Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein

[1]  Y. Samstag,et al.  Oxidation of cofilin mediates T cell hyporesponsiveness under oxidative stress conditions. , 2008, Immunity.

[2]  A. Aguzzi,et al.  The prion's elusive reason for being. , 2008, Annual review of neuroscience.

[3]  H. Hartung,et al.  Prion proteins: Physiological functions and role in neurological disorders , 2008, Journal of the Neurological Sciences.

[4]  G. Jackson,et al.  The role of the cellular prion protein in the immune system , 2006, Clinical and experimental immunology.

[5]  C. Hivroz,et al.  Functional Implication of Cellular Prion Protein in Antigen-Driven Interactions between T Cells and Dendritic Cells1 , 2006, The Journal of Immunology.

[6]  J. Laurent,et al.  Early thymic T cell development in young transgenic mice overexpressing human Cu/Zn superoxide dismutase, a model of Down syndrome. , 2006, Free radical biology & medicine.

[7]  A. Favier,et al.  Overexpression of Cellular Prion Protein Induces an Antioxidant Environment Altering T Cell Development in the Thymus1 , 2006, The Journal of Immunology.

[8]  H. Plattner,et al.  PrPc capping in T cells promotes its association with the lipid raft proteins reggie‐1 and reggie‐2 and leads to signal transduction , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[9]  C. Zurzolo,et al.  PrP(C) association with lipid rafts in the early secretory pathway stabilizes its cellular conformation. , 2004, Molecular biology of the cell.

[10]  Dae-Yeul Yu,et al.  Reactive oxygen species induced by the deletion of peroxiredoxin II (PrxII) increases the number of thymocytes resulting in the enlargement of PrxII‐null thymus , 2004, European journal of immunology.

[11]  C. Romanin,et al.  Co‐localization of CD3 and prion protein in Jurkat lymphocytes after hypothermal stimulation , 2004, FEBS letters.

[12]  V. Manganelli,et al.  Prion protein is a component of the multimolecular signaling complex involved in T cell activation , 2004, FEBS letters.

[13]  V. Mutel,et al.  NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[14]  David A Padgett,et al.  How stress influences the immune response. , 2003, Trends in immunology.

[15]  L. Herzenberg,et al.  Lymphocyte surface thiol levels , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[16]  R. Ceredig,et al.  A positive look at double-negative thymocytes , 2002, Nature Reviews Immunology.

[17]  W. Savino The thymus gland is a target in malnutrition , 2002, European Journal of Clinical Nutrition.

[18]  S. Lehmann,et al.  Oxidative stress and the prion protein in transmissible spongiform encephalopathies , 2002, Brain Research Reviews.

[19]  G. Filomeni,et al.  Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[20]  G. Edelman,et al.  Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. , 2001, Journal of molecular biology.

[21]  H. Schätzl,et al.  PrPC Directly Interacts with Proteins Involved in Signaling Pathways* , 2001, The Journal of Biological Chemistry.

[22]  D. Dormont,et al.  Identification of interaction domains of the prion protein with its 37‐kDa/67‐kDa laminin receptor , 2001, The EMBO journal.

[23]  M. Briehl,et al.  Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis , 2001, Cell Death and Differentiation.

[24]  J. Hescheler,et al.  Reactive Oxygen Species as Intracellular Messengers During Cell Growth and Differentiation , 2001, Cellular Physiology and Biochemistry.

[25]  S. Itohara,et al.  Distribution of cellular isoform of prion protein in T lymphocytes and bone marrow, analyzed by wild-type and prion protein gene-deficient mice. , 2001, Biochemical and biophysical research communications.

[26]  M. Sy,et al.  Normal Cellular Prior Protein Is Preferentially Expressed on Subpopulations of Murine Hemopoietic Cells , 2001, The Journal of Immunology.

[27]  S. Haswell,et al.  Antioxidant activity related to copper binding of native prion protein , 2001, Journal of neurochemistry.

[28]  D. F. Barber,et al.  NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development. , 2000, Immunity.

[29]  J. Laplanche,et al.  Signal transduction through prion protein. , 2000, Science.

[30]  M. Sy,et al.  Differential contribution of superoxide dismutase activity by prion protein in vivo. , 2000, Biochemical and biophysical research communications.

[31]  C. Epstein,et al.  Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis , 2000, Critical care medicine.

[32]  F. Breedveld,et al.  Displacement of Linker for Activation of T Cells from the Plasma Membrane Due to Redox Balance Alterations Results in Hyporesponsiveness of Synovial Fluid T Lymphocytes in Rheumatoid Arthritis , 2000, The Journal of Immunology.

[33]  S. Haswell,et al.  Normal prion protein has an activity like that of superoxide dismutase. , 1999, The Biochemical journal.

[34]  K. Beyreuther,et al.  Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity. , 1999, The American journal of pathology.

[35]  E. Rock,et al.  Accelerated thymus involution in magnesium-deficient rats is related to enhanced apoptosis and sensitivity to oxidative stress , 1999, British Journal of Nutrition.

[36]  B. Faucheux,et al.  Cellular prion protein localization in rodent and primate brain , 1998, The European journal of neuroscience.

[37]  F. Cohen,et al.  Prion protein selectively binds copper(II) ions. , 1998, Biochemistry.

[38]  M. Hurme,et al.  Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes. , 1998, Journal of immunology.

[39]  D. Westaway,et al.  The cellular prion protein binds copper in vivo , 1997, Nature.

[40]  C. Shaw,et al.  Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death , 1997, Brain Research Reviews.

[41]  K. Muegge,et al.  p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation. , 1997, Biochimie.

[42]  T. Noda,et al.  Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene , 1996, Nature.

[43]  Bernhard Schmidt,et al.  Role of microglia and host prion protein in neurotoxicity of a prion protein fragment , 1996, Nature.

[44]  N. Ishiguro,et al.  A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep. , 1995, The Journal of general virology.

[45]  J. Lotem,et al.  Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn‐superoxide dismutase: implications for Down syndrome. , 1995, The EMBO journal.

[46]  J. Lakey,et al.  Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. , 1995, Biochemical and biophysical research communications.

[47]  M. Palmer,et al.  Prion protein is necessary for normal synaptic function , 1994, Nature.

[48]  D. Hedley,et al.  Evaluation of methods for measuring cellular glutathione content using flow cytometry. , 1994, Cytometry.

[49]  V. Ivanov,et al.  Antioxidant treatment of thymic organ cultures decreases NF-kappa B and TCF1(alpha) transcription factor activities and inhibits alpha beta T cell development. , 1993, Journal of immunology.

[50]  Scott W. Lowe,et al.  p53 is required for radiation-induced apoptosis in mouse thymocytes , 1993, Nature.

[51]  C. Purdie,et al.  Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.

[52]  X. M. Sun,et al.  Characterization of apoptosis in thymocytes isolated from dexamethasone-treated rats. , 1992, Biochemical pharmacology.

[53]  S. Prusiner,et al.  Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein , 1992, Nature.

[54]  R. Lechler,et al.  Stress-induced modulation of antigen-presenting cell function. , 1991, Immunology.

[55]  S. Prusiner,et al.  Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. , 1990, Biochemistry.

[56]  D. Shrieve,et al.  Heterogeneity of cellular glutathione among cells derived from a murine fibrosarcoma or a human renal cell carcinoma detected by flow cytometric analysis. , 1988, The Journal of biological chemistry.

[57]  I. Clark,et al.  Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin. , 1988, Cellular immunology.

[58]  J. Zúñiga-Pflücker T-cell development made simple , 2004, Nature Reviews Immunology.

[59]  A. Favier,et al.  Oxidative stress impairs intracellular events involved in antigen processing and presentation to T cells , 2003, Cell stress & chaperones.

[60]  J. Fournier,et al.  Nonneuronal cellular prion protein. , 2001, International review of cytology.

[61]  M. Bachmann,et al.  Selection of the T cell repertoire. , 1999, Annual review of immunology.

[62]  M. Martínez-Cayuela Oxygen free radicals and human disease. , 1995, Biochimie.

[63]  S. Prusiner,et al.  Scrapie prion proteins are synthesized in neurons. , 1986, The American journal of pathology.

[64]  I. Carlberg,et al.  Glutathione reductase. , 1985, Methods in enzymology.

[65]  B. Mannervik,et al.  [59] Glutathione reductase , 1985 .