Fitting linear compartmental models by a matrix diagonalization method
暂无分享,去创建一个
A general method is presented for fitting experimental data to arbitrary linear compartmental models, based on readily available public domain software. The model is defined by input data so that the same program can be used for different compartmental models. Its use is exemplified by application to the four-compartment problem recently treated by Charkes and Siegel.
[1] R. Schoenfeld,et al. Invariants in Experimental Data on Linear Kinetics and the Formulation of Models , 1956 .
[2] P. J. Ebertein,et al. A Jacobi-Like Method for the Automatic Computation of Eigenvalues and Eigenvectors of an Arbitrary Matrix , 1962 .
[3] John E. Dennis,et al. Algorithm 573: NL2SOL—An Adaptive Nonlinear Least-Squares Algorithm [E4] , 1981, TOMS.
[4] J. Siegel,et al. An analytical solution set for a four-compartment mixed mammillary/catenary model. , 1999, Nuclear medicine communications.