D-Optimal Designs for Dynamic Models. Part II. Applications.

Abstract : In a preceding report (D-Optimal Designs For Dynamic Models, Part 1) some results on the theory of C-constrained D-optimal designs were presented. The present report is intended to be an illustration of the methods proposed: the consideration of different examples raises some interesting questions and remarks concerning both the theoretical situation considered in the previous report and the possible applications. The numerical methods developed in relation with the notion of D-optimality allow for a greater flexibility in judging the overall quality of a design, suggesting the need for a more general theory. (Author Modified Abstract)