Interaction of Molecularly Imprinted Polymers with Creatinine

Memory sites toward clinically relevant creatinine have been imparted in polymers based on methacrylic acid, N-vinyl pyrrolidine, and 2-hydroxy ethyl methacrylate by the technique of molecular imprinting. The polymers are subjected to interaction with creatinine and creatine, a molecule of close resemblance with creatinine. The results show that selectivity is largely governed by the nature of the monomer. The reusability of the polymer is also demonstrated. © 1997 John Wiley & Sons, Inc. J Appl Polym Sci 66: 2539–2542, 1997