On CK2 regulation of chronic lymphocytic leukemia cell viability

[1]  J. Gribben,et al.  Update on therapy of chronic lymphocytic leukemia. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  Richard Sherry,et al.  The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia. , 2011, Blood.

[3]  J. Barata,et al.  Targeting CK2 overexpression and hyperactivation as a novel therapeutic tool in chronic lymphocytic leukemia. , 2010, Blood.

[4]  U. Jaeger,et al.  Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia. , 2010, Blood.

[5]  J. Barata,et al.  Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and γ-secretase inhibitors , 2010, Haematologica.

[6]  M. Keating,et al.  B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406. , 2009, Blood.

[7]  K. Stamatopoulos,et al.  Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation , 2008, Journal of internal medicine.

[8]  J. Barata,et al.  PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability. , 2008, The Journal of clinical investigation.

[9]  C. Rehder,et al.  Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia , 2007, American journal of hematology.

[10]  J. Cheong,et al.  Protein Kinase CK2α as an Unfavorable Prognostic Marker and Novel Therapeutic Target in Acute Myeloid Leukemia , 2007, Clinical Cancer Research.

[11]  N. Varin‐Blank,et al.  Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression. , 2006, Cancer research.

[12]  G. Unger,et al.  Induction of apoptosis by antisense CK2 in human prostate cancer xenograft model. , 2004, Molecular cancer research : MCR.

[13]  P. Chiusolo,et al.  Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells. , 2004, Blood.

[14]  J. Plate PI3-Kinase Regulates Survival of Chronic Lymphocytic Leukemia B-Cells by Preventing Caspase 8 Activation , 2004, Leukemia & lymphoma.

[15]  F. Martín-Saavedra,et al.  A sustained activation of PI3K/NF-κB pathway is critical for the survival of chronic lymphocytic leukemia B cells , 2004, Leukemia.

[16]  C. Peschel,et al.  Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta. , 2002, Blood.

[17]  J. Barata The impact of PTEN regulation by CK2 on PI3K-dependent signaling and leukemia cell survival. , 2011, Advances in enzyme regulation.

[18]  H. Döhner,et al.  From pathogenesis to treatment of chronic lymphocytic leukaemia , 2010, Nature Reviews Cancer.

[19]  H. Döhner,et al.  Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids , 2007, Leukemia.

[20]  J. Cheong,et al.  Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia. , 2007, Clinical cancer research : an official journal of the American Association for Cancer Research.