Intrathecal coadministration of clonidine with serotonin receptor agonists produces supra-additive visceral antinociception in the rat

[1]  T. Archer,et al.  Complete blockade and attenuation of 5-hydroxytryptamine induced analgesia following NA depletion in rats and mice. , 2009, Acta pharmacologica et toxicologica.

[2]  G. Gebhart,et al.  Evidence that spinal 5-HT1, 5-HT2 and 5-HT3 receptor subtypes modulate responses to noxious colorectal distension in the rat , 1991, Brain Research.

[3]  G. Gebhart,et al.  Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception. , 1990, The Journal of pharmacology and experimental therapeutics.

[4]  M. Spedding,et al.  Heterogeneity of α2‐adrenoceptors in rat cortex but not human platelets can be defined by 8‐OH‐DPAT, RU 24969 and methysergide , 1990, British journal of pharmacology.

[5]  M. Brody,et al.  Pharmacological characterization of alpha adrenoceptors involved in the antinociceptive and cardiovascular effects of intrathecally administered clonidine. , 1989, The Journal of pharmacology and experimental therapeutics.

[6]  S. Peroutka 5-Hydroxytryptamine receptor subtypes: molecular, biochemical and physiological characterization , 1988, Trends in Neurosciences.

[7]  R. Graham,et al.  Identification of structurally distinct alpha 2-adrenergic receptors. , 1988, The Journal of biological chemistry.

[8]  G. Gebhart,et al.  Inhibition of spinal nociceptive transmission from the midbrain, pons and medulla in the rat: activation of descending inhibition by morphine, glutamate and electrical stimulation , 1988, Brain Research.

[9]  K. Omote,et al.  Serotonergic mediation of spinal analgesia and its interaction with noradrenergic systems. , 1988, Anesthesiology.

[10]  M. Caron,et al.  Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[11]  T. Ness,et al.  Colorectal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat , 1988, Brain Research.

[12]  T. Ness,et al.  A distension control device useful for quantitative studies of hollow organ sensation , 1987, Physiology and Behavior.

[13]  M. Caron,et al.  Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. , 1987, Science.

[14]  G. Gebhart,et al.  Quantitative characterization of ceruleospinal inhibition of nociceptive transmission in the rat. , 1986, Journal of neurophysiology.

[15]  S. Hunskaar,et al.  Lesions of the ascending serotonergic pathways and antinociceptive effects after systemic administration of p-chloroamphetamine in mice , 1986, Pharmacology Biochemistry and Behavior.

[16]  T. Archer,et al.  Noradrenergic-serotonergic interactions and nociception in the rat. , 1986, European journal of pharmacology.

[17]  T. Archer,et al.  Blockade of intrathecal 5-hydroxytryptamine-induced antinociception in rats by noradrenaline depletion , 1985, Neuroscience Letters.

[18]  H. Fields,et al.  Lumbar intrathecal naloxone blocks analgesia produced by microstimulation of the ventromedial medulla in the rat , 1982, Brain Research.

[19]  H. Proudfit Reversible inactivation of raphe magnus neurons: effects on nociceptive threshold and morphine-induced analgesia , 1980, Brain Research.

[20]  T. Yaksh,et al.  Spinal cord pharmacology of adrenergic agonist-mediated antinociception. , 1980, The Journal of pharmacology and experimental therapeutics.

[21]  D. Pfaff,et al.  Noradrenergic and serotonergic mediation of spinal analgesia mechanisms. , 1980, European journal of pharmacology.

[22]  T. Yaksh,et al.  Spinal serotonin terminal system mediates antinociception. , 1979, The Journal of pharmacology and experimental therapeutics.

[23]  R. Ryall,et al.  The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurones in the cat , 1978, Brain Research.

[24]  H. Fields,et al.  Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons , 1977, Brain Research.

[25]  T. Yaksh,et al.  Chronic catheterization of the spinal subarachnoid space , 1976, Physiology & Behavior.

[26]  K. Hole,et al.  Response to electric shock in rats: Effects of selective midbrain raphe lesions , 1975, Pharmacology Biochemistry and Behavior.

[27]  A Cowan,et al.  Statistical analysis of drug-drug and site-site interactions with isobolograms. , 1989, Life sciences.

[28]  A. Gilman,et al.  G proteins: transducers of receptor-generated signals. , 1987, Annual review of biochemistry.

[29]  K. Starke Regulation of noradrenaline release by presynaptic receptor systems. , 1977, Reviews of physiology, biochemistry and pharmacology.