论文信息 - Myxomatous transformation of heart valves in Florida manatees (Trichechus manatus latirostris)

Myxomatous transformation of heart valves in Florida manatees (Trichechus manatus latirostris)

The finding of thickened atrioventricular valves in the heart of a neonate Florida manatee (Trichechus manatus latirostris) prompted a retrospective study of 26 previously collected manatee hearts. Eight of 26 hearts had valvular thickenings on gross examination. Microscopically, the thickenings were the result of excessive numbers of fibroblasts embedded in a mucopolysac charide-rich matrix within the spongiosa layer of the valvular leaflets. Ultrastructurally, the thickened valve leaflets of one manatee heart showed active mesenchymal cells surrounded by ground substance and collagen fibrils. The morphologic findings closely resembled a similar condition of valves found in older dogs and humans. Unlike the condition in dogs and humans, the valvular condition in manatees is considered incidental.

T. O'Shea | C. Buergelt | C. Beck | R. Bonde

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