Effects of Sleep Debt on Cognitive Performance and Prefrontal Activity in Humans

Functional neuroimaging is universally recognized to be a remarkably effective modality for exploring precise brain function. Functional magnetic resonance imaging (fMRI) and positron-emission tomography (PET) are among the most widely used neuroimaging techniques; however, their invasiveness in terms of, for example, exposure to high magnetic fields or radiation, or restriction of body movement during the examination, makes their application difficult in infants, children, and some subjects with an atypical condition.

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