Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas.

[1]  E. Haura,et al.  Targeting epidermal growth factor receptor: central signaling kinase in lung cancer. , 2010, Biochemical pharmacology.

[2]  Frank McCormick,et al.  The molecular pathology of cancer , 2010, Nature Reviews Clinical Oncology.

[3]  Holger Sudhoff,et al.  Molecular targeted therapies in head and neck cancer - An update of recent developements - , 2010, Head & neck oncology.

[4]  E. van Marck,et al.  Detection of HPV and the role of p16INK4A overexpression as a surrogate marker for the presence of functional HPV oncoprotein E7 in colorectal cancer , 2010, BMC Cancer.

[5]  V. Georgoulias,et al.  Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer. , 2010, World journal of gastroenterology.

[6]  M. Procházka,et al.  Human papillomavirus in the etiology of head and neck carcinomas. , 2010, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.

[7]  F. Ondrey,et al.  Exons 19 and 21 of Epidermal Growth Factor Receptor Are Highly Conserved in Squamous Cell Cancer of the Head and Neck , 2010, International journal of otolaryngology.

[8]  Martin Görner,et al.  HPV & head and neck cancer: a descriptive update , 2009, Head & neck oncology.

[9]  M. Urashima,et al.  Prognostic significance of epidermal growth factor receptor phosphorylation and mutation in head and neck squamous cell carcinoma. , 2009, The oncologist.

[10]  P. Lambin,et al.  Binding of cetuximab to the EGFRvIII deletion mutant and its biological consequences in malignant glioma cells. , 2009, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[11]  A. Bozec,et al.  Emerging molecular targeted therapies in the treatment of head and neck cancer , 2009, Expert opinion on emerging drugs.

[12]  J. Christensen,et al.  The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma. , 2009, Cancer research.

[13]  T. Mitsudomi,et al.  Immunohistochemical analysis of phosphorylated epidermal growth factor receptor might provide a surrogate marker of EGFR mutation. , 2009, Lung cancer.

[14]  K. Cuschieri,et al.  Human Papillomavirus mRNA and p16 Detection as Biomarkers for the Improved Diagnosis of Cervical Neoplasia , 2008, Cancer Epidemiology Biomarkers & Prevention.

[15]  R. Grenman,et al.  Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma , 2008, Cancer science.

[16]  A. Cmelak,et al.  Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. , 2008, Journal of the National Cancer Institute.

[17]  M. Páez de la Cadena,et al.  Absence of Activating Mutations in the EGFR Kinase Domain in Spanish Head and Neck Cancer Patients , 2007, Tumor Biology.

[18]  R. Singal,et al.  EGFR targeting of solid tumors. , 2007, Cancer control : journal of the Moffitt Cancer Center.

[19]  Diane D. Liu,et al.  Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[20]  R. Rosell,et al.  Epidermal Growth Factor Receptor Activation: How Exon 19 and 21 Mutations Changed Our Understanding of the Pathway , 2006, Clinical Cancer Research.

[21]  M. Pierotti,et al.  Molecular and Cytogenetic Subgroups of Oropharyngeal Squamous Cell Carcinoma , 2006, Clinical Cancer Research.

[22]  Christine H Chung,et al.  Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  Jennifer L Hunt,et al.  Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting , 2006, Clinical Cancer Research.

[24]  M. Ozsahin,et al.  The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications , 2006, Radiation oncology.

[25]  I. Kovalszky,et al.  Prognostic significance of high-risk HPV status in advanced cervical cancers and pelvic lymph nodes. , 2006, Gynecologic oncology.

[26]  Koji Yoshimoto,et al.  Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. , 2005, The New England journal of medicine.

[27]  Suk Woo Nam,et al.  Somatic Mutations of EGFR Gene in Squamous Cell Carcinoma of the Head and Neck , 2005, Clinical Cancer Research.

[28]  J. Ferlay,et al.  Global Cancer Statistics, 2002 , 2005, CA: a cancer journal for clinicians.

[29]  S. Franceschi,et al.  Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review , 2005, Cancer Epidemiology Biomarkers & Prevention.

[30]  Roy S Herbst,et al.  Review of epidermal growth factor receptor biology. , 2004, International journal of radiation oncology, biology, physics.

[31]  Patricia L. Harris,et al.  Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.

[32]  M. Hoa,et al.  Amplification of wild-type K-ras promotes growth of head and neck squamous cell carcinoma. , 2002, Cancer research.

[33]  R. Day,et al.  Levels of TGF-α and EGFR Protein in Head and Neck Squamous Cell Carcinoma and Patient Survival , 1998 .

[34]  R. McLendon,et al.  Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. , 1995, Cancer research.

[35]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[36]  A. Marchevsky,et al.  Evaluation of EGFR abnormalities in patients with pulmonary adenocarcinoma: the need to test neoplasms with more than one method , 2009, Modern Pathology.

[37]  Z. Szentirmay,et al.  Human papillomavirus in head and neck cancer: Molecular biology and clinicopathological correlations , 2005, Cancer and Metastasis Reviews.

[38]  K. Harrington,et al.  Biological significance of c-erbB family oncogenes in head and neck cancer , 2005, Cancer and Metastasis Reviews.

[39]  Lajos Döbróssy,et al.  Epidemiology of head and neck cancer: Magnitude of the problem , 2005, Cancer and Metastasis Reviews.