Alkaline phosphatase as a reporter of cancerous transformation.

[1]  H. Weissig,et al.  Cloning and expression of the bovine intestinal alkaline phosphatase gene: biochemical characterization of the recombinant enzyme. , 1993, The Biochemical journal.

[2]  J. Millán,et al.  Molecular mechanism of uncompetitive inhibition of human placental and germ-cell alkaline phosphatase. , 1992, The Biochemical journal.

[3]  J. Millán,et al.  Site-directed mutagenesis and epitope-mapped monoclonal antibodies define a catalytically important conformational difference between human placental and germ cell alkaline phosphatase. , 1991, European journal of biochemistry.

[4]  J. Millán,et al.  Gly429 is the major determinant of uncompetitive inhibition of human germ cell alkaline phosphatase by L-leucine. , 1991, The Biochemical journal.

[5]  L. N. Wu,et al.  Collagen-binding proteins in collagenase-released matrix vesicles from cartilage. Interaction between matrix vesicle proteins and different types of collagen. , 1991, The Journal of biological chemistry.

[6]  M. Whyte,et al.  Alkaline phosphatase (tissue-nonspecific isoenzyme) is a phosphoethanolamine and pyridoxal-5'-phosphate ectophosphatase: normal and hypophosphatasia fibroblast study. , 1990, American journal of human genetics.

[7]  J. Millán,et al.  Genomic structure and comparison of mouse tissue-specific alkaline phosphatase genes. , 1990, Genomics.

[8]  D. Rappolee,et al.  Two alkaline phosphatase genes are expressed during early development in the mouse embryo. , 1990, Development.

[9]  W. Fishman On the importance of being (stereo) specific. , 1990, Clinica chimica acta; international journal of clinical chemistry.

[10]  H. Harris,et al.  The human alkaline phosphatases: what we know and what we don't know. , 1990, Clinica chimica acta; international journal of clinical chemistry.

[11]  Millán Jl Oncodevelopmental alkaline phosphatases: in search for a function. , 1990 .

[12]  K. Kodukula,et al.  Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[13]  M. Hofmann,et al.  Alkaline phosphatase isozymes in human testicular germ cell tumors, their precancerous stage, and three related cell lines. , 1989, Cancer research.

[14]  Millán Jl Oncodevelopmental expression and structure of alkaline phosphatase genes. , 1988 .

[15]  J. Millán,et al.  A putative functional domain of human placental alkaline phosphatase predicted from sequence comparisons. , 1988, The Biochemical journal.

[16]  J. Millán,et al.  Seminoma-derived Nagao isozyme is encoded by a germ-cell alkaline phosphatase gene. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[17]  S. Udenfriend,et al.  Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[18]  Y. Misumi,et al.  Biosynthesis of placental alkaline phosphatase and its post-translational modification by glycophospholipid for membrane-anchoring. , 1988, The Journal of biological chemistry.

[19]  A. Saltiel,et al.  Structural and functional roles of glycosyl-phosphatidylinositol in membranes. , 1988, Science.

[20]  I. Vergote,et al.  Placental alkaline phosphatase as a tumor marker in ovarian cancer , 1987, Obstetrics and gynecology.

[21]  W. Fishman,et al.  Oncotrophoblast gene expression: placental alkaline phosphatase. , 1987, Advances in cancer research.

[22]  J. Millán Molecular cloning and sequence analysis of human placental alkaline phosphatase. , 1986, The Journal of biological chemistry.

[23]  C. Silfverswärd,et al.  Eutopic expression of placental‐like alkaline phosphatase in testicular tumors , 1984, International journal of cancer.

[24]  W. Fishman,et al.  Newly established uterine cervical cancer cell line (SKG-III) with Regan isoenzyme, human chorionic gonadotropin beta-subunit, and pregnancy-specific beta 1-glycoprotein phenotypes. , 1983, Cancer research.

[25]  R. Mulivor,et al.  Differential inhibition of the products of the human alkaline phosphatase loci , 1978, Annals of human genetics.

[26]  W. Fishman,et al.  L-leucine, a specific inhibitor of a rare human placental alkaline phosphatase phenotype , 1976, Nature.

[27]  W. Fishman,et al.  CHARACTERIZATION OF TWO HELA SUBLINES: TCRC-1 PRODUCES REGAN ISOENZYME AND TCRC-2, NON-REGAN ISOENZYME , 1974, The Journal of cell biology.

[28]  K. Higashino,et al.  Studies on a variant alkaline phosphatase in sera of patients with hepatocellular carcinoma. , 1972, Clinica chimica acta; international journal of clinical chemistry.

[29]  Fishman Wh,et al.  Organ-specific inhibition of human alkaline phosphatase isoenzymes of liver, bone, intestine and placenta; L-phenylalanine, L-tryptophan and L homoarginine. , 1971 .

[30]  W. Fishman,et al.  Automated differential isoenzyme analysis. II. The fractionation of serum alkaline phosphatases into "liver", "intestinal" and "other" components. , 1971, Enzymologia.

[31]  W. Fishman,et al.  New observations on the Regan isoenzyme of alkaline phosphatase in cancer patients , 1971, Cancer.

[32]  W. Fishman,et al.  A serum alkaline phosphatase isoenzyme of human neoplastic cell origin. , 1968, Cancer research.

[33]  W. Fishman,et al.  On the mechanism of inhibition of intestinal alkaline phosphatase by L-phenylalanine. I. Kinetic studies. , 1966, The Journal of biological chemistry.