This study gathers novel evidence on the interplay between the organisational and the individual mechanisms that affect the continued use of Electronic Medical Record (EMR) in hospitals. Our model integrates mechanisms inspired by both Institutional Theory (i.e., organisational expectations, change culture and alignment of meaning systems) and Technology Acceptance Models (i.e., perceived usefulness and ease of use). Tested on hospital professionals, our results point out the predominant role played by rational, individual-level mechanisms and the interplay with organisational expectations, as the only institutional factor that affects the continued use through both direct and mediate relationships.