Ascorbic acid inhibits covalent binding of enzymatically generated 2-acetyl-aminofluororene-N-sulfate to DNA under conditions in which it increases mutagenesis in salmonella TA-1538.

[1]  D. Jerina,et al.  Tentative identification of benzo[a]pyrene metabolite-nucleoside complexes produced in vitro by mouse liver microsomes. , 1978, Molecular pharmacology.

[2]  W. Allaben,et al.  Role of arylhydroxamic acid acyltransferase in the mutagenicity of N-hydroxy-N-2-fluorenylacetamide in Salmonella typhimurium. , 1978, Cancer research.

[3]  W. L. Nelson,et al.  Role of sulfotransferase from rat liver in the mutagenicity of N-hydroxy-2-acetylaminofluorene in Salmonella typhimurium , 1977 .

[4]  J R Gillette,et al.  Generation of reactive metabolites of N-hydroxy-phenacetin by glucoronidation and sulfation. , 1977, Biochemical pharmacology.

[5]  S. Thorgeirsson,et al.  Genetic differences in 2-acetylaminofluorene mutagenicity in vitro associated with mouse hepatic aryl hydrocarbon hydroxylase activity induced by polycyclic aromatic compounds. , 1976, Molecular pharmacology.

[6]  D. Schulte‐Frohlinde,et al.  Phosphate ester cleavage in ribose-5-phosphate induced by OH radicals in deoxygenated aqueous solution. The effect of Fe(II) and Fe(III) ions. , 1976, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[7]  D. Mcgregor.  The relationship of 2-acetamidofluorene mutagenicity in plate tests with its in vivo liver cell component distribution and its carcinogenic potential. , 1975, Mutation research.

[8]  B. Ames,et al.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. , 1975, Mutation research.

[9]  C. Sonntag,et al.  Radiation Chemistry of DNA-model Compounds , 1974 .

[10]  W. Baird,et al.  Isolation of the hydrocarbon-deoxyribonucleoside products from the DNA of mouse embryo cells treated in culture with 7-methylbenz(a)anthracene-3H. , 1973, Cancer research.

[11]  E. Kriek.  Persistent binding of a new reaction product of the carcinogen N-hydroxy-N-2-acetylaminofluorene with guanine in rat liver DNA in vivo. , 1972, Cancer research.

[12]  J. Miller,et al.  N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver. , 1970, Cancer research.

[13]  J A Miller,et al.  Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture. , 1970, Cancer research.

[14]  J. Miller,et al.  Reactivity in vivo of the Carcinogen N-Hydroxy-2-acetylaminofluorene: Increase by Sulfate Ion , 1970, Science.

[15]  C. Irving,et al.  Persistent binding of 2-acetylaminofluorene to rat liver DNA in vivo and consideration of the mechanism of binding of N-hydroxy-2-acetylaminofluorene to rat liver nucleic acids. , 1969, Cancer research.

[16]  S. Tandon,et al.  Preparation and Properties of Some N-Aryl Hydroxamic Acids. , 1962 .

[17]  D. Stout,et al.  N'-hydroxy-2-aminofluorene: the principal mutagen produced from N-hydroxy-2-acetylaminofluorene by a mammalian supernatant enzyme preparation. , 1976, Cancer letters.

[18]  J. Miller,et al.  8-(N-2-fluorenylacetamido)guanosine, an arylamidation reaction product of guanosine and the carcinogen N-acetoxy-N-2-fluorenylacetamide in neutral solution. , 1967, Biochemistry.