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223 , 2008, Nature.
[113] P. J. Barnes,et al. Global strategy for asthma management and prevention: GINA executive summary , 2008, European Respiratory Journal.
[114] D. Conti,et al. Glutathione S-Transferase P1, Maternal Smoking, and Asthma in Children: A Haplotype-Based Analysis , 2007, Environmental health perspectives.
[115] A. Kozyrskyj,et al. Epigenetic regulation of established human type 1 versus type 2 cytokine responses. , 2008, The Journal of allergy and clinical immunology.
[116] Nam-Hee Kwon,et al. DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma. , 2008, Journal of clinical immunology.
[117] Nam-Hee Kwon,et al. DNA Methylation and the Expression of IL-4 and IFN-γ Promoter Genes in Patients with Bronchial Asthma , 2008, Journal of Clinical Immunology.
[118] L. Tsaprouni,et al. Suppression of lipopolysaccharide‐ and tumour necrosis factor‐α‐induced interleukin (IL)‐8 expression by glucocorticoids involves changes in IL‐8 promoter acetylation , 2007, Clinical and experimental immunology.
[119] M. Larché. Regulatory T cells in allergy and asthma. , 2007, Chest.
[120] R. Jirtle,et al. Environmental epigenomics and disease susceptibility , 2007, Nature Reviews Genetics.
[121] P. Bromberg,et al. COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1. , 2007, American journal of respiratory cell and molecular biology.
[122] C. Allis,et al. Epigenetics: A Landscape Takes Shape , 2007, Cell.
[123] A. Woodcock,et al. Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment. , 2006, American journal of respiratory and critical care medicine.
[124] D. Baltimore,et al. NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses , 2006, Proceedings of the National Academy of Sciences.
[125] S. Johnston,et al. Molecular mechanisms of respiratory virus-induced asthma and COPD exacerbations and pneumonia. , 2006, Current medicinal chemistry.
[126] I. Adcock,et al. Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma. , 2006, American journal of respiratory and critical care medicine.
[127] I. Rahman,et al. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. , 2006, American journal of physiology. Lung cellular and molecular physiology.
[128] Jianzhu Chen,et al. Inhibition of IFN‐γ transcription by site‐specific methylation during T helper cell development , 2006 .
[129] Bogdan Tanasa,et al. Regulation of Th2 differentiation and Il4 locus accessibility. , 2006, Annual review of immunology.
[130] Kazuhiro Ito,et al. Kinase inhibitors and airway inflammation. , 2006, European journal of pharmacology.
[131] I. Adcock,et al. Epigenetics and airways disease , 2006, Respiratory research.
[132] A. Bird,et al. Genomic DNA methylation: the mark and its mediators. , 2006, Trends in biochemical sciences.
[133] Jianzhu Chen,et al. Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development. , 2006, The EMBO journal.
[134] P. Barnes. Emerging targets for COPD therapy. , 2005, Current drug targets. Inflammation and allergy.
[135] T. Spector,et al. Epigenetic differences arise during the lifetime of monozygotic twins. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[136] I. Adcock,et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. , 2005, The New England journal of medicine.
[137] F. Gilliland,et al. Maternal and grandmaternal smoking patterns are associated with early childhood asthma. , 2005, Chest.
[138] T. Collins,et al. Chromatin Modification and the Endothelial-specific Activation of the E-selectin Gene* , 2005, Journal of Biological Chemistry.
[139] C. Burge,et al. Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.
[140] Irina Petrache,et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. , 2004, The Journal of clinical investigation.
[141] I. Rahman,et al. Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression. , 2004, Biochemical pharmacology.
[142] Irfan Rahman,et al. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. , 2004, American journal of respiratory cell and molecular biology.
[143] S. Lerner,et al. Effects of the histone deacetylase inhibitor FK228 in improving adenoviral mediated gene expression and suicide gene therapy inhumanTCC-sup bladder cancer , 2004 .
[144] I. Adcock,et al. Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase , 2004, The Lancet.
[145] I. Adcock,et al. Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. , 2004, Biochemical and biophysical research communications.
[146] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[147] F. Antequera,et al. Structure, function and evolution of CpG island promoters , 2003, Cellular and Molecular Life Sciences CMLS.
[148] A. Rao,et al. An epigenetic view of helper T cell differentiation , 2003, Nature Immunology.
[149] G. Abecasis,et al. Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma , 2003, Nature Genetics.
[150] C. Braun-Fahrländer,et al. Do only European cattle protect from allergies? , 2002, Allergy.
[151] I. Adcock,et al. Expression and activity of histone deacetylases in human asthmatic airways. , 2002, American journal of respiratory and critical care medicine.
[152] Anjana Rao,et al. TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes , 2002, Nature Immunology.
[153] Suneet Agarwal,et al. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. , 2002, Immunity.
[154] A. Bird. DNA methylation patterns and epigenetic memory. , 2002, Genes & development.
[155] I. Adcock,et al. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages , 2001 .
[156] I. Adcock,et al. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.