Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: an in vivo model for the analysis of igf function in the brain.

[1]  D. Clemmons,et al.  Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression. , 1994, Endocrinology.

[2]  M. Gallagher,et al.  Expression of insulin‐like growth factor binding protein‐4 and ‐5 mRNAs in adult rat forebrain , 1994, The Journal of comparative neurology.

[3]  L. Powell-Braxton,et al.  IGF-I is required for normal embryonic growth in mice. , 1993, Genes & development.

[4]  S. D’Mello,et al.  Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[5]  C. Bondy,et al.  Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[6]  D. Clemmons,et al.  Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[7]  T. Wood,et al.  Tissue-specific expression of the insulin-like growth factor binding protein (IGFBP) mRNAs in mouse and rat development , 1993, Regulatory Peptides.

[8]  J. Baker,et al.  Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) , 1993, Cell.

[9]  Elizabeth J. Robertson,et al.  Role of insulin-like growth factors in embryonic and postnatal growth , 1993, Cell.

[10]  C. Conover,et al.  Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1 , 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[11]  G. Werther,et al.  Olfactory bulb organ culture is supported by combined insulin-like growth factor-I and basic fibroblast growth factor , 1993, Brain Research.

[12]  S. Chernausek,et al.  Localization of insulin‐like growth factor binding protein‐4 expression in the developing and adult rat brain: Analysis by in situ hybridization , 1993, Journal of neuroscience research.

[13]  M. Carson,et al.  Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice , 1993, Neuron.

[14]  P. Backeljauw,et al.  Synthesis and regulation of insulin-like growth factor binding protein-5 in FRTL-5 cells. , 1993, Endocrinology.

[15]  C. Bondy,et al.  Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: Correlation with insulin-like growth factors I and II , 1993, Neuroscience.

[16]  F. Sánchez‐Franco,et al.  Immunocytochemical localization of insulin-like growth factor I in the hypothalamo-hypophyseal system of the adult rat. , 1992, Neuroendocrinology.

[17]  V. Han,et al.  Insulin-like growth factor-II (IGF-II) messenger ribonucleic acid is expressed in steroidogenic cells of the developing ovine adrenal gland: evidence of an autocrine/paracrine role for IGF-II. , 1992, Endocrinology.

[18]  I. Torres-Aleman,et al.  Basic fibroblast growth factor modulates insulin-like growth factor-I, its receptor, and its binding proteins in hypothalamic cell cultures. , 1992, Endocrinology.

[19]  J. Lauder,et al.  S‐100β and insulin‐like growth factor‐II differentially regulate growth of developing serotonin and dopamine neurons in vitro , 1992, Journal of neuroscience research.

[20]  V. Han,et al.  Mitogenic activity of epidermal growth factor on newborn rat astroglia: interaction with insulin-like growth factors. , 1992, Endocrinology.

[21]  S. Pons,et al.  Survival of Purkinje Cells in Cerebellar Cultures is Increased by Insulin‐like Growth Factor I , 1992, The European journal of neuroscience.

[22]  Shin-ichiro Takahashi,et al.  Creation of an autocrine model of insulin-like growth factor-I action in transfected FRTL-5 cells. , 1992, Endocrinology.

[23]  X. -. Li,et al.  Expression of IGF-1 mRNA in the murine subventricular zone during postnatal development. , 1992, Brain research. Molecular brain research.

[24]  P. Gluckman,et al.  A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury. , 1992, Biochemical and biophysical research communications.

[25]  D. Baskin,et al.  Effect of paraformaldehyde fixation on localization and characterization of insulin‐like growth factor‐I (IGF‐I) receptors in the rat brain , 1991, The Anatomical record.

[26]  F. Mcmorris,et al.  Insulin‐like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures , 1991, Journal of neuroscience research.

[27]  I. Torres-Aleman,et al.  Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain , 1991, Brain Research.

[28]  R. Osathanondh,et al.  mRNAs for insulin-like growth factor-II (IGF-II) and variant IGF-II are co-expressed in human fetal ovary and uterus , 1991, Molecular and Cellular Endocrinology.

[29]  X. -. Li,et al.  Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development. , 1991, Developmental biology.

[30]  D. Clemmons,et al.  Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Harvey,et al.  Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[32]  N. Ling,et al.  Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6). , 1991, Progress in growth factor research.

[33]  I. Torres-Aleman,et al.  Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture , 1990, Neuroscience.

[34]  M. Mizobuchi,et al.  Insulin-like growth factor I (IGF-I) distribution in the tissue and extracellular compartment in different regions of rat brain , 1990, Brain Research.

[35]  H. Werner,et al.  Cellular pattern of insulin-like growth factor-I (IGF-I) and type I IGF receptor gene expression in early organogenesis: comparison with IGF-II gene expression. , 1990, Molecular endocrinology.

[36]  R. Palmiter,et al.  Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. , 1990, Endocrinology.

[37]  J. Pintar,et al.  Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis. , 1990, Development.

[38]  T. Wood,et al.  The expression pattern of an insulin-like growth factor (IGF)-binding protein gene is distinct from IGF-II in the midgestational rat embryo. , 1990, Molecular endocrinology.

[39]  I. Torres-Aleman,et al.  Trophic effects of basic fibroblast growth factor on fetal rat hypothalamic cells: interactions with insulin-like growth factor I. , 1990, Brain research. Developmental brain research.

[40]  K. Valentino,et al.  Developmental expression of insulin-like growth factor-II receptor immunoreactivity in the rat central nervous system. , 1990, Endocrinology.

[41]  D. Clemmons,et al.  Insulin‐like growth factor binding protein secretion by muscle cells: Effect of cellular differentiation and proliferation , 1988, Journal of cellular physiology.

[42]  D. Clemmons,et al.  Radioimmunoassay of a 26,000-dalton plasma insulin-like growth factor-binding protein: control by nutritional variables. , 1988, The Journal of clinical endocrinology and metabolism.

[43]  R. Palmiter,et al.  Growth enhancement of transgenic mice expressing human insulin-like growth factor I. , 1988, Endocrinology.

[44]  F. Mcmorris,et al.  Insulin‐like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro , 1988, Journal of neuroscience research.

[45]  K. Valentino,et al.  Structural and immunohistochemical characterization of insulin-like growth factor I and II receptors in the murine central nervous system. , 1988, Endocrinology.

[46]  J. Pintar,et al.  Pattern of the insulin-like growth factor II gene expression during rat embryogenesis. , 1988, Development.

[47]  L. Swanson,et al.  Neuronal Expression of chimeric genes in transgenic mice , 1988, Neuron.

[48]  M. T. Brewer,et al.  Cloning, characterization, and expression of a human insulin-like growth factor binding protein. , 1988, Biochemical and biophysical research communications.

[49]  K. Herrup,et al.  Meiotic expression of human ornithine transcarbamylase in the testes of transgenic mice , 1988, Molecular and cellular biology.

[50]  H. Hansson,et al.  Differing expression of insulin-like growth factor I in the developing and in the adult rat cerebellum. , 1988, Acta physiologica Scandinavica.

[51]  P. J. Brooks,et al.  Insulin-like growth factor II messenger ribonucleic acids are synthesized in the choroid plexus of the rat brain. , 1988, Molecular endocrinology.

[52]  D. Clemmons,et al.  An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[53]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[54]  R. Hammer,et al.  Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes , 1985, Nature.

[55]  T. Joh,et al.  Optimization of tyrosine hydroxylase immunocytochemistry in paraffin sections using pretreatment with proteolytic enzymes. , 1984, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[56]  R. Palmiter,et al.  Structure of mouse metallothionein-I gene and its mRNA , 1981, Nature.

[57]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.