论文信息 - BET 1: Prednisolone for the treatment of acute gouty arthritis

BET 1: Prednisolone for the treatment of acute gouty arthritis

A short cut review was carried out to establish whether corticosteroids are safe and effective in managing the symptoms of acute gouty arthritis. Five studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that corticosteroids are an effective and safe alternative to non steroidal anti inflammatory drugs (NSAIDs) in patients presenting with acute gouty arthritis.

Richard C. Taylor

[1] Meiping Guan,et al. Comparison of Prednisolone, Etoricoxib, and Indomethacin in Treatment of Acute Gouty Arthritis: An Open-Label, Randomized, Controlled Trial , 2016, Medical science monitor : international medical journal of experimental and clinical research.

[2] T. Rainer,et al. Oral Prednisolone in the Treatment of Acute Gout: A Pragmatic, Multicenter, Double-Blind, Randomized Trial. , 2016, Annals of internal medicine.

[3] C. Weel,et al. Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial , 2008, The Lancet.

[4] P. Lucassen,et al. Systemic corticosteroids for acute gout. , 2008, The Cochrane database of systematic reviews.

[5] P. Cameron,et al. Comparison of Oral Prednisolone/Paracetamol and Oral Indomethacin/Paracetamol Combination Therapy in the Treatment of Acute Goutlike Arthritis: A Double-Blind, Randomized, Controlled Trial , 2007, Annals of Emergency Medicine.