The primary stability of a cementless stem varies between subjects as much as between activities.

The rehabilitation program adopted immediately after a cementless total hip replacement is a very important factor, because of the known relationship between osseointegration and implant micromotion. The present study was aimed to evaluate which type of task is the most critical in terms of bone-implant relative micromotion. Both inter-task and inter-subject variability were taken into account to verify if the movement strategy could be determinant on this assessment. A previously validated finite element model was used to predict the peak total micromovements over the entire bone-implant contact surface in four different patients, performing nine different tasks, using published data on joint forces recorded by instrumented hip prostheses. The results predicted by the various simulations suggest that while stair climbing is surely a critical task for primary stability, for some subjects other tasks may be as critical as stair climbing. From a variance analysis for simple crossover design on the predicted peak micromotion, the inter-subject variability had much more influence on the primary stability of cementless implant than the inter-task variability. Even if the results of Patient IBL, who was reported to have difficulties to perform any activities in a normal way, were excluded from the statistical analysis, the inter-subject variability remained still higher than the inter-task variability. The results obtained from simulations suggest that the strategy the hip replacement patient adopts to perform a given motor task, may be, for the implant stability, equally or even more critical than the type of motor task performed.

[1]  F. Zappoli,et al.  The use of ceramic in prosthetic hip surgery. The state of the art. , 1995, La Chirurgia degli organi di movimento.

[2]  I C Clarke,et al.  Mechanism and clinical significance of wear debris-induced osteolysis. , 1992, Clinical orthopaedics and related research.

[3]  A. Meunier,et al.  The elastic anisotropy of bone. , 1987, Journal of biomechanics.

[4]  A Rohlmann,et al.  Finite-element-analysis and experimental investigation in a femur with hip endoprosthesis. , 1983, Journal of biomechanics.

[5]  T. Brown,et al.  Mechanical property distributions in the cancellous bone of the human proximal femur. , 1980, Acta orthopaedica Scandinavica.

[6]  Wroblewski Bm,et al.  Charnley low-friction arthroplasty of the hip. Long-term results. , 1993 .

[7]  P Herberts,et al.  Prognosis of total hip replacement: A Swedish multicenter study of 4,664 revisions , 1990 .

[8]  W. Harris,et al.  The problem is osteolysis. , 1995, Clinical orthopaedics and related research.

[9]  G. Bergmann,et al.  Hip joint loading during walking and running, measured in two patients. , 1993, Journal of biomechanics.

[10]  Bernard F. Morrey,et al.  Biological, Material, and Mechanical Considerations of Joint Replacement , 1993 .

[11]  G W Blunn,et al.  A comparison of bone remodelling around hydroxyapatite-coated, porous-coated and grit-blasted hip replacements retrieved at post-mortem. , 2001, The Journal of bone and joint surgery. British volume.

[12]  Bristol-Myers Squibb,et al.  Total Hip Revision Surgery , 1995 .

[13]  R E Booth,et al.  Comparison of interface membranes obtained from failed cemented and cementless hip and knee prostheses. , 1994, Clinical orthopaedics and related research.

[14]  A Perrenoud,et al.  [Physical therapy aspects of treatment following total hip prosthesis]. , 1991, Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis.

[15]  W. Hayes,et al.  Mechanical properties of trabecular bone from the proximal femur: a quantitative CT study. , 1990, Journal of computer assisted tomography.

[16]  H. Amstutz,et al.  "Modes of failure" of cemented stem-type femoral components: a radiographic analysis of loosening. , 1979, Clinical orthopaedics and related research.

[17]  G. Bergmann,et al.  Hip contact forces and gait patterns from routine activities. , 2001, Journal of biomechanics.

[18]  Dieter Christian Wirtz,et al.  Biomechanische Aspekte der Belastungsfähigkeit nach totalendoprothetischem Ersatz des Hüftgelenkes , 2008 .

[19]  T Q Lee,et al.  Initial stability comparison of modular hip implants in synthetic femurs. , 1998, Orthopedics.

[20]  Nicholas G. Sotereanos,et al.  Cementless Femoral Components Should Be Made From Cobalt Chrome , 1995, Clinical orthopaedics and related research.

[21]  L Ryd,et al.  Micromotion of a noncemented tibial component with screw fixation. An in vivo roentgen stereophotogrammetric study of the Miller-Galante prosthesis. , 1993, Clinical orthopaedics and related research.

[22]  Marco Viceconti,et al.  The role of parameter identification in finite element contact analyses with reference to orthopaedic biomechanics applications. , 2002, Journal of biomechanics.

[23]  M. B. Coventry,et al.  Charnley low-friction arthroplasty of the hip. Twenty-year results with cement. , 1994, The Journal of arthroplasty.

[24]  R Van Audekercke,et al.  The mechanical characteristics of cancellous bone at the upper femoral region. , 1983, Journal of biomechanics.

[25]  K. Radermacher,et al.  Critical evaluation of known bone material properties to realize anisotropic FE-simulation of the proximal femur. , 2000, Journal of biomechanics.

[26]  W C Hayes,et al.  Mechanical properties of metaphyseal bone in the proximal femur. , 1991, Journal of biomechanics.

[27]  A. Burstein,et al.  The elastic and ultimate properties of compact bone tissue. , 1975, Journal of biomechanics.

[28]  Reinhard Windhager,et al.  Proximal femoral bone loss and increased rate of fracture with a proximally hydroxyapatite-coated femoral component , 2000 .

[29]  W J Maloney,et al.  The initiation of failure in cemented femoral components of hip arthroplasties. , 1991, The Journal of bone and joint surgery. British volume.

[30]  C. Bünger,et al.  Hydroxyapatite coating modifies implant membrane formation. Controlled micromotion studied in dogs. , 1992, Acta orthopaedica Scandinavica.

[31]  M. A. R. Freeman,et al.  The production and biology of polyethylene wear debris , 1978, Archives of orthopaedic and traumatic surgery.

[32]  P. Massin,et al.  Cementless fixation of hip prostheses in dogs , 2004, International Orthopaedics.

[33]  G. Bergmann,et al.  Interfacial conditions between a press-fit acetabular cup and bone during daily activities: implications for achieving bone in-growth. , 2000, Journal of Biomechanics.

[34]  W H Harris,et al.  Quantification of Implant Micromotion, Strain Shielding, and Bone Resorption With Porous‐Coated Anatomic Medullary Locking Femoral Prostheses , 1992, Clinical orthopaedics and related research.

[35]  L Cristofolini,et al.  Large-sliding contact elements accurately predict levels of bone-implant micromotion relevant to osseointegration. , 2000, Journal of biomechanics.

[36]  J. BotellaLlusiá,et al.  [Long-term results]. , 1983, Anales de la Real Academia Nacional de Medicina.

[37]  A. Burstein,et al.  The elastic modulus for bone. , 1974, Journal of biomechanics.

[38]  Aivars Berzins,et al.  Accuracy and precision of radiostereometric analysis in the measurement of THR femoral component translations: human and canine in vitro models , 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[39]  H. Amstutz,et al.  The pathology of failed total joint arthroplasty. , 1982, Clinical orthopaedics and related research.

[40]  T W Bilotta,et al.  Rehabilitation treatment in cemented and cementless prostheses. , 1992, La Chirurgia degli organi di movimento.

[41]  J. M. Lee,et al.  Observations on the Effect of Movement on Bone Ingrowth into Porous‐Surfaced Implants , 1986, Clinical orthopaedics and related research.

[42]  C. Bünger,et al.  Hydroxyapatite coating converts fibrous tissue to bone around loaded implants. , 1993, The Journal of bone and joint surgery. British volume.