A power and data front-end IC for biomedical monitoring systems

To enable the evolution towards electronically assisted healthcare, future medical implants require sensors and processing circuitry to inform patient and doctor on the rehabilitation status. An important branch of systems are those where implant strain is monitored through strain gauges. Since batteries inside the human body are avoided as much as possible, a transcutaneous power link is used to wirelessly power the implant. The same RF link provides an elegant way of establishing bi-directional data communication between the external base station and the medical device. This paper describes a front-end IC that manages both power reception and bi-directional data communication. It has a clock generation circuit on board to drive additional digital processing circuits. A new architecture that uses a current driven data demodulation principle is introduced. It is able to detect an AM signal with modulation depth of a mere 4%, which is better than recent similar systems in the field. The IC is fabricated in a solid 0.35 μm HVCMOS technology and consumes only 0.56 mA.

[1]  Ying Yao,et al.  An Implantable Microsystem for Wireless Multi-Channel Cortical Recording , 2007, TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference.

[2]  José Silva-Martínez,et al.  A frequency compensation scheme for LDO voltage regulators , 2004, IEEE Transactions on Circuits and Systems I: Regular Papers.

[3]  Fredy Segura-Quijano,et al.  Bidirectional telemetry for implantable systems , 2006, 2006 IEEE International Symposium on Circuits and Systems.

[4]  L. A. Glasser,et al.  A magnetic power and communication interface for a CMOS integrated circuit , 1989 .

[5]  Reid R. Harrison,et al.  Micropower circuits for bidirectional wireless telemetry in neural recording applications , 2005, IEEE Transactions on Biomedical Engineering.

[6]  Maysam Ghovanloo,et al.  Fully-Integrated CMOS Power Regulator for Telemetry-Powered Implantable Biomedical Microsystems , 2006, IEEE Custom Integrated Circuits Conference 2006.

[7]  Robert Puers,et al.  An inductive power system with integrated bi-directional data-transmission , 2004 .

[8]  I. Iakovidis,et al.  Biomedical Engineering and eHealth min Europe - Outcomes and Challenges of Past and Current EU Research Programs , 2007, IEEE Engineering in Medicine and Biology Magazine.

[9]  O Paiva,et al.  Concept, design and fabrication of smart orthopedic implants. , 2000, Medical engineering & physics.

[10]  Robert Puers,et al.  An inductive power link for a wireless endoscope. , 2007, Biosensors & bioelectronics.

[11]  W. Sansen,et al.  A 1 GHz continuous-time sigma-delta A/D converter in 90 nm standard CMOS , 2005, IEEE MTT-S International Microwave Symposium Digest, 2005..

[12]  M. Ghovanloo,et al.  Fully integrated wideband high-current rectifiers for inductively powered devices , 2004, IEEE Journal of Solid-State Circuits.

[13]  B.J. Hosticka,et al.  A programmable intraocular CMOS pressure sensor system implant , 2001, Proceedings of the 26th European Solid-State Circuits Conference.

[14]  Robert G. Meyer,et al.  Analysis and Design of Analog Integrated Circuits , 1993 .

[15]  P. Loizou Introduction to cochlear implants. , 1999, IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society.

[16]  A. Brokaw,et al.  A simple three-terminal IC bandgap reference , 1974 .

[17]  P. A. Neukomm,et al.  Passive wireless actuator control and sensor signal transmission , 1990 .

[18]  Robert Puers,et al.  Design and Packaging of a Fully Autonomous Medical Monitoring System for Dental Applications , 2007, IEEE Transactions on Circuits and Systems I: Regular Papers.

[19]  W. Liu,et al.  A neuro-stimulus chip with telemetry unit for retinal prosthetic device , 2000, IEEE Journal of Solid-State Circuits.