Novel synthesis of steryl esteryl esters from β-sitosterol and N-phosphoryl amino acid under microwave irradiation

GRAPHICAL ABSTRACT ABSTRACT Ten novel N-phosphoryl amino acids β-sitosterol esters were synthesized by coupling the N-phosphoryl amino acids with β-sitosterol under microwave irradiation, and their structures were elucidated by IR, NMR, and HR MS. Various reaction conditions including the catalyst, solvent, temperature and time were investigated. Under the optimal conditions, the reaction was finished in 20 min with 60–87% yields by employing DCC/DMAP as a catalyst system at room temperature.

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