Mouse models of congenital cataract

[1]  N. Klopp,et al.  Three murine cataract mutants (Cat2) are defective in different γ- crystallin genes , 1998 .

[2]  G. Mardon,et al.  Dachshund and Eyes Absent Proteins Form a Complex and Function Synergistically to Induce Ectopic Eye Development in Drosophila , 1997, Cell.

[3]  C. Desplan,et al.  Eye Development: Governed by a Dictator or a Junta? , 1997, Cell.

[4]  J. Graw,et al.  Cat3vl and Cat3vao cataract mutations on mouse chromosome 10: phenotypic characterization, linkage studies and analysis of candidate genes , 1997, Molecular and General Genetics MGG.

[5]  J. Murray,et al.  Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. , 1997, Human molecular genetics.

[6]  J. Graw The crystallins: genes, proteins and diseases. , 1997, Biological chemistry.

[7]  A. Grinberg,et al.  The Rx homeobox gene is essential for vertebrate eye development , 1997, Nature.

[8]  W. Bickmore,et al.  The reticulocalbin gene maps to the WAGR region in human and to the Small eye Harwell deletion in mouse. , 1997, Genomics.

[9]  M. Lyon,et al.  Identification of a mutation in the MP19 gene, Lim2, in the cataractous mouse mutant To3. , 1997, Molecular vision.

[10]  C. Cepko,et al.  rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[11]  J. Graw,et al.  Effects of UV-B radiation on a hereditary suture cataract in mice. , 1997, Experimental eye research.

[12]  P. Gruss,et al.  Ectopic lens induction in fish in response to the murine homeobox gene Six3 , 1996, Mechanisms of Development.

[13]  P. Gruss,et al.  Pax2 contributes to inner ear patterning and optic nerve trajectory. , 1996, Development.

[14]  P. Beachy,et al.  Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function , 1996, Nature.

[15]  T. Kamoto,et al.  Mapping of rupture of lens cataract (rlc) on mouse chromosome 14. , 1996, Genomics.

[16]  M. Lyon,et al.  Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse. , 1996, Genomics.

[17]  E. Rogaev,et al.  Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. , 1996, Human molecular genetics.

[18]  S. Bassnett,et al.  Mutations in the founder of the MIP gene family underlie cataract development in the mouse , 1996, Nature Genetics.

[19]  M. Eccles,et al.  Mutation of PAX2 in two siblings with renal-coloboma syndrome. , 1995, Human molecular genetics.

[20]  S. Aso,et al.  Lens aplasia: a new mutation producing lens abnormality in the mouse. , 1995, Laboratory animal science.

[21]  M. Lyon,et al.  Close linkage of the dominant cataract mutations (Cat-2) with Idh-1 and cryge on mouse chromosome 1. , 1994, Genomics.

[22]  P. Avner,et al.  Mapping of the X-linked cataract (Xcat) mutation, the gene implicated in the Nance Horan syndrome, on the mouse X chromosome. , 1994, Genomics.

[23]  N. Copeland,et al.  Deletion map of the coloboma (Cm) locus on mouse chromosome 2. , 1994, Genomics.

[24]  M. Lyon,et al.  Mapping of six dominant cataract genes in the mouse. , 1994, Genomics.

[25]  R. Brakenhoff,et al.  Activation of the ΓE-crystallin pseudogene in the human hereditary Coppock-like cataract , 1994 .

[26]  T. Werner,et al.  Genomic sequences of murine γB- and γC-crystallm-encoding genes: promoter analysis and complete evolutionary pattern of mouse, rat and human γ-crystallins , 1993 .

[27]  D. Stambolian,et al.  Lens development in a dominant X-linked congenital cataract of the mouse. , 1993, Experimental eye research.

[28]  T. Matsuo,et al.  A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells , 1993, Nature Genetics.

[29]  Sanford H. Feldman,et al.  Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors , 1993, Nature Genetics.

[30]  L. Tsui,et al.  A frameshift mutation in the γE–crystallin gene of the Elo mouse , 1992 .

[31]  J. Favor,et al.  Allelism tests of 15 dominant cataract mutations in mice. , 1992, Genetical research.

[32]  L. Tsui,et al.  Temporal regulation of six crystallin transcripts during mouse lens development. , 1992, Experimental eye research.

[33]  R. Polizotto,et al.  Etiology of the developing eye in myelencephalic blebs (my) mice. , 1992, Histology and histopathology.

[34]  G. Saunders,et al.  Mouse Small eye results from mutations in a paired-like homeobox-containing gene , 1991, Nature.

[35]  A. Yoshiki,et al.  Developmental analysis of the eye lens obsolescence (Elo) gene in the mouse: cell proliferation and Elo gene expression in the aggregation chimera. , 1991, Development.

[36]  T. Werner,et al.  Murine γE-crystallin is distinct from murine γ2-crystallin , 1991 .

[37]  A. Matsuzawa,et al.  Biochemical evidence for conversion to milder form of hereditary mouse cataract by different genetic background. , 1991, Experimental eye research.

[38]  P. Russell,et al.  Deletion mutation in an eye lens beta-crystallin. An animal model for inherited cataracts. , 1991, The Journal of biological chemistry.

[39]  J. Favor,et al.  Genetic localization and phenotypic expression of X-linked cataract (Xcat) in Mus musculus. , 1990, Genetical research.

[40]  K. Summer,et al.  Characterization of Cat-2t, a radiation-induced dominant cataract mutation in mice. , 1990, Investigative ophthalmology & visual science.

[41]  M. Takehana Hereditary cataract of the Nakano mouse. , 1990, Experimental eye research.

[42]  T. Werner,et al.  Histological and biochemical characterization of the murine cataract mutant Nop. , 1990, Experimental eye research.

[43]  P. Reitmeir,et al.  Characterization of Scat (suture cataract), a dominant cataract mutation in mice. , 1989, Experimental eye research.

[44]  A. L. Muggleton-Harris,et al.  A gene location for the inheritance of the cataract Fraser (CatFr) mouse congenital cataract. , 1987, Genetical research.

[45]  R. van Nie,et al.  Map position of dysgenetic lens (dyl) locus on chromosome 4 in the mouse. , 1986, Genetical research.

[46]  M. Lyon,et al.  Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. , 1986, Journal of embryology and experimental morphology.

[47]  J. Zwaan,et al.  Abnormal accumulation of sulphated materials in lens tissue of mice with the aphakia mutation. , 1986, Journal of embryology and experimental morphology.

[48]  L. Tsui,et al.  Gamma-crystallin family of the mouse lens: structural and evolutionary relationships. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[49]  J. Favor Characterization of dominant cataract mutations in mice: penetrance, fertility and homozygous viability of mutations recovered after 250 mg/kg ethylnitrosourea paternal treatment. , 1984, Genetical research.

[50]  J. Zwaan,et al.  Histochemical analysis of extracellular matrix material during embryonic mouse lens morphogenesis in an aphakic strain of mice. , 1984, Developmental biology.

[51]  K. Summer,et al.  Genetical and biochemical studies of a dominant cataract mutant in mice. , 1984, Experimental eye research.

[52]  A. Silver,et al.  The extracellular matrix between the optic vesicle and presumptive lens during lens morphogenesis in an anophthalmic strain of mice. , 1984, Developmental biology.

[53]  J. Favor A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea. , 1983, Mutation research.

[54]  E. Appella,et al.  Multiple gamma-crystallins of the mouse lens: fractionation of mRNAs by cDNA cloning. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[55]  M. Lyon,et al.  Lens opacity: a new gene for congenital cataract on chromosome 10 of the mouse. , 1981, Genetical research.

[56]  J. Kratochvílová Dominant cataract mutations detected in offspring of gamma-irradiated male mice. , 1981, The Journal of heredity.

[57]  S. Fox,et al.  Head blebs: a new mutation on chromosome 4 of the mouse. , 1981, The Journal of heredity.

[58]  S. Oda,et al.  Impaired development of lens fibers in genetic microphthalmia, eye lens obsolescence, Elo, of the mouse. , 1980, Experimental eye research.

[59]  J. Kratochvílová,et al.  Dominant cataract mutations induced by gamma-irradiation of male mice. , 1979, Mutation research.

[60]  A. Coulombre Cataractogenesis: developmental inputs and constraints. , 1979, Ophthalmology.

[61]  S. Sanyal,et al.  Dysgenetic lens (dyl)--a new gene in the mouse. , 1979, Investigative ophthalmology & visual science.

[62]  H. B. Chase,et al.  Studies on an anophthalmic strain of mice. VI. Lens and cup interaction. , 1978, Developmental biology.

[63]  M. Davisson,et al.  Genes on chromosome 3 of the mouse. , 1976, Journal of Heredity.

[64]  J. Zwaan,et al.  Malorientation of mitotic figures in the early lens rudiment of aphakia mouse embryos , 1975, The Anatomical record.

[65]  J. Zwaan Immunofluorescent studies on aphakia, a mutation of a gene involved in the control of lens differentiation in the mouse embryo. , 1975, Developmental Biology.

[66]  D S Varnum,et al.  Aphakia, a new mutation in the mouse. , 1968, The Journal of heredity.

[67]  H. B. Chase Studies on an Anophthalmic Strain of Mice. IV. a Second Major Gene for Anophthalmia. , 1944, Genetics.

[68]  Ida Mann,et al.  The Development of the Human Eye , 1928, Nature.

[69]  N. Klopp,et al.  Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. , 1998, Developmental genetics.

[70]  J. Adamski,et al.  Polymorphism in the murine Tr2-11 gene encoding an orphan receptor, and its exclusion as a candidate gene for the cataract mutation Cat3. , 1998, Biological chemistry.

[71]  V. van Heyningen,et al.  PAX6 mutations reviewed , 1998, Human mutation.

[72]  H. Hiai,et al.  Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse. , 1997, Experimental eye research.

[73]  V. Klauss,et al.  Epidemiology of blindness and eye disease. , 1996, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde.

[74]  R. Odicasandulache The mouse Pax2 1Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney , 1996 .

[75]  J. Favor Mutagenesis and human genetic disease: Dominant mutation frequencies and a characterization of mutational events in mice and humans , 1995, Environmental and molecular mutagenesis.

[76]  U. Ehling Genetic risk assessment. , 1991, Annual review of genetics.

[77]  T. Werner,et al.  Murine gamma E-crystallin is distinct from murine gamma 2-crystallin. , 1991, Gene.

[78]  J. Favor,et al.  Dominant cataract and recessive specific locus mutations in offspring of X-irradiated male mice. , 1986, Mutation research.

[79]  J. Zwaan,et al.  Localization of keratin in the cells of the cornea in aphakia and normal mouse embryos. , 1985, Experimental eye research.

[80]  J. Favor,et al.  Induction of gene mutations in mice: the multiple endpoint approach. , 1985, Mutation research.

[81]  Koniukhov Bv,et al.  Action of mutant genes on crystallin synthesis in the developing mouse lens. III. The aphakia gene , 1981 .