A Study on Seizure Detection of EEG Signals Represented in 2D

A seizure is a neurological disorder caused by abnormal neuronal discharges in the brain, which severely reduces the quality of life of patients and often endangers their lives. Automatic seizure detection is an important research area in the treatment of seizure and is a prerequisite for seizure intervention. Deep learning has been widely used for automatic detection of seizures, and many related research works decomposed the electroencephalogram (EEG) raw signal with a time window to obtain EEG signal slices, then performed feature extraction on the slices, and represented the obtained features as input data for neural networks. There are various methods for EEG signal decomposition, feature extraction, and representation, and most of the studies have been based on fixed hardware resources for the design of the scheme, which reduces the adaptability of the scheme in different application scenarios and makes it difficult to optimize the algorithms in the scheme. To address the above issues, this paper proposes a deep learning-based model for seizure detection, mainly characterized by the two-dimensional representation of EEG features and the scalability of neural networks. The model modularizes the main steps of seizure detection and improves the adaptability of the model to different hardware resource constraints, in order to increase the convenience of the algorithm optimization or the replacement of each module. The proposed model consists of five parts, and the model was tested using two epilepsy datasets separately. The experimental results showed that the proposed model has strong generality and good classification accuracy for seizure detection.

[1]  Michalis E. Zervakis,et al.  A Long Short-Term Memory deep learning network for the prediction of epileptic seizures using EEG signals , 2018, Comput. Biol. Medicine.

[2]  Jiaming Zhang,et al.  EEG Emotion Classification Using an Improved SincNet-Based Deep Learning Model , 2019, Brain sciences.

[3]  G. Dumont,et al.  Predicting temporal lobe epileptic seizures based on zero-crossing interval analysis in scalp EEG , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[4]  Quoc V. Le,et al.  EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks , 2019, ICML.

[5]  Kebin Jia,et al.  FusionAtt: Deep Fusional Attention Networks for Multi-Channel Biomedical Signals , 2019, Sensors.

[6]  J. T. Turner,et al.  Deep Belief Networks used on High Resolution Multichannel Electroencephalography Data for Seizure Detection , 2017, AAAI Spring Symposia.

[7]  François Laviolette,et al.  Domain-Adversarial Training of Neural Networks , 2015, J. Mach. Learn. Res..

[8]  Yong Wang Classification of Epileptic Electroencephalograms Signals Using Combining Wavelet Analysis and Support Vector Machine , 2018 .

[9]  J. E. Jacob,et al.  Diagnosis of Encephalopathy Based on Energies of EEG Subbands Using Discrete Wavelet Transform and Support Vector Machine , 2018, Neurology research international.

[10]  Sridha Sridharan,et al.  Deep Classification of Epileptic Signals , 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[11]  Aydin Akan,et al.  Epileptic EEG Classification by Using Time-Frequency Images for Deep Learning , 2021, Int. J. Neural Syst..

[12]  George I. Lambrou,et al.  Signal2Image Modules in Deep Neural Networks for EEG Classification , 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[13]  Ali H. Shoeb,et al.  Application of machine learning to epileptic seizure onset detection and treatment , 2009 .

[14]  Fabio Babiloni,et al.  InstanceEasyTL: An Improved Transfer-Learning Method for EEG-Based Cross-Subject Fatigue Detection , 2020, Sensors.

[15]  Andreas T. Güntner,et al.  Guiding Ketogenic Diet with Breath Acetone Sensors , 2018, Sensors.

[16]  Amir F. Atiya,et al.  Epileptic Seizures Detection Using Deep Learning Techniques: A Review , 2020, International journal of environmental research and public health.

[17]  Toshihisa Tanaka,et al.  Localization of Epileptic Foci by Using Convolutional Neural Network Based on iEEG , 2019, AIAI.

[18]  John Thomas,et al.  EEG CLassification Via Convolutional Neural Network-Based Interictal Epileptiform Event Detection , 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[19]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[20]  Mehmet Siraç Özerdem,et al.  Epilepsy Detection by Using Scalogram Based Convolutional Neural Network from EEG Signals , 2019, Brain Science.

[21]  Si Thu Aung,et al.  Modified-Distribution Entropy as the Features for the Detection of Epileptic Seizures , 2020, Frontiers in Physiology.

[22]  U. Rajendra Acharya,et al.  Deep convolutional neural network for the automated detection and diagnosis of seizure using EEG signals , 2017, Comput. Biol. Medicine.

[23]  Concetto Spampinato,et al.  Deep Learning Provides Exceptional Accuracy to ECoG-Based Functional Language Mapping for Epilepsy Surgery , 2018, bioRxiv.

[24]  Yong Zhang,et al.  EEG-based classification of emotions using empirical mode decomposition and autoregressive model , 2018, Multimedia Tools and Applications.

[25]  R. Lavanya,et al.  Auto-encoder Based Automated Epilepsy Diagnosis , 2018, 2018 International Conference on Advances in Computing, Communications and Informatics (ICACCI).

[26]  Hao Wang,et al.  A source location privacy protection scheme based on ring-loop routing for the IoT , 2019, Comput. Networks.

[27]  Reda A. El-Khoribi,et al.  Emotion Recognition based on EEG using LSTM Recurrent Neural Network , 2017 .

[28]  Yanli Yang,et al.  Epileptic Seizure Prediction Based on Permutation Entropy , 2018, Front. Comput. Neurosci..

[29]  Jong-Wha Chong,et al.  A Novel Multi-scale 3D CNN with Deep Neural Network for Epileptic Seizure Detection , 2019, 2019 IEEE International Conference on Consumer Electronics (ICCE).

[30]  Saeid Sanei,et al.  Detection of Interictal Discharges With Convolutional Neural Networks Using Discrete Ordered Multichannel Intracranial EEG , 2017, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[31]  Yogendra Kumar Mishra,et al.  Biosensors for Epilepsy Management: State-of-Art and Future Aspects , 2019, Sensors.

[32]  Junzhong Zou,et al.  Automatic epileptic EEG detection using convolutional neural network with improvements in time-domain , 2019, Biomed. Signal Process. Control..

[33]  Clinton Fookes,et al.  Deep facial analysis: A new phase I epilepsy evaluation using computer vision , 2018, Epilepsy & Behavior.

[34]  J. Gotman Automatic recognition of epileptic seizures in the EEG. , 1982, Electroencephalography and clinical neurophysiology.

[35]  Xuhui Chen,et al.  Cost-Sensitive Deep Active Learning for Epileptic Seizure Detection , 2018, BCB.

[36]  Kebin Jia,et al.  A Multi-View Deep Learning Framework for EEG Seizure Detection , 2019, IEEE Journal of Biomedical and Health Informatics.

[37]  Tao Zhang,et al.  AR based quadratic feature extraction in the VMD domain for the automated seizure detection of EEG using random forest classifier , 2017, Biomed. Signal Process. Control..

[38]  U. Rajendra Acharya,et al.  A deep convolutional neural network model for automated identification of abnormal EEG signals , 2018, Neural Computing and Applications.

[39]  Guojun Dai,et al.  EEG classification of driver mental states by deep learning , 2018, Cognitive Neurodynamics.

[40]  Boualem Boashash,et al.  A Multistage System for Automatic Detection of Epileptic Spikes , 2018, REV Journal on Electronics and Communications.

[41]  K Lehnertz,et al.  Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: dependence on recording region and brain state. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[42]  Seok-Woo Jang,et al.  Detection of Epileptic Seizures Using Wavelet Transform, Peak Extraction and PSR from EEG Signals , 2020, Symmetry.

[43]  Arshad Jhumka,et al.  A decision theoretic framework for selecting source location privacy aware routing protocols in wireless sensor networks , 2018, Future Gener. Comput. Syst..

[44]  Navid Ghassemi,et al.  Epileptic seizures detection in EEG signals using TQWT and ensemble learning , 2019, 2019 9th International Conference on Computer and Knowledge Engineering (ICCKE).

[45]  U. Rajendra Acharya,et al.  Deep convolutional neural network for the automated diagnosis of congestive heart failure using ECG signals , 2018, Applied Intelligence.

[46]  Rabab K. Ward,et al.  Epileptic Seizure Detection: A Deep Learning Approach , 2018, 1803.09848.

[47]  Jianguo Liu,et al.  Deep Learning Classification for Epilepsy Detection Using a Single Channel Electroencephalography (EEG) , 2019, ICDLT.

[48]  Chen Chen,et al.  Classification of single-channel EEG signals for epileptic seizures detection based on hybrid features , 2018, Technology and health care : official journal of the European Society for Engineering and Medicine.

[49]  Marimuthu Palaniswami,et al.  Detection of epileptic seizure based on entropy analysis of short-term EEG , 2018, PloS one.

[50]  Yusuf Uzzaman Khan,et al.  Seizure prediction using statistical dispersion measures of intracranial EEG , 2014, Biomed. Signal Process. Control..