Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2.

[1]  Matthieu Hamel,et al.  Journal of Medicinal Chemistry , 2010 .

[2]  P. Kalinski.  Regulation of Immune Responses by Prostaglandin E2 , 2012, The Journal of Immunology.

[3]  K. Rangappa,et al.  A Simple and Efficient Method for the Synthesis of 1,2‐Benzisoxazoles: A Series of Its Potent Acetylcholinesterase Inhibitors. , 2004 .

[4]  C. Kavitha,et al.  Synthesis and pharmacological evaluation of novel N-alkyl/aryl substituted thiazolidinone arecoline analogues as muscarinic receptor 1 agonist in Alzheimer's dementia models. , 2009, European journal of medicinal chemistry.

[5]  T. R. Swaroop,et al.  Synthesis and Cholinesterase Inhibition Activity of New Pyrrolopyrimidine Derivatives , 2014 .

[6]  A. J. van der Lely,et al.  Chronic inflammation in psoriasis and obesity: implications for therapy. , 2006, Medical hypotheses.

[7]  Garret A. FitzGerald,et al.  Prostaglandins and Inflammation , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[8]  Basappa,et al.  Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells. , 2015, Bioorganic & medicinal chemistry letters.

[9]  A. Venkataraman,et al.  Chemoselective transfer hydrogenation reactions over nanosized γ-Fe2O3 catalyst prepared by novel combustion route , 2007 .

[10]  C. Noguera.  Physics and Chemistry at Oxide Surfaces , 2005 .

[11]  Chong Hak Chae,et al.  Computational studies of COX-2 inhibitors: 3D-QSAR and docking. , 2004, Bioorganic & medicinal chemistry.

[12]  P. Lipsky,et al.  Cyclooxygenase in biology and disease , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[13]  B. Tidor,et al.  Rational Approaches to Improving Selectivity in Drug Design , 2012, Journal of medicinal chemistry.

[14]  A. Sobel,et al.  The Journal of Biological Chemistry. , 2009, Nutrition reviews.

[15]  Garret A. FitzGerald,et al.  COX-2 and beyond: approaches to prostaglandin inhibition in human disease , 2003, Nature Reviews Drug Discovery.

[16]  P. Libby,et al.  Inflammation and Atherosclerosis , 2002, Circulation.

[17]  R. Flower.  The development of COX2 inhibitors , 2003, Nature Reviews Drug Discovery.

[18]  Basappa,et al.  Novel delta2-isoxazolines as group II phospholipase A2 inhibitors. , 2004, Bioorganic & medicinal chemistry letters.

[19]  L. Coussens,et al.  Inflammation and cancer , 2002, Nature.

[20]  Basappa,et al.  Solution-phase synthesis of novel delta2-isoxazoline libraries via 1,3-dipolar cycloaddition and their antifungal properties. , 2003, Bioorganic & medicinal chemistry.

[21]  A. Dobrian,et al.  Functional and pathological roles of the 12- and 15-lipoxygenases. , 2011, Progress in lipid research.

[22]  Basappa,et al.  Synthesis and characterization of novel 1,2-oxazine-based small molecules that targets acetylcholinesterase. , 2014, Bioorganic & medicinal chemistry letters.

[23]  T. Schnitzer,et al.  Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials , 2013, BDJ.

[24]  F. Venuta,et al.  Journal of Thoracic and Cardiovascular Surgery , 2011 .

[25]  Basappa,et al.  Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma. , 2015, Bioorganic & medicinal chemistry letters.

[26]  John A. Smith.  Neutrophils, host defense, and inflammation: a double‐edged sword , 1994, Journal of leukocyte biology.

[27]  Basappa,et al.  Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma in Vitro and in Vivo* , 2014, The Journal of Biological Chemistry.

[28]  F. Khodagholi,et al.  Attenuation of LPS-induced apoptosis in NGF-differentiated PC12 cells via NF-κB pathway and regulation of cellular redox status by an oxazine derivative. , 2011, Biochimie.

[29]  L. Curtiss,et al.  Arteriosclerosis, Thrombosis, and Vascular Biology. , 2016, Arteriosclerosis, thrombosis, and vascular biology.

[30]  Basappa,et al.  Synthesis and Characterization of Novel 2-Amino-Chromene-Nitriles that Target Bcl-2 in Acute Myeloid Leukemia Cell Lines , 2014, PloS one.

[31]  V. A. Tartakovsky,et al.  A General Metal‐Assisted Synthesis of α‐Halo Oxime Ethers from Nitronates and Nitro Compounds , 2014 .

[32]  Basappa,et al.  Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo* , 2014, The Journal of Biological Chemistry.

[33]  Basappa,et al.  Preparation and use of combustion-derived Bi2O3 for the synthesis of heterocycles with anti-cancer properties by Suzuki-coupling reactions , 2014 .