The role of carcinogen-metabolizing enzyme polymorphisms in cancer susceptibility.
暂无分享,去创建一个
[1] J. Brockmöller,et al. Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. , 1996, Cancer research.
[2] F. Guengerich,et al. Characterization of purified human recombinant cytochrome P4501A1-Ile462 and -Val462: assessment of a role for the rare allele in carcinogenesis. , 1996, Cancer research.
[3] T. Rustan,et al. Human N-acetylation of benzidine: role of NAT1 and NAT2. , 1996, Cancer research.
[4] M. Yamamoto,et al. Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. , 1996, Cancer research.
[5] M. Ingelman-Sundberg,et al. Nomenclature for human CYP2D6 alleles. , 1996, Pharmacogenetics.
[6] P. Beaune,et al. Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype. , 1996, Pharmacogenetics.
[7] E. Perez-stable,et al. CYP2D6 phenotype and the metabolism of nicotine and cotinine. , 1996, Pharmacogenetics.
[8] R. Hayes,et al. The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[9] D W Nebert,et al. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. , 1996, Pharmacogenetics.
[10] Harris Cc,et al. The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene. , 1996, British Journal of Cancer.
[11] O. Gotoh,et al. cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization. , 1996, Biochemical and biophysical research communications.
[12] P. Dayer,et al. The effect of tobacco on lung cancer risk depends on CYP2D6 activity. , 1996, Cancer research.
[13] S. London,et al. Lung cancer risk in African-Americans in relation to a race-specific CYP1A1 polymorphism. , 1995, Cancer research.
[14] Y. Fujii‐Kuriyama,et al. Polymorphic forms of the Ah receptor and induction of the CYP1A1 gene. , 1995, Pharmacogenetics.
[15] J. Barrett. Mechanisms for species differences in receptor-mediated carcinogenesis. , 1995, Mutation research.
[16] N. Rothman,et al. Lung cancer and CYP2D6 (the debrisoquine polymorphism): sources of heterogeneity in the proposed association. , 1995, Pharmacogenetics.
[17] P. de Coppet,et al. Human glutathione S-transferase M1 null genotype is associated with a high inducibility of cytochrome P450 1A1 gene transcription. , 1995, Cancer research.
[18] P. Fernández-Salguero,et al. The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis. , 1995, Pharmacogenetics.
[19] D. Bell,et al. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. , 1995, Cancer research.
[20] D. Bell,et al. Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue. , 1995, Cancer research.
[21] P. Beaune,et al. CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure. , 1995, Carcinogenesis.
[22] V. Dolžan,et al. Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls. , 1995, Carcinogenesis.
[23] K. Noda,et al. Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population. , 1995, Carcinogenesis.
[24] E. Gallagher,et al. Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity. , 1995, Pharmacogenetics.
[25] O Pelkonen,et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. , 1995, American journal of human genetics.
[26] K. Nakachi,et al. Association of cigarette smoking and CYP1A1 polymorphisms with adenocarcinoma of the lung by grades of differentiation. , 1995, Carcinogenesis.
[27] S. London,et al. Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California. , 1995, Journal of the National Cancer Institute.
[28] D. Bell,et al. Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer. , 1995, Cancer research.
[29] M. Denison,et al. Xenobiotic-inducible Transcription of Cytochrome P450 Genes (*) , 1995, The Journal of Biological Chemistry.
[30] T. Nurminen,et al. Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: association with GSTM1 polymorphism, smoking, and asbestos exposure. , 1995, Cancer research.
[31] K. Buetow,et al. Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking. , 1995, Pharmacogenetics.
[32] G. Chenevix-Trench,et al. Glutathione S-transferase M1 and T1 polymorphisms: susceptibility to colon cancer and age of onset. , 1995, Carcinogenesis.
[33] P. Engstrom,et al. Glutathione S-Transferase Activity and Glutathione S-Transferase μ Expression in Subjects with Risk for Colorectal Cancer , 1995 .
[34] E. Bowman,et al. Human Lung Carcinogen—DNA Adduct Levels Mediated by Genetic Polymorphisms In Vivo , 1995 .
[35] G. Semenza,et al. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[36] R. Kim,et al. Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms , 1995, Clinical pharmacology and therapeutics.
[37] Hayes-Davis Rb. Genetic susceptibility and occupational cancer. , 1995 .
[38] I. Phillips,et al. The molecular biology of the flavin-containing monooxygenases of man. , 1995, Chemico-biological interactions.
[39] K. McGlynn,et al. Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[40] E. Bresnick,et al. Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities. , 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[41] M. Costa. Model for the epigenetic mechanism of action of nongenotoxic carcinogens. , 1995, American Journal of Clinical Nutrition.
[42] T. Katoh,et al. Cytochrome P4501A1 gene polymorphism and homozygous deletion of the glutathione S-transferase M1 gene in urothelial cancer patients. , 1995, Carcinogenesis.
[43] M. Relling,et al. Nomenclature for N-acetyltransferases. , 1995, Pharmacogenetics.
[44] E. Vesell,et al. Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe. , 1995, Pharmacogenetics.
[45] E. Taioli,et al. Functional significance of different human CYP1A1 genotypes. , 1994, Carcinogenesis.
[46] J. Goldstein,et al. Biochemistry and molecular biology of the human CYP2C subfamily. , 1994, Pharmacogenetics.
[47] M A Butler,et al. Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps. , 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[48] S. W. Lee,et al. CYP1A2 activity as a risk factor for bladder cancer. , 1994, Journal of Korean medical science.
[49] Y Fujii-Kuriyama,et al. Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. , 1994, The Journal of biological chemistry.
[50] T. Tennenbaum,et al. Role of oncogenes and tumor suppressor genes in multistage carcinogenesis. , 1994, The Journal of investigative dermatology.
[51] J. Idle,et al. Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility. , 1994, Environmental health perspectives.
[52] E. Glover,et al. Analysis of the four alleles of the murine aryl hydrocarbon receptor. , 1994, Molecular pharmacology.
[53] G R Wilkinson,et al. Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. , 1994, Molecular pharmacology.
[54] S. Davis,et al. Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: A putative probe of CYP2E1 activity , 1994, Clinical pharmacology and therapeutics.
[55] M. Oshimura,et al. Human arylhydrocarbon receptor: functional expression and chromosomal assignment to 7p21. , 1994, Journal of biochemistry.
[56] G. Clark,et al. Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. , 1994, Pharmacogenetics.
[57] H. Hiroshi,et al. Biochemistry and molecular biology of drug-metabolizing sulfotransferase. , 1994 .
[58] C. Hassett,et al. The human microsomal epoxide hydrolase gene (EPHX1): complete nucleotide sequence and structural characterization. , 1994, Genomics.
[59] R. Branch,et al. Correlation of polymorphic expression of CYP2D6 mRNA in bladder mucosa and tumor tissue to in vivo debrisoquine hydroxylase activity. , 1994, Carcinogenesis.
[60] A. Rannug,et al. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. , 1994, Carcinogenesis.
[61] S. R. Babu,et al. Human liver glucuronidation of benzidine. , 1994, Carcinogenesis.
[62] J. Brockmöller,et al. Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study. , 1994, Cancer research.
[63] K. Kawajiri,et al. Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5'-flanking region. , 1994, Journal of biochemistry.
[64] W. Schulz,et al. Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line. , 1994, Biological chemistry Hoppe-Seyler.
[65] T. Kamataki,et al. Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. , 1994, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[66] H. Yamazaki,et al. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. , 1994, The Journal of pharmacology and experimental therapeutics.
[67] R. Kim,et al. Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazone: a putative measure of CYP2E1 activity. , 1994, Pharmacogenetics.
[68] B. Tang,et al. Caffeine as a probe for CYP1A2 activity: potential influence of renal factors on urinary phenotypic trait measurements. , 1994, Pharmacogenetics.
[69] U. Fuhr,et al. Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. , 1994, Pharmacogenetics.
[70] T. Nurminen,et al. Combined effect of CYP1A1 inducibility and GSTM1 polymorphism on histological type of lung cancer. , 1994, Carcinogenesis.
[71] C. Jefcoate,et al. Dual regulation of cytochrome P450EF expression via the aryl hydrocarbon receptor and protein stabilization in C3H/10T1/2 cells. , 1994, Molecular pharmacology.
[72] C. Jefcoate,et al. Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression. , 1994, The Journal of biological chemistry.
[73] Steven R. Tannenbaum,et al. Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens , 1994, Nature.
[74] D. Bernstein,et al. Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. , 1994, Carcinogenesis.
[75] O. Gotoh,et al. Interindividual difference in expression of human Ah receptor and related P450 genes. , 1994, Carcinogenesis.
[76] D. Thomas,et al. Methodological issues in the interpretation of studies of the CYP2D6 genotype in relation to lung cancer risk. , 1994, Pharmacogenetics.
[77] A. Brøgger,et al. Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls. , 1994, Pharmacogenetics.
[78] R. Kanamaru,et al. Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure. , 1994, Pharmacogenetics.
[79] J R Cashman,et al. The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. , 1994, Toxicology and applied pharmacology.
[80] D. Nebert,et al. 1462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent. , 1994, Pharmacogenetics.
[81] J. Idle,et al. Poor metabolisers of nicotine and CYP2D6 polymorphism , 1994, The Lancet.
[82] J. Miners,et al. The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases. , 1993, Carcinogenesis.
[83] S. Anttila,et al. Immunohistochemical localization of glutathione S-transferases in human lung. , 1993, Cancer research.
[84] A. Guillouzo,et al. Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone. , 1993, Chemical research in toxicology.
[85] H. Swanson,et al. The AH-receptor: genetics, structure and function. , 1993, Pharmacogenetics.
[86] E. Taioli,et al. Relationship between genotype and function of the human CYP1A1 gene. , 1993, Journal of toxicology and environmental health.
[87] N K Spurr,et al. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. , 1993, Carcinogenesis.
[88] W. Kalow. Pharmacogenetics: Its biologic roots and the medical challenge , 1993, Clinical pharmacology and therapeutics.
[89] W. Pearson,et al. Homozygous deletion of gene for glutathione S-transferase M1 in bladder cancer. , 1993, BMJ.
[90] W. Weber,et al. Individual variability in p-aminobenzoic acid N-acetylation by human N-acetyltransferase (NAT1) of peripheral blood. , 1993, Pharmacogenetics.
[91] E. Bowman,et al. Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes. , 1993, Cancer research.
[92] Jack A. Taylor,et al. Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. , 1993, Journal of the National Cancer Institute.
[93] H Vainio,et al. The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. , 1993, Carcinogenesis.
[94] K. Nakachi,et al. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. , 1993, Cancer research.
[95] W. Pearson,et al. Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13. , 1993, American journal of human genetics.
[96] D. Adler,et al. Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification. , 1993, Chemico-biological interactions.
[97] A. Lafuente,et al. Enhanced glutathione S-transferase activity and glutathione content in human bladder cancer. Followup study: influence of smoking. , 1993, The Journal of urology.
[98] D. Hémon,et al. Fundamentals of case-control studies. , 1993, Pharmacogenetics.
[99] N. Weiss,et al. The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma. , 1993, Cancer research.
[100] B. Tang,et al. The use of caffeine for enzyme assays: A critical appraisal , 1993, Clinical pharmacology and therapeutics.
[101] R. Hayes,et al. N-acetylation phenotype and genotype and risk of bladder cancer in benzidine-exposed workers. , 1993, Carcinogenesis.
[102] T. Iyanagi,et al. Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5'-diphosphate glucuronosyltransferases. , 1993, Cancer research.
[103] K. Kinzler,et al. The multistep nature of cancer. , 1993, Trends in genetics : TIG.
[104] D. Grant,et al. Role of polymorphic and monomorphic human arylamine N-acetyltransferases in determining sulfamethoxazole metabolism. , 1993, Biochemical pharmacology.
[105] J. Brockmöller,et al. Genotype and Phenotype of Glutathione S-Transferase Class µ Isoenzymes µ and ψ in Lung Cancer Patients and Controls , 1993 .
[106] M. Waters,et al. The genetic toxicology of putative nongenotoxic carcinogens. , 1993, Mutation research.
[107] W. Weber,et al. Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus. , 1993, Archives of biochemistry and biophysics.
[108] S. Anttila,et al. PCR-based CYP2D6 genotyping for Finnish lung cancer patients. , 1993, Pharmacogenetics.
[109] K. Nakachi,et al. The CYP1A1 gene and cancer susceptibility. , 1993, Critical reviews in oncology/hematology.
[110] D. Grant. Molecular genetics of the N-acetyltransferases. , 1993, Pharmacogenetics.
[111] A. Lafuente,et al. Human glutathione S-transferase mu (GST mu) deficiency as a marker for the susceptibility to bladder and larynx cancer among smokers. , 1993, Cancer letters.
[112] S. Yuspa,et al. Critical Aspects of Initiation, Promotion, and Progression in Multistage Epidermal Carcinogenesis , 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[113] S. Anttila,et al. Metabolic cytochrome P450 genotypes and assessment of individual susceptibility to lung cancer. , 1992, Pharmacogenetics.
[114] M A Butler,et al. Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis. , 1992, Environmental health perspectives.
[115] E. Bowman,et al. Polycyclic aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment length polymorphism. , 1992, Environmental health perspectives.
[116] G. Talaska,et al. The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer. , 1992, Environmental health perspectives.
[117] R. Kanamaru,et al. Human cytochrome P450IIE1 gene: DraI polymorphism and susceptibility to cancer. , 1992, The Tohoku journal of experimental medicine.
[118] C. Bradfield,et al. A brief review of the Ah locus. , 1992, The Tohoku journal of experimental medicine.
[119] O Pelkonen,et al. Interindividual variability of coumarin 7-hydroxylation in healthy volunteers. , 1992, Pharmacogenetics.
[120] S. Anttila,et al. Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. , 1992, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[121] K. Kawajiri,et al. High Susceptibility to Lung Cancer Analyzed in Terms of Combined Genotypes of P450IA1 and Mu‐class Glutathione S‐Transferase Genes , 1992, Japanese journal of cancer research : Gann.
[122] R. Branch,et al. The ability to 4-hydroxylate debrisoquine is related to recurrence of bladder cancer. , 1992, Pharmacogenetics.
[123] R. Hayes,et al. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. , 1992, Pharmacogenetics.
[124] C. Smith,et al. Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility. , 1992, Carcinogenesis.
[125] O. Hankinson,et al. Identification of the Ah Receptor Nuclear Translocator Protein (Arnt) as a Component of the DNA Binding Form of the Ah Receptor , 1992, Science.
[126] J. Idle,et al. Comparison of a novel thin-layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydroxycoumarin in human urine. , 1992, Journal of chromatography.
[127] W. Pearson,et al. Nomenclature for human glutathione transferases. , 1992, The Biochemical journal.
[128] K. Danenberg,et al. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. , 1992, Cancer research.
[129] Y. Fujii‐Kuriyama,et al. P450 and Human Cancer , 1991, Japanese journal of cancer research : Gann.
[130] B. Tang,et al. Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities , 1991, Clinical pharmacology and therapeutics.
[131] D. Nebert,et al. Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin. , 1991, Pharmacogenetics.
[132] H. Kikuchi,et al. MspI polymorphism of the human CYP2E gene. , 1991, Nucleic acids research.
[133] K. Nakachi,et al. Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. , 1991, Cancer research.
[134] A. Brøgger,et al. Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. , 1991, Pharmacogenetics.
[135] K. Nakachi,et al. Genetic linkage of lung cancer-associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. , 1991, Journal of biochemistry.
[136] B. Vogelstein,et al. p53 mutations in human cancers. , 1991, Science.
[137] F. Gonzalez,et al. A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. , 1991, Carcinogenesis.
[138] T. Kamataki,et al. Two common RFLPs of the human CYP2E gene. , 1991, Nucleic acids research.
[139] J. Dalphin,et al. Lack of a relationship between the polymorphism of debrisoquine oxidation and lung cancer. , 1991, British journal of clinical pharmacology.
[140] W. Halperin,et al. Excess number of bladder cancers in workers exposed to ortho-toluidine and aniline. , 1991, Journal of the National Cancer Institute.
[141] D. Nebert,et al. Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP. , 1991, American journal of human genetics.
[142] R. Kanamaru,et al. Association between Restriction Fragment Length Polymorphism of the Human Cytochrome P450IIE1 Gene and Susceptibility to Lung Cancer , 1991, Japanese journal of cancer research : Gann.
[143] F. Guengerich,et al. Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. , 1991, Chemical research in toxicology.
[144] M. Boyd,et al. Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. , 1990, Journal of the National Cancer Institute.
[145] F. Kadlubar,et al. Aromatic amine acetyltransferase as a marker for colorectal cancer: Environmental and demographic associations , 1990, International journal of cancer.
[146] T. Aoyama,et al. Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[147] K. Nakachi,et al. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene , 1990, FEBS letters.
[148] D. Nebert,et al. Evolution of the P450 gene superfamily and regulation of the murine Cyp1a1 gene. , 1990, Biochemical Society transactions.
[149] R. Hayes,et al. Lung cancer risk, occupational exposure, and the debrisoquine metabolic phenotype. , 1989, Cancer research.
[150] W. Pearson,et al. Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[151] F. Guengerich. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. , 1988, Cancer research.
[152] O. Mcbride,et al. A Taq I polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E). , 1987, Nucleic acids research.
[153] R. Branch,et al. Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors. , 1987, Cancer research.
[154] J. Groopman,et al. Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones. , 1987, Cancer research.
[155] F. Gonzalez,et al. Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat. , 1987, Molecular endocrinology.
[156] Ş. Şardaş,et al. N-Acetyltransferase Phenotype of Patients with Bladder Cancer , 1986, Human toxicology.
[157] D. Nebert,et al. Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues , 1986, Molecular and cellular biology.
[158] R. Pero,et al. A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer. , 1986, Carcinogenesis.
[159] R. Pero,et al. Hereditary interindividual differences in the glutathione transferase activity towards trans-stilbene oxide in resting human mononuclear leukocytes are due to a particular isozyme(s). , 1985, Carcinogenesis.
[160] M. Hetzel,et al. Metabolic oxidation phenotypes as markers for susceptibility to lung cancer , 1984, Nature.
[161] D. Grant,et al. A simple test for acetylator phenotype using caffeine. , 1984, British journal of clinical pharmacology.
[162] D. Evans,et al. The association of the slow acetylator phenotype with bladder cancer. , 1983, Journal of medical genetics.
[163] N P Wray,et al. Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes. , 1982, Cancer research.
[164] R. Glashan,et al. ROLE OF N-ACETYLTRANSFERASE PHENOTYPES IN BLADDER CARCINOGENESIS: A PHARMACOGENETIC EPIDEMIOLOGICAL APPROACH TO BLADDER CANCER , 1982, The Lancet.
[165] K. Steenland,et al. Seasonal variation of aryl hydrocarbon hydroxylase activity in human lymphocytes. , 1981, Cancer research.
[166] B. Paigen,et al. Induction, inhibition, and some enzymological properties of aryl hydrocarbon hydroxylase in fresh mitogen-activated human lymphocytes. , 1979, Cancer research.
[167] H. Wolf,et al. N-Acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark , 1979, Environmental health perspectives.
[168] K. Steenland,et al. Aryl hydrocarbon hydroxylase inducibility is not altered in bladder cancer patients or their progeny , 1979, International journal of cancer.
[169] K. Steenland,et al. Aryl hydrocarbon hydroxylase in persons with lung or laryngeal cancer , 1978, International journal of cancer.
[170] P. Kitzing,et al. ARYL HYDROCARBON HYDROXYLASE INDUCIBILITY AND CARCINOMA OF ORAL CAVITY , 1978, The Lancet.
[171] J. Idle,et al. POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN , 1977, The Lancet.
[172] B. Paigen,et al. Factors influencing the measurement and the reproducibility of aryl hydrocarbon hydroxylase activity in culutred human lymphocytes. , 1977, Journal of the National Cancer Institute.
[173] I. Bross,et al. Distribution of aryl hydrocarbon hydroxylase inducibility in cultured human lymphocytes. , 1977, Cancer research.
[174] P. Kitzing,et al. ARYL HYDROCARBON HYDROXYLASE INDUCIBILITY AND LARYNGEAL CARCINOMAS , 1976, The Lancet.
[175] C R Shaw,et al. Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma. , 1973, The New England journal of medicine.
[176] J. Groopman,et al. Molecular biomarkers for aflatoxins and their application to human liver cancer. , 1995, Pharmacogenetics.
[177] K. Kawajiri,et al. Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility. , 1995, Pharmacogenetics.
[178] J. Ritter,et al. Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation. , 1995, Progress in nucleic acid research and molecular biology.
[179] K. Noda,et al. Distribution of GSTM1 null genotype in relation to gender, age and smoking status in Japanese lung cancer patients. , 1995, Pharmacogenetics.
[180] Li Fp. Translational research on hereditary colon, breast, and ovarian cancers. , 1995 .
[181] C. Michejda,et al. Carcinogen activation by sulfate conjugate formation. , 1994, Advances in pharmacology.
[182] J. Idle,et al. Pharmacogenetic Phenotyping and Genotyping , 1994, Clinical pharmacokinetics.
[183] T. Xie,et al. NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer. , 1994, Oncology research.
[184] Y. Fujii‐Kuriyama,et al. Ah receptor: a novel ligand-activated transcription factor. , 1994, Experimental and clinical immunogenetics.
[185] D. Currie,et al. Racial differences in restriction fragment length polymorphisms and messenger RNA inducibility of the human CYP1A1 gene. , 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[186] D. Adler,et al. The molecular basis of the human serum paraoxonase activity polymorphism , 1993, Nature Genetics.
[187] R. Branch,et al. Bladder cancer recurrence and its association with cytochrome P-450IID6 activity. , 1992, Progress in clinical and biological research.
[188] D. Eaton,et al. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione. , 1992, Carcinogenesis.
[189] Lang Np,et al. Aromatic and heterocyclic amine metabolism and phenotyping in humans. , 1991 .
[190] Y. Horsmans,et al. Is there a link between debrisoquine oxidation phenotype and lung cancer susceptibility? , 1991, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[191] A. Llerena,et al. Polymorphic oxidation of debrisoquine in lung cancer patients. , 1991, European journal of cancer.
[192] F. Gonzalez,et al. Activation of promutagens by human cDNA-expressed cytochrome P450s. , 1990, Progress in clinical and biological research.
[193] K. Nakachi,et al. Individual differences in lung cancer susceptibility in relation to polymorphisms of P-450IA1 gene and cigarette dose. , 1990, Princess Takamatsu symposia.
[194] B. Ketterer,et al. The role of glutathione and glutathione transferases in chemical carcinogenesis. , 1990, Critical reviews in biochemistry and molecular biology.
[195] D. Nebert,et al. Regulation of the mammalian cytochrome P1-450 (CYP1A1) gene. , 1989, The International journal of biochemistry.
[196] F. Guengerich. Cytochromes P-450. , 1988, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
[197] I. Roots,et al. Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk. , 1988, Klinische Wochenschrift.
[198] M. Eichelbaum. Polymorphic oxidation of debrisoquine and sparteine. , 1986, Progress in clinical and biological research.
[199] J. Idle,et al. Polymorphisms of oxidation at carbon centers of drugs and their clinical significance. , 1979, Drug metabolism reviews.