Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
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A. Palmeri | L. Honig | E. Sigurdsson | P. Fraser | O. Arancio | M. Sierks | K. Duff | I. Chatterjee | D. Puzzo | W. Gulisano | C. Grassi | W. H. Yu | N. Kanaan | L. D’Adamio | W. H. Yu | Hong Zhang | Agnieszka Staniszewski | H. Berman | Jing Li | R. Piacentini | C. Ripoli | V. Haroutunian | D. D. Li Puma | Claudio Grassi | P. Lopez | A. Teich | D. L. Puma | H. Zhang | M. A. Baltrons | Jing Li | F. Saeed | E. Davidowitz | J. Gonzalez | L. Brown | J. Moe | Mauro Fa’ | A. Staniszewski | Huilai Tian | M. Fa | J. Li | H. Tian | J. Costa | Faisal Saeed | Hanna Berman | Juana Gonzalez | Peter A. Lopez | Walter Gulisano | Eliot J Davidowitz | C. Grassi
[1] H. Vinters,et al. Pre‐synaptic C‐terminal truncated tau is released from cortical synapses in Alzheimer's disease , 2015, Journal of neurochemistry.
[2] M. Diamond,et al. Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation* , 2015, The Journal of Biological Chemistry.
[3] M. Frotscher,et al. Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation , 2015, Acta neuropathologica communications.
[4] D. Puzzo,et al. Intracellular Accumulation of Amyloid-β (Aβ) Protein Plays a Major Role in Aβ-Induced Alterations of Glutamatergic Synaptic Transmission and Plasticity , 2014, The Journal of Neuroscience.
[5] M. Diamond,et al. Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target* , 2014, The Journal of Biological Chemistry.
[6] E. Mandelkow,et al. Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity* , 2014, The Journal of Biological Chemistry.
[7] D. Holtzman,et al. Neuronal activity regulates extracellular tau in vivo , 2014, The Journal of experimental medicine.
[8] M. Tolnay,et al. Intercellular transfer of tau aggregates and spreading of tau pathology: Implications for therapeutic strategies , 2014, Neuropharmacology.
[9] Clemens F. Kaminski,et al. Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology* , 2013, The Journal of Biological Chemistry.
[10] M. Sierks,et al. Trimeric Tau Is Toxic to Human Neuronal Cells at Low Nanomolar Concentrations , 2013, International journal of cell biology.
[11] E. Mufson,et al. Prefibrillar Tau Oligomers in Mild Cognitive Impairment and Alzheimer's Disease , 2013, Neurodegenerative Diseases.
[12] G. Hall,et al. Tangles, Toxicity, and Tau Secretion in AD – New Approaches to a Vexing Problem , 2013, Front. Neurol..
[13] Wendy Noble,et al. Physiological release of endogenous tau is stimulated by neuronal activity , 2013, EMBO reports.
[14] O. Arancio,et al. Synthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease. , 2013, European journal of medicinal chemistry.
[15] C. Zurzolo,et al. Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons* , 2012, The Journal of Biological Chemistry.
[16] U. Sengupta,et al. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau , 2012, Scientific Reports.
[17] B. Hyman,et al. Soluble forms of tau are toxic in Alzheimer’s disease , 2012, Translational neuroscience.
[18] J. Lancia,et al. Tau oligomers and tau toxicity in neurodegenerative disease. , 2012, Biochemical Society transactions.
[19] U. Sengupta,et al. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[20] A. Andreadis,et al. Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport , 2012, Neurobiology of Aging.
[21] D. Holtzman,et al. Tau elevations in the brain extracellular space correlate with reduced amyloid-β levels and predict adverse clinical outcomes after severe traumatic brain injury. , 2012, Brain : a journal of neurology.
[22] D. Holtzman,et al. Trans-cellular Propagation of Tau Aggregation by Fibrillar Species* , 2012, The Journal of Biological Chemistry.
[23] Naruhiko Sahara,et al. Propagation of Tau Pathology in a Model of Early Alzheimer's Disease , 2012, Neuron.
[24] Menno P. Witter,et al. Trans-Synaptic Spread of Tau Pathology In Vivo , 2012, PloS one.
[25] A. Palamara,et al. HSV-1 promotes Ca2+-mediated APP phosphorylation and Aβ accumulation in rat cortical neurons , 2011, Neurobiology of Aging.
[26] A. Andreadis,et al. Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases , 2011, The Journal of Neuroscience.
[27] Giovanni B. Frisoni,et al. The Alzheimer’s Association external quality control program for cerebrospinal fluid biomarkers , 2011, Alzheimer's & Dementia.
[28] N. Nukina,et al. Tau Protein Assembles into Isoform- and Disulfide-dependent Polymorphic Fibrils with Distinct Structural Properties* , 2011, The Journal of Biological Chemistry.
[29] Meaghan Morris,et al. The Many Faces of Tau , 2011, Neuron.
[30] M. Glucksman,et al. Characterization of Prefibrillar Tau Oligomers in Vitro and in Alzheimer Disease* , 2011, The Journal of Biological Chemistry.
[31] I. Heuser,et al. Comparison of Immunosorbent Assays for the Quantification of Biomarkers for Alzheimer’s Disease in Human Cerebrospinal Fluid , 2011, Dementia and Geriatric Cognitive Disorders.
[32] R. Kayed,et al. Preparation and characterization of neurotoxic tau oligomers. , 2010, Biochemistry.
[33] Sangmook Lee,et al. Secretion of human tau fragments resembling CSF‐tau in Alzheimer's disease is modulated by the presence of the exon 2 insert , 2010, FEBS letters.
[34] O. Arancio,et al. Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices. , 2010, Journal of visualized experiments : JoVE.
[35] J. Trojanowski,et al. Characterization of tau fibrillization in vitro , 2010, Alzheimer's & Dementia.
[36] P. Davies,et al. Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology , 2009, The Journal of Neuroscience.
[37] Martin Beibel,et al. Transmission and spreading of tauopathy in transgenic mouse brain , 2009, Nature Cell Biology.
[38] M. Diamond,et al. Propagation of Tau Misfolding from the Outside to the Inside of a Cell* , 2009, Journal of Biological Chemistry.
[39] Bradley T. Hyman,et al. Tau pathophysiology in neurodegeneration: a tangled issue , 2009, Trends in Neurosciences.
[40] A. Kozikowski,et al. The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity , 2009, Journal of neuroscience research.
[41] M. Sierks,et al. Characterizing antibody specificity to different protein morphologies by AFM. , 2009, Langmuir : the ACS journal of surfaces and colloids.
[42] A. Palmeri,et al. Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus , 2008, The Journal of Neuroscience.
[43] M. Novák,et al. High-yield purification of fetal tau preserving its structure and phosphorylation pattern. , 2008, Journal of immunological methods.
[44] Z. Khachaturian. Alzheimer's & Dementia: The Journal of the Alzheimer's Association , 2008, Alzheimer's & Dementia.
[45] S. Maeda,et al. Assembly of two distinct dimers and higher‐order oligomers from full‐length tau , 2007, The European journal of neuroscience.
[46] K. Ashe,et al. Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of Tauopathy , 2007, The Journal of Neuroscience.
[47] D. Diamond,et al. Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice , 2006, Nature Protocols.
[48] Steven Mennerick,et al. Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo , 2005, Neuron.
[49] H. Liebig,et al. Rapid purification of truncated tau proteins: model approach to purification of functionally active fragments of disordered proteins, implication for neurodegenerative diseases. , 2004, Protein expression and purification.
[50] Ottavio Arancio,et al. Presynaptic CaMKII Is Necessary for Synaptic Plasticity in Cultured Hippocampal Neurons , 2004, Neuron.
[51] J. Ávila,et al. Quinones facilitate the self-assembly of the phosphorylated tubulin binding region of tau into fibrillar polymers. , 2004, Biochemistry.
[52] C. Barbato,et al. Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons , 2004, Cell Death and Differentiation.
[53] C. Finch,et al. Self-assembly of Aβ1-42 into globular neurotoxins , 2003 .
[54] P. Davies,et al. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms , 2003, Journal of neurochemistry.
[55] R. Malinow,et al. APP Processing and Synaptic Function , 2003, Neuron.
[56] E. Kandel,et al. Rapid Increase in Clusters of Presynaptic Proteins at Onset of Long-Lasting Potentiation , 2001, Science.
[57] D. Wilson,et al. Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease. , 1997, The American journal of pathology.
[58] E. Mandelkow,et al. RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments , 1996, FEBS letters.
[59] R. Crowther,et al. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans , 1996, Nature.
[60] J. Ávila,et al. Polymerization of τ into Filaments in the Presence of Heparin: The Minimal Sequence Required for τ ‐ τ Interaction , 1996 .
[61] Joseph E LeDoux,et al. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. , 1992, Behavioral neuroscience.
[62] Deborah Moran,et al. Data-independent acquisition (MSE) with ion mobility provides a systematic method for analysis of a bacteriophage structural proteome. , 2014, Journal of virological methods.
[63] U. Sengupta,et al. Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds. , 2014, Journal of Alzheimer's disease : JAD.
[64] J. Lancia,et al. TOC1: characterization of a selective oligomeric tau antibody. , 2013, Journal of Alzheimer's disease : JAD.
[65] Sangmook Lee,et al. Interneuronal transfer of human tau between Lamprey central neurons in situ. , 2010, Journal of Alzheimer's disease : JAD.
[66] John Q Trojanowski,et al. Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments. , 2008, Journal of Alzheimer's disease : JAD.
[67] David M Holtzman,et al. Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. , 2005, Neuron.
[68] H. Braak,et al. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads , 2004, Acta Neuropathologica.
[69] C. Finch,et al. Self-assembly of Abeta(1-42) into globular neurotoxins. , 2003, Biochemistry.
[70] J. Ávila,et al. Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction. , 1996, Journal of neurochemistry.