Progressive kidney damage after non-obstructive urinary tract infection.

abnormal signs resolved in part during the next two months, after which he was discharged to another hospital. The cerebrospinal fluid on day 7 contained 30 lymphocytes/ mm3, 2,200 R.B.C./mm3, and 70 mg protein/100 ml; on day 19, 263 lymphocytes/mm3 and 130 mg protein/100 ml; and on day 102, 8 lymphocytes/mm3 and 80 mg protein/100 ml. Cells from the lumbar cerebrospinal fluid were examined for H. hominis antigens and immunoglobulins by indirect immunofluorescence. In the first sample (day 31) there were plentiful mononuclear cells; about 15% contained H. hominis antigens and 20% contained IgG or IgM. A subsequent specimen (day 53) showed only small numbers of IgG-containing cells, and no H. hominis antigens were detected. H. hominis was isolated from the cerebrospinal fluid taken on day 7; this finding was not available until late in the illness. The serum titre to H. hominis rose from 1: 8 on day 3 to 1: 80 on day 53. On admission to this hospital the electroencephalogram was diffusely slow without periodic complexes. Over the next three days it deteriorated as the small amount of alpha rhythm disappeared; it then slowly improved, to become normal two months later.