rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype
暂无分享,去创建一个
C. Polychronakos | G. Morahan | N. Bottini | B. Boehm | P. Concannon | C. Julier | A. Steck | G. Eisenbarth | J. Noble | J. She | Erin E. Baschal | E. Baschal | J. Jasinski | J. Jasinski | Janelle A. Noble | Cécile Julier | Grant Morahan | Andrea K. Steck | Bernhard O. Boehm | Nunzio Bottini | Patrick Concannon | Constantin Polychronakos | G. Eisenbarth
[1] K. Lohman,et al. Overview of the Rapid Response data , 2009, Genes and Immunity.
[2] J. Ilonen,et al. Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant. , 2008, Journal of autoimmunity.
[3] D. Clayton,et al. PTPN22 Trp620 Explains the Association of Chromosome 1p13 With Type 1 Diabetes and Shows a Statistical Interaction With HLA Class II Genotypes , 2008, Diabetes.
[4] N. Bottini,et al. Further Evidence of a Primary, Causal Association of the PTPN22 620W Variant With Type 1 Diabetes , 2008, Diabetes.
[5] P. Concannon,et al. Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes1 , 2007, The Journal of Immunology.
[6] Simon C. Potter,et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.
[7] F. Pociot,et al. PTPN22 R620W Functional Variant in Type 1 Diabetes and Autoimmunity Related Traits , 2007, Diabetes.
[8] M. Rewers,et al. Association of the PTPN22/LYP gene with type 1 diabetes , 2006, Pediatric diabetes.
[9] P. Concannon,et al. A Haplotype-Based Analysis of the PTPN22 Locus in Type 1 Diabetes , 2006, Diabetes.
[10] J. Ilonen,et al. Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes , 2006, Diabetologia.
[11] K. Eguchi,et al. Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): Association between a promoter polymorphism and type 1 diabetes in Asian populations , 2006 .
[12] Nunzio Bottini,et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant , 2005, Nature Genetics.
[13] Annette Lee,et al. Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (madgc) Collection: the Ptpn22 620w Allele Associates with Multiple Autoimmune Phenotypes , 2022 .
[14] J. She,et al. Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes. , 2005, Diabetes.
[15] T. Hudson,et al. Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study , 2005, Journal of Medical Genetics.
[16] Mark Daly,et al. Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..
[17] R. Quinton,et al. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. , 2004, The Journal of clinical endocrinology and metabolism.
[18] Adrian Vella,et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. , 2004, Diabetes.
[19] Kristin G Ardlie,et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. , 2004, American journal of human genetics.
[20] Steven J. Schrodi,et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. , 2004, American journal of human genetics.
[21] Nunzio Bottini,et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes , 2004, Nature Genetics.
[22] J. Visvader,et al. Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region , 2003, Cell Death and Differentiation.
[23] J. Cloutier,et al. Cooperative Inhibition of T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase , 1999, The Journal of experimental medicine.
[24] G. Thomson. Mapping disease genes: family-based association studies. , 1995, American journal of human genetics.
[25] K. Mossman. The Wellcome Trust Case Control Consortium, U.K. , 2008 .
[26] J. She,et al. Genetic Association Between a Lymphoid Tyrosine Phosphatase ( PTPN 22 ) and Type 1 Diabetes , 2005 .
[27] N. Bottini,et al. Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes. , 2005, Human immunology.
[28] G. Abecasis,et al. Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.