The Long-Term Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia
暂无分享,去创建一个
L. Reeskamp | P. Banerjee | J. Kastelein | R. Pordy | Kuo-Chen Chan | J. Mcginniss | N. Khilla | Robert S. Rosenson | F. J. Raal | Paolo Rubba | P. B. Duell | Masahiro Koseki | E. Stroes | Shazia Ali | Yi Zhang | Daniel Gaudet
[1] G. Francis,et al. Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study , 2022, The Lancet.
[2] E. Fabris,et al. Lipid-Lowering Drug Therapy: Critical Approach for Implementation in Clinical Practice , 2021, American Journal of Cardiovascular Drugs.
[3] R. Rosenson. Existing and emerging therapies for the treatment of familial hypercholesterolemia , 2021, Journal of lipid research.
[4] D. Rader,et al. ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report , 2021, Arteriosclerosis, thrombosis, and vascular biology.
[5] Tom R. Gaunt,et al. ANNALS EXPRESS: Establishing reference intervals for triglyceride containing lipoprotein sub-fraction metabolites measured using Nuclear Magnetic Resonance Spectroscopy in a UK population. , 2020, Annals of clinical biochemistry.
[6] D. Gaudet,et al. Evinacumab for Homozygous Familial Hypercholesterolemia. , 2020, The New England journal of medicine.
[7] Jonathan C. Cohen,et al. Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance , 2020, Journal of Lipid Research.
[8] D. Gaudet,et al. Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity , 2019, Arteriosclerosis, thrombosis, and vascular biology.
[9] Daniel E Forman,et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. , 2019, Journal of the American College of Cardiology.
[10] L. Tokgozoglu,et al. Clinical management, psychosocial characteristics, and quality of life in patients with homozygous familial hypercholesterolemia undergoing LDL-apheresis in Turkey: Results of a nationwide survey (A-HIT1 registry). , 2019, Journal of clinical lipidology.
[11] R. Hegele,et al. Lipid-Lowering Agents. , 2019, Circulation research.
[12] M. Doumas,et al. Drugs that Mimic the Effect of Gene Mutations for the Prevention or the Treatment of Atherosclerotic Disease: From PCSK9 Inhibition to ANGPTL3 Inactivation. , 2019, Current pharmaceutical design.
[13] L. Donini,et al. Metabolomic signature of angiopoietin-like protein 3 deficiency in fasting and postprandial state , 2018, bioRxiv.
[14] F. Raal,et al. Familial hypercholesterolemia treatments: Guidelines and new therapies. , 2018, Atherosclerosis.
[15] R. Santos. Expression of LDLRs (Low-Density Lipoprotein Receptors), Dyslipidemia Severity, and Response to PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Inhibition in Homozygous Familial Hypercholesterolemia: Connecting the Dots. , 2018, Arteriosclerosis, thrombosis, and vascular biology.
[16] M. Davidson,et al. PCSK9 Inhibitors: Mechanism of Action, Efficacy, and Safety. , 2018, Reviews in cardiovascular medicine.
[17] J. Tu,et al. Estimating the prevalence of heterozygous familial hypercholesterolaemia: a systematic review and meta-analysis , 2017, BMJ Open.
[18] R. Hegele,et al. Lomitapide for the treatment of hypercholesterolemia , 2017, Expert opinion on pharmacotherapy.
[19] Tanya M. Teslovich,et al. Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease , 2017, The New England journal of medicine.
[20] Lale Tokgözoğlu,et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel , 2017, European heart journal.
[21] J. Danesh,et al. ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. , 2017, Journal of the American College of Cardiology.
[22] C. Shoulders,et al. HEART UK statement on the management of homozygous familial hypercholesterolaemia in the United Kingdom. , 2016, Atherosclerosis.
[23] R. Nordyke,et al. Systematic Review of Low‐Density Lipoprotein Cholesterol Apheresis for the Treatment of Familial Hypercholesterolemia , 2016, Journal of the American Heart Association.
[24] A. Rodday,et al. Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES) , 2016, Circulation.
[25] M. Jauhiainen,et al. The role of ANGPTL3 in controlling lipoprotein metabolism , 2016, Endocrine.
[26] J. Mckenney,et al. Effect of PCSK9 Inhibition by Alirocumab on Lipoprotein Particle Concentrations Determined by Nuclear Magnetic Resonance Spectroscopy , 2015, Journal of the American Heart Association.
[27] G. Watts,et al. Challenges in the Diagnosis and Treatment of Homozygous Familial Hypercholesterolemia , 2015, Drugs.
[28] Jonathan C. Cohen,et al. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys1[S] , 2015, Journal of Lipid Research.
[29] E. Bruckert. Recommendations for the management of patients with homozygous familial hypercholesterolaemia: overview of a new European Atherosclerosis Society consensus statement. , 2014, Atherosclerosis. Supplements.
[30] J. Borén,et al. Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society , 2014, Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
[31] R. Rosenson,et al. Systematic Review: Evaluating the Effect of Lipid-Lowering Therapy on Lipoprotein and Lipid Values , 2013, Cardiovascular Drugs and Therapy.
[32] M. McGowan. Emerging low-density lipoprotein (LDL) therapies: Management of severely elevated LDL cholesterol--the role of LDL-apheresis. , 2013, Journal of clinical lipidology.
[33] D. Gaudet,et al. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study , 2013, The Lancet.
[34] Samia Mora,et al. Clinical implications of discordance between low-density lipoprotein cholesterol and particle number. , 2011, Journal of clinical lipidology.
[35] Jonathan C. Cohen,et al. Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. , 2010, The New England journal of medicine.
[36] W. Cromwell,et al. Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy. , 2006, Clinics in laboratory medicine.
[37] M. Matsuda,et al. Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[38] C. Fraser,et al. Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. , 2005, Endocrinology.
[39] A. Jenkins,et al. Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. , 2003, Diabetes.
[40] F. Raal,et al. Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab , 2018, Arteriosclerosis, thrombosis, and vascular biology.
[41] P. Duell,et al. Low-Density Lipoprotein (LDL) Apheresis , 2015 .
[42] Yosuke Ando,et al. Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity. , 2006, Experimental animals.