A simple and high production rate manufacturing method for submicron polymer fibres

The manufacturing technique for cotton‐candy floss, heat‐aided rotary jet‐spinning, was used to produce submicron‐scale fibrous meshes by using bioabsorbable thermoplastic polymers. The method was feasible for 100 wt% polymer concentrations functioning completely without solvents. It was possible to produce submicron diameter fibres using a simple device, which indicates that this manufacturing method is a very promising technique for obtaining high‐throughput rates for submicron, and possibly nano‐scale, fibrous meshes. Copyright © 2011 John Wiley & Sons, Ltd.

[1]  D. C. Knapp,et al.  Electrospun polydioxanone–elastin blends: potential for bioresorbable vascular grafts , 2006, Biomedical materials.

[2]  Kevin Kit Parker,et al.  Nanofiber assembly by rotary jet-spinning. , 2010, Nano letters.

[3]  M. Kellomäki,et al.  Processing of Resorbable Poly-α-Hydroxy Acids for Use as Tissue-Engineering Scaffolds , 2004 .

[4]  P. Westbroek,et al.  Electrospinning of chitosan nanofibrous structures: feasibility study , 2007 .

[5]  P. Törmälä,et al.  Biodegradable self-reinforced composite materials; manufacturing structure and mechanical properties. , 1992, Clinical materials.

[6]  P. Törmälä,et al.  Bioabsorbable polymers: Materials technology and surgical applications , 1998, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[7]  M. Kellomäki,et al.  Pliable polylactide plates for guided bone regeneration: Manufacturing and in vitro , 2000, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[8]  S. Ramakrishna,et al.  A review on electrospinning design and nanofibre assemblies , 2006, Nanotechnology.

[9]  M. Kellomäki,et al.  Fibre reinforced bioresorbable composites for spinal surgery. , 2006, Acta biomaterialia.

[10]  P. Törmälä,et al.  Surgical applications of biodegradable polymers in human tissues , 1989 .

[11]  Xiumei Mo,et al.  Electrospinning of collagen–chitosan complex , 2007 .

[12]  M. Kellomäki,et al.  Fiber-reinforced bioactive and bioabsorbable hybrid composites , 2008, Biomedical materials.

[13]  C. Bashur,et al.  Effect of fiber diameter and orientation on fibroblast morphology and proliferation on electrospun poly(D,L-lactic-co-glycolic acid) meshes. , 2006, Biomaterials.

[14]  V. Ellä,et al.  Melt spinning of poly(l/d)lactide 96/4: Effects of molecular weight and melt processing on hydrolytic degradation , 2009 .

[15]  V. Ellä,et al.  Process‐induced monomer on a medical‐grade polymer and its effect on short‐term hydrolytic degradation , 2011 .

[16]  H. Kim,et al.  Electrospinning biomedical nanocomposite fibers of hydroxyapatite/poly(lactic acid) for bone regeneration. , 2006, Journal of biomedical materials research. Part A.