Morphological analysis of the papillary muscles and the trabeculae

High resolution cardiac CT imaging technology has revealed the complex endocardial structures of the left ventricle, such as the trabeculae and the papillary muscles. In this paper, we study the morphology of such complex structures. We represent the structures accurately and concisely using curve skeletons, and measure these structures using topological and geometrical features. It is observed both qualitatively and quantitatively that structures at different parts of the endocardial surface have different characteristics. This morphological study sheds light on the potential future use of these complex en-docardial structures to study cardiac function and to diagnose cardiac diseases.

[1]  Peter Hunold,et al.  Assessment of left ventricular parameters using 16-MDCT and new software for endocardial and epicardial border delineation. , 2005, AJR. American journal of roentgenology.

[2]  Rangasami L. Kashyap,et al.  Building Skeleton Models via 3-D Medial Surface/Axis Thinning Algorithms , 1994, CVGIP Graph. Model. Image Process..

[3]  Hui Wang,et al.  Cardiac Motion and Deformation Recovery From MRI: A Review , 2012, IEEE Transactions on Medical Imaging.

[4]  Tamal K. Dey,et al.  Defining and computing curve-skeletons with medial geodesic function , 2006, SGP '06.

[5]  E. McVeigh,et al.  Regional myocardial function. , 1998, Cardiology clinics.

[6]  Suchendra M. Bhandarkar,et al.  Morphological Analysis of the Left Ventricular Endocardial Surface and Its Clinical Implications , 2012, MICCAI.

[7]  Chao Chen,et al.  Segmenting the Papillary Muscles and the Trabeculae from High Resolution Cardiac CT through Restoration of Topological Handles , 2013, IPMI.

[8]  Scott Kulp,et al.  Using High Resolution Cardiac CT Data to Model and Visualize Patient-Specific Interactions between Trabeculae and Blood Flow , 2011, MICCAI.

[9]  Francis C. Wells.  Leonardo’s Heart , 2013 .

[10]  M. Cerqueira,et al.  Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. , 2002, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

[11]  M. Cerqueira,et al.  Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. , 2002, Circulation.

[12]  J M de Bakker,et al.  Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts. , 1994, Cardiovascular research.

[13]  Caroline Petitjean,et al.  A review of segmentation methods in short axis cardiac MR images , 2011, Medical Image Anal..

[14]  David A Bluemke,et al.  Regional myocardial function: advances in MR imaging and analysis. , 2003, Radiographics : a review publication of the Radiological Society of North America, Inc.

[15]  Marcel Breeuwer,et al.  Correlation of trabeculae and papillary muscles with clinical and cardiac characteristics and impact on CMR measures of LV anatomy and function. , 2012, JACC. Cardiovascular imaging.

[16]  Junzhou Huang,et al.  4D Cardiac Reconstruction Using High Resolution CT Images , 2011, FIMH.

[17]  Elliot R. McVeigh,et al.  A New Method for Cardiac Computed Tomography Regional Function Assessment: Stretch Quantifier for Endocardial Engraved Zones (SQUEEZ) , 2012, Circulation. Cardiovascular imaging.

[18]  Junzhou Huang,et al.  Papillary muscles analysis from high resolution CT using spatial-temporal skeleton extraction , 2013, 2013 IEEE 10th International Symposium on Biomedical Imaging.

[19]  M. Cerqueira,et al.  Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association , 2002, The international journal of cardiovascular imaging.

[20]  Herbert Edelsbrunner,et al.  Computational Topology - an Introduction , 2009 .

[21]  J. Laidlaw,et al.  ANATOMY OF THE HUMAN BODY , 1967, The Ulster Medical Journal.