A New Active Contours Approach for Finger Extensor Tendon Segmentation in Ultrasound Images Using Prior Knowledge and Phase Symmetry

This work proposes a new approach for the segmentation of the extensor tendon in ultrasound images of the second metacarpophalangeal joint (MCPJ). The MCPJ is known to be frequently involved in early stages of rheumatic diseases like rheumatoid arthritis. The early detection and follow up of these diseases is important to start and adapt the treatments properly and, in that way, preventing irreversible damage of the joints. This work relies on an active contours framework, preceded by a phase symmetry preprocessing and with prior knowledge energies, to automatically identify the extensor tendon. Active contours methods are widely used in ultrasound images because of their robustness to speckle noise and ability to join unconnected smaller regions into a coherent shape. The tendon is formulated as a line so open ended active contours were used. Phase symmetry highlights the tendon, by setting a proper scale range and angle span. The distance between structures and the tendon slope were also included to enforce the model based on anatomical characteristics. And finally, the concavity measures were used because, given the anatomy of the finger, we know that the tendon line should have less than two concavities. To solve the active contours energy minimization a genetic algorithm approach was used. Several energy metric configurations were compared using the modified Hausdorff distance and results showed that this segmentation is not only possible, but exhibits errors smaller than 0.5 mm with a confidence of 95% with the phase symmetry preprocessing and energies based on the line neighborhood, area ratio, slope, and concavity measurements.

[1]  S. Geraci,et al.  Rheumatoid arthritis: diagnosis and management. , 2007, The American journal of medicine.

[2]  Yasser El Miedany Musculoskeletal ultrasonography in rheumatic diseases , 2015 .

[3]  Nassir Navab,et al.  Ultrasonic image analysis and image-guided interventions , 2011, Interface Focus.

[4]  Enrico Grisan,et al.  Improved detection of synovial boundaries in ultrasound examination by using a cascade of active-contours. , 2013, Medical engineering & physics.

[5]  Tamotsu Kamishima,et al.  Ultrasound Assessment of Synovial Pathologic Features in Rheumatoid Arthritis Using Comprehensive Multiplane Images of the Second Metacarpophalangeal Joint: Identification of the Components That Are Reliable and Influential on the Global Assessment of the Whole Joint , 2014, Arthritis & rheumatology.

[6]  R. Yood,et al.  Guidelines for the management of rheumatoid arthritis: 2002 Update. , 2002, Arthritis and rheumatism.

[7]  B. Dasgupta,et al.  Role of diagnostic ultrasound in the assessment of musculoskeletal diseases , 2012, Therapeutic advances in musculoskeletal disease.

[8]  Hiroki Shirato,et al.  Power Doppler ultrasound of rheumatoid synovitis: quantification of vascular signal and analysis of interobserver variability , 2009, Skeletal Radiology.

[9]  W. Grassi,et al.  Ultrasonography in rheumatology: an evolving technique , 1998, Annals of the rheumatic diseases.

[10]  David E. Goldberg,et al.  Genetic Algorithms in Search Optimization and Machine Learning , 1988 .

[11]  C. Schueller-weidekamm Quantification of synovial and erosive changes in rheumatoid arthritis with ultrasound--revisited. , 2009, European journal of radiology.

[12]  Atlanta,et al.  Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I. , 2008, Arthritis and rheumatism.

[13]  Nikolas Petteri Tiilikainen,et al.  A Comparative Study of Active Contour Snakes , 2007 .

[14]  Peter Kovesi,et al.  Symmetry and Asymmetry from Local Phase , 1997 .

[15]  Karolina Nurzynska,et al.  Segmentation of finger joint synovitis in ultrasound images , 2016, 2016 IEEE Sixth International Conference on Communications and Electronics (ICCE).

[16]  Edgar Brunner,et al.  A novel ultrasonographic synovitis scoring system suitable for analyzing finger joint inflammation in rheumatoid arthritis. , 2005, Arthritis and rheumatism.

[17]  Anil K. Jain,et al.  A modified Hausdorff distance for object matching , 1994, Proceedings of 12th International Conference on Pattern Recognition.

[18]  Miguel Tavares Coimbra,et al.  Automatic Segmentation of Extensor Tendon of the MCP Joint in Ultrasound Images , 2016, BIOIMAGING.

[19]  Miguel Tavares Coimbra,et al.  Segmentation of bones & MCP joint region of the hand from ultrasound images , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[20]  Karolina Nurzynska,et al.  Automatic finger joint synovitis localization in ultrasound images , 2016, Photonics Europe.

[21]  G. Fichtinger,et al.  P6D-2 Ultrasound Bone Segmentation Using Dynamic Programming , 2007, 2007 IEEE Ultrasonics Symposium Proceedings.

[22]  Ultrasonography in rheumatology: developing its potential in clinical practice and research. , 2007, Rheumatology.

[23]  S. Gabriel,et al.  Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. , 2008, Arthritis and rheumatism.

[24]  Bogdan Smolka,et al.  Automatic detection of bones based on the confidence map for Rheumatoid Arthritis analysis , 2015 .

[25]  Antony J Hodgson,et al.  Bone surface localization in ultrasound using image phase-based features. , 2009, Ultrasound in medicine & biology.