Precise characterisation of monoclonal antibodies to the C-terminal region of p53 protein using the PEPSCAN ELISA technique and a new non-radioactive gel shift assay.
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E. Paleček | V. Brázda | Š. Pospíšilová | B. Vojtesek | J. Amrichová | R. Kamermeierová | E. Paleček | B. Vojtêšek
[1] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[2] K. Novak. Tying-up tuberculosis , 2000, Nature Medicine.
[3] E. Paleček,et al. Effect of transition metals on binding of p53 protein to supercoiled DNA and to consensus sequence in DNA fragments , 1999, Oncogene.
[4] L. Bracco,et al. Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments , 1999, Oncogene.
[5] K. Aldape,et al. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[6] T. Jovin,et al. Tumor suppressor protein p53 binds preferentially to supercoiled DNA , 1997, Oncogene.
[7] W. Deppert,et al. DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53 , 1997, Oncogene.
[8] B. Groner,et al. Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain , 1997, Nature Medicine.
[9] N. Hynes,et al. Characterization of scFv-421, a single-chain antibody targeted to p53. , 1997, Biochemical and biophysical research communications.
[10] D. Lane,et al. Small peptides activate the latent sequence-specific DNA binding function of p53 , 1995, Cell.
[11] G. Stark,et al. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[12] D. Lane,et al. Two Distinct Signaling Pathways Activate the Latent DNA Binding Function of p53 in a Casein Kinase II-independent Manner (*) , 1995, Journal of Biological Chemistry.
[13] D. Lane,et al. Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions. , 1995, Journal of molecular biology.
[14] G. Marius Clore,et al. Refined solution structure of the oligomerization domain of the tumour suppressor p53 , 1995, Nature Structural Biology.
[15] N. Pavletich,et al. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms , 1995, Science.
[16] J. Kovarik,et al. p53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence. , 1995, Oncogene.
[17] J. Kovarik,et al. Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein. , 1995, Oncogene.
[18] A. Meyer,et al. Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein. , 1994, Oncogene.
[19] D. Lane,et al. Allosteric activation of latent p53 tetramers , 1994, Current Biology.
[20] T. Soussi,et al. Linear antigenic sites defined by the B-cell response to human p53 are localized predominantly in the amino and carboxy-termini of the protein. , 1994, Oncogene.
[21] D. Lane,et al. Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens. , 1994, Cancer research.
[22] A. Levine,et al. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. , 1994, Genes & development.
[23] K. Kinzler,et al. Sequence-specific transcriptional activation is essential for growth suppression by p53. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[24] J. E. Stenger,et al. p53 domains: identification and characterization of two autonomous DNA-binding regions. , 1993, Genes & development.
[25] X. Chen,et al. A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. , 1993, Genes & development.
[26] T. Halazonetis,et al. Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. , 1993, The EMBO journal.
[27] C. Pabo,et al. The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots. , 1993, Genes & development.
[28] D. Lane,et al. Activation of the cryptic DNA binding function of mutant forms of p53. , 1993, Nucleic acids research.
[29] V. Rotter,et al. Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. , 1993, Oncogene.
[30] C. Purdie,et al. Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.
[31] Scott W. Lowe,et al. p53 is required for radiation-induced apoptosis in mouse thymocytes , 1993, Nature.
[32] T. Halazonetis,et al. Wild‐type p53 adopts a ‘mutant’‐like conformation when bound to DNA. , 1993, The EMBO journal.
[33] J. Bartek,et al. Immunohtstochemical analysis of the p53 oncoprotein on paraffin sections using a series of novel monoclonal antibodies , 1993, The Journal of pathology.
[34] D. Lane,et al. Regulation of the specific DNA binding function of p53 , 1992, Cell.
[35] E. Appella,et al. Human wild-type p53 adopts a unique conformational and phosphorylation state in vivo during growth arrest of glioblastoma cells. , 1992, Oncogene.
[36] P. Meltzer,et al. Amplification of a gene encoding a p53-associated protein in human sarcomas , 1992, Nature.
[37] J. Bartek,et al. An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53. , 1992, Journal of immunological methods.
[38] K. Kinzler,et al. Definition of a consensus binding site for p53 , 1992, Nature Genetics.
[39] S. Fields,et al. Presence of a potent transcription activating sequence in the p53 protein. , 1990, Science.
[40] D. Lane,et al. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. , 1990, The EMBO journal.
[41] J. Milner,et al. The cellular tumour antigen p53: evidence for transformation-related, immunological variants of p53. , 1986, Virology.
[42] J. Yewdell,et al. Monoclonal antibody analysis of p53 expression in normal and transformed cells , 1986, Journal of virology.
[43] J. Milner. Different forms of p53 detected by monoclonal antibodies in non-dividing and dividing lymphocytes , 1984, Nature.
[44] D. Pim,et al. Monoclonal antibodies specific for simian virus 40 tumor antigens , 1981, Journal of virology.
[45] J. Kovarik,et al. Epitope analysis of the human p53 tumour suppressor protein. , 1997, Folia biologica.
[46] Thierry Soussi,et al. Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation , 1996, Nucleic Acids Res..
[47] J. Bartek,et al. Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli. , 1992, Journal of cell science.
[48] E. Harlow,et al. Antibodies: A Laboratory Manual , 1988 .