The mechanism of 3' cleavage and polyadenylation of eukaryotic pre-mRNA.

[1]  W. Keller,et al.  Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases. , 1996, The EMBO journal.

[2]  W. Keller,et al.  Purification and Characterization of Human Cleavage Factor I Involved in the 3′ End Processing of Messenger RNA Precursors (*) , 1996, The Journal of Biological Chemistry.

[3]  K. Murthy,et al.  Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. , 1996, Genes & development.

[4]  O. Resnekov,et al.  Repression of beta interferon gene expression in virus-infected cells is correlated with a poly(A) tail elongation , 1996, Molecular and cellular biology.

[5]  J. Gergen,et al.  Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development. , 1996, Development.

[6]  H. Lou,et al.  An intron enhancer recognized by splicing factors activates polyadenylation. , 1996, Genes & development.

[7]  P. Silver,et al.  Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. , 1996, Genetics.

[8]  J. Richter,et al.  Cytoplasmic 3′ poly(A) addition induces 5′ cap ribose methylation: implications for translational control of maternal mRNA. , 1995, The EMBO journal.

[9]  N. Proudfoot,et al.  Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site. , 1995, Genes & development.

[10]  R. Parker,et al.  Effects of mutations in the Saccharomyces cerevisiae RNA14, RNA15, and PAP1 genes on polyadenylation in vivo , 1995, Molecular and cellular biology.

[11]  A. Sachs,et al.  A common function for mRNA 5' and 3' ends in translation initiation in yeast. , 1995, Genes & development.

[12]  Marco M. Kessler,et al.  Structure-Function Relationships in the Saccharomyces cerevisiae Poly(A) Polymerase , 1995, The Journal of Biological Chemistry.

[13]  K. Murthy,et al.  The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. , 1995, Genes & development.

[14]  F. Sherman,et al.  3'-end-forming signals of yeast mRNA , 1995, Molecular and cellular biology.

[15]  G. Hayward,et al.  Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA , 1995, Journal of virology.

[16]  Chris Sander,et al.  DNA polymerase β belongs to an ancient nucleotidyltransferase superfamily , 1995 .

[17]  J. Brown,et al.  Molecular characterization of the spliceosomal proteins U1A and U2B″ from higher plants. , 1995, The EMBO journal.

[18]  G. Carmichael,et al.  Characterization of the polyomavirus late polyadenylation signal , 1995, Molecular and cellular biology.

[19]  F. Lacroute,et al.  The duplicated Saccharomyces cerevisiae gene SSM1 encodes a eucaryotic homolog of the eubacterial and archaebacterial L1 ribosomal proteins , 1995, Molecular and cellular biology.

[20]  M. Wollerton,et al.  Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved. , 1995, The EMBO journal.

[21]  W. Keller,et al.  Cloning of cDNAs encoding the 160 kDa subunit of the bovine cleavage and polyadenylation specificity factor. , 1995, Nucleic acids research.

[22]  W. Keller,et al.  No end yet to messenger RNA 3′ processing! , 1995, Cell.

[23]  F. Gebauer,et al.  Cloning and characterization of a Xenopus poly(A) polymerase , 1995, Molecular and cellular biology.

[24]  J. Wilusz,et al.  The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor. , 1995, Nucleic acids research.

[25]  J. Butler,et al.  Redundant 3' end-forming signals for the yeast CYC1 mRNA. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[26]  A. Sittler,et al.  The secondary structure of the adenovirus-2 L4 polyadenylation domain: evidence for a hairpin structure exposing the AAUAAA signal in its loop. , 1995, Journal of molecular biology.

[27]  L. Minvielle-Sebastia,et al.  The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase , 1995, Cell.

[28]  C. Springer,et al.  A complex unidirectional signal element mediates GCN4 mRNA 3' end formation in Saccharomyces cerevisiae , 1995, Molecular and cellular biology.

[29]  Roy Parker,et al.  Degradation of mRNA in eukaryotes , 1995, Cell.

[30]  K. Hall,et al.  An RBD that does not bind RNA: NMR secondary structure determination and biochemical properties of the C-terminal RNA binding domain from the human U1A protein. , 1995, Journal of molecular biology.

[31]  E. Wahle,et al.  3'-end cleavage and polyadenylation of mRNA precursors. , 1995, Biochimica et biophysica acta.

[32]  J. Nevins,et al.  Identification of an activity in B-cell extracts that selectively impairs the formation of an immunoglobulin mu s poly(A) site processing complex , 1995, Molecular and cellular biology.

[33]  J. Manley,et al.  A complex protein assembly catalyzes polyadenylation of mRNA precursors. , 1995, Current opinion in genetics & development.

[34]  M. Wickens,et al.  Poly (A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development. , 1995, RNA.

[35]  T. Platt,et al.  REF2 encodes an RNA-binding protein directly involved in yeast mRNA 3'-end formation , 1995, Molecular and cellular biology.

[36]  E. Wahle,et al.  Poly(A) Tail Length Control Is Caused by Termination of Processive Synthesis (*) , 1995, The Journal of Biological Chemistry.

[37]  C. Moore,et al.  Monoclonal antibodies to yeast poly(A) polymerase (PAP) provide evidence for association of PAP with cleavage factor I. , 1995, Biochemistry.

[38]  H. Bourbon,et al.  Novel Drosophila melanogaster genes encoding RRM-type RNA-binding proteins identified by a degenerate PCR strategy. , 1995, Gene.

[39]  B. Graveley,et al.  CPSF recognition of an HIV-1 mRNA 3'-processing enhancer: multiple sequence contacts involved in poly(A) site definition. , 1995, Genes & development.

[40]  J. Gergen,et al.  Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. , 1994, Science.

[41]  L. Minvielle-Sebastia,et al.  RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor. , 1994, Science.

[42]  H. Hauri,et al.  Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit , 1994, Molecular and cellular biology.

[43]  M. Peterson.  Regulated immunoglobulin (Ig) RNA processing does not require specific cis-acting sequences: non-Ig RNA can be alternatively processed in B cells and plasma cells , 1994, Molecular and cellular biology.

[44]  J. Manley,et al.  A polyadenylation factor subunit is the human homologue of theDrosophila suppressor of forked protein , 1994, Nature.

[45]  J. Richter,et al.  Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element-binding proteins , 1994, Molecular and cellular biology.

[46]  J. Richter,et al.  CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation , 1994, Cell.

[47]  G. Braus,et al.  Uncoupling of mRNA 3' cleavage and polyadenylation by expression of a hammerhead ribozyme in yeast. , 1994, The Journal of biological chemistry.

[48]  P Sarnow,et al.  Cap-dependent and cap-independent translation by internal initiation of mRNAs in cell extracts prepared from Saccharomyces cerevisiae , 1994, Molecular and cellular biology.

[49]  T. Shenk,et al.  The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location , 1994, Molecular and cellular biology.

[50]  J. Richter,et al.  Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development , 1994, Molecular and cellular biology.

[51]  E. Wahle,et al.  Immunodetection of poly(A) binding protein II in the cell nucleus. , 1994, Experimental cell research.

[52]  M. A. Hardwicke,et al.  The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection , 1994, Journal of virology.

[53]  C. Baker,et al.  Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions , 1994, Molecular and cellular biology.

[54]  C. Burd,et al.  Conserved structures and diversity of functions of RNA-binding proteins. , 1994, Science.

[55]  Fan Chen,et al.  Sequence and position requirements for uridylate-rich downstream elements of polyadenylation signals , 1994, Nucleic Acids Res..

[56]  H. Domdey,et al.  Flexibility and interchangeability of polyadenylation signals in Saccharomyces cerevisiae , 1994, Molecular and cellular biology.

[57]  E. Falck-Pedersen,et al.  Sequence elements upstream of the 3' cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites , 1994, Molecular and cellular biology.

[58]  Samuel H. Wilson,et al.  Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. , 1994, Science.

[59]  K. Murthy,et al.  Poly(A) polymerase contains multiple functional domains , 1994, Molecular and cellular biology.

[60]  M. Wickens,et al.  The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. , 1994, Genes & development.

[61]  L. Minvielle-Sebastia,et al.  Cellular localization of RNA14p and RNA15p, two yeast proteins involved in mRNA stability. , 1994, Journal of cell science.

[62]  J. Alwine,et al.  Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal. , 1994, Genes & development.

[63]  W. Boelens,et al.  The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase , 1994, Cell.

[64]  A. Virtanen,et al.  Multiple forms of poly(A) polymerases in human cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[65]  G. Braus,et al.  Saturation mutagenesis of a polyadenylation signal reveals a hexanucleotide element essential for mRNA 3' end formation in Saccharomyces cerevisiae. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[66]  M. Peiter,et al.  Exon size affects competition between splicing and cleavage-polyadenylation in the immunoglobulin mu gene , 1994, Molecular and cellular biology.

[67]  F. Sherman,et al.  Signals that produce 3' termini in CYC1 mRNA of the yeast Saccharomyces cerevisiae , 1993, Molecular and cellular biology.

[68]  W. Boelens,et al.  A complex secondary structure in U1A pre‐mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation. , 1993, The EMBO journal.

[69]  A. Myers,et al.  Functional analysis of mRNA 3' end formation signals in the convergent and overlapping transcription units of the S. cerevisiae genes RHO1 and MRP2. , 1993, Nucleic acids research.

[70]  C. Moore,et al.  Termination and pausing of RNA polymerase II downstream of yeast polyadenylation sites , 1993, Molecular and cellular biology.

[71]  J. Nevins,et al.  Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor , 1993, Molecular and cellular biology.

[72]  W. Boelens,et al.  The human U1 snRNP-Specific U1A protein inhibits polyadenylation of its own pre-mRNA , 1993, Cell.

[73]  A. Lustig,et al.  Mammalian poly(A)-binding protein II. Physical properties and binding to polynucleotides. , 1993, The Journal of biological chemistry.

[74]  E. Wahle,et al.  Assembly of a processive messenger RNA polyadenylation complex. , 1993, The EMBO journal.

[75]  M. Wickens,et al.  Polyadenylation of maternal mRNA during oocyte maturation: poly(A) addition in vitro requires a regulated RNA binding activity and a poly(A) polymerase. , 1992, The EMBO journal.

[76]  J. Richter,et al.  Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element. , 1992, Genes & development.

[77]  A. Phelan,et al.  Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing , 1992, Journal of virology.

[78]  E. Fleming,et al.  Activation of HIV‐1 pre‐mRNA 3′ processing in vitro requires both an upstream element and TAR. , 1992, The EMBO journal.

[79]  M. Imperiale,et al.  Relative roles of signals upstream of AAUAAA and promoter proximity in regulation of human immunodeficiency virus type 1 mRNA 3' end formation , 1992, Molecular and cellular biology.

[80]  M. Wickens,et al.  Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure. , 1992, Genes & development.

[81]  T. Platt,et al.  Unusual aspects of in vitro RNA processing in the 3' regions of the GAL1, GAL7, and GAL10 genes in Saccharomyces cerevisiae , 1992, Molecular and cellular biology.

[82]  J. Alwine,et al.  Elements upstream of the AAUAAA within the human immunodeficiency virus polyadenylation signal are required for efficient polyadenylation in vitro , 1992, Molecular and cellular biology.

[83]  B. Obermaier,et al.  Identification of pre-mRNA polyadenylation sites in Saccharomyces cerevisiae , 1992, Molecular and cellular biology.

[84]  V. Kruys,et al.  Alternative polyadenylation of the amyloid protein precursor mRNA regulates translation. , 1992, EMBO Journal.

[85]  R. Pastori,et al.  Differential regulation and polyadenylation of transferrin mRNA in Xenopus liver and oviduct , 1992, The Journal of Steroid Biochemistry and Molecular Biology.

[86]  K. Murthy,et al.  Characterization of the multisubunit cleavage-polyadenylation specificity factor from calf thymus. , 1992, The Journal of biological chemistry.

[87]  J. Butler,et al.  Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase , 1992, Molecular and cellular biology.

[88]  F. Sallés,et al.  Isolation of novel murine maternal mRNAs regulated by cytoplasmic polyadenylation. , 1992, Genes & development.

[89]  G. Morgan,et al.  Alternative 3' processing of Xenopus alpha-tubulin mRNAs; efficient use of a CAUAAA polyadenylation signal. , 1992, Nucleic acids research.

[90]  D. Belin,et al.  Transient translational silencing by reversible mRNA deadenylation , 1992, Cell.

[91]  D. Carter,et al.  Posttranscriptional regulation of rat growth hormone gene expression: increased message stability and nuclear polyadenylation accompany thyroid hormone depletion , 1992, Molecular and cellular biology.

[92]  G. Braus,et al.  Different sequence elements are required for function of the cauliflower mosaic virus polyadenylation site in Saccharomyces cerevisiae compared with in plants , 1992, Molecular and cellular biology.

[93]  R. Sandri-Goldin,et al.  A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing. , 1992, Genes & development.

[94]  E. Falck-Pedersen,et al.  Varied poly(A) site efficiency in the adenovirus major late transcription unit. , 1992, The Journal of biological chemistry.

[95]  J. Cherrington,et al.  Regulation of polyadenylation in human immunodeficiency virus (HIV): contributions of promoter proximity and upstream sequences. , 1992, The EMBO journal.

[96]  G. Luo,et al.  Genetic analysis of influenza virus , 1992, Current Biology.

[97]  J. Manley,et al.  The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[98]  E. Wahle.  The end of the message: 3'– end processing leading to polyadenylated messenger RNA , 1992, BioEssays : news and reviews in molecular, cellular and developmental biology.

[99]  E. Wahle,et al.  The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors. , 1992, Annual review of biochemistry.

[100]  J. Lingner,et al.  Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae , 1991, Nature.

[101]  R. Russnak.  Regulation of polyadenylation in hepatitis B viruses: stimulation by the upstream activating signal PS1 is orientation-dependent, distance-independent, and additive. , 1991, Nucleic acids research.

[102]  J. Taylor,et al.  Regulation of polyadenylation of hepatitis delta virus antigenomic RNA , 1991, Journal of virology.

[103]  M. Imperiale,et al.  Sequences regulating temporal poly(A) site switching in the adenovirus major late transcription unit , 1991, Molecular and cellular biology.

[104]  E. Wahle,et al.  Isolation and expression of cDNA clones encoding mammalian poly(A) polymerase. , 1991, The EMBO journal.

[105]  G. Christofori,et al.  Cleavage and polyadenylation factor CPF specifically interacts with the pre‐mRNA 3′ processing signal AAUAAA. , 1991, The EMBO journal.

[106]  T. Platt,et al.  Homologous mRNA 3′ end formation in fission and budding yeast. , 1991, The EMBO journal.

[107]  D. Gallie.  The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. , 1991, Genes & development.

[108]  E. Wahle,et al.  Purification of the cleavage and polyadenylation factor involved in the 3'-processing of messenger RNA precursors. , 1991, The Journal of biological chemistry.

[109]  J. Wilusz,et al.  An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal , 1991, Molecular and cellular biology.

[110]  G. Carmichael,et al.  Splice site choice in a complex transcription unit containing multiple inefficient polyadenylation signals , 1991, Molecular and cellular biology.

[111]  A. Bar‐Shira,et al.  An RNA secondary structure juxtaposes two remote genetic signals for human T-cell leukemia virus type I RNA 3'-end processing , 1991, Journal of virology.

[112]  H. Piwnica-Worms,et al.  Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein. , 1991, Genes & development.

[113]  E. Wahle.  A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation , 1991, Cell.

[114]  Ronald W. Davis,et al.  Polymerase chain reaction mapping of yeast GAL7 mRNA polyadenylation sites demonstrates that 3' end processing in vitro faithfully reproduces the 3' ends observed in vivo , 1991, Nucleic Acids Res..

[115]  B. Cullen,et al.  Effect of RNA secondary structure on polyadenylation site selection. , 1991, Genes & development.

[116]  B. Cullen,et al.  Efficient polyadenylation within the human immunodeficiency virus type 1 long terminal repeat requires flanking U3-specific sequences , 1991, Journal of virology.

[117]  G. Braus,et al.  Different classes of polyadenylation sites in the yeast Saccharomyces cerevisiae. , 1991, Molecular and cellular biology.

[118]  L. Minvielle-Sebastia,et al.  Mutations in the yeast RNA14 and RNA15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein , 1991, Molecular and cellular biology.

[119]  J. Lingner,et al.  Purification and characterization of poly(A) polymerase from Saccharomyces cerevisiae. , 1991, The Journal of biological chemistry.

[120]  J. Nevins,et al.  Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA , 1991, Molecular and cellular biology.

[121]  M. Wickens,et al.  Site-directed ribose methylation identifies 2′-OH groups in polyadenylation substrates critical for AAUAAA recognition and poly(A) addition , 1991, Cell.

[122]  M. L. Peterson,et al.  The developmentally regulated shift from membrane to secreted mu mRNA production is accompanied by an increase in cleavage-polyadenylation efficiency but no measurable change in splicing efficiency , 1991, Molecular and cellular biology.

[123]  R. Pastori,et al.  Coordinate estrogen-regulated instability of serum protein-coding messenger RNAs in Xenopus laevis. , 1991, Molecular Endocrinology.

[124]  C. Moore,et al.  Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation , 1991, Molecular and cellular biology.

[125]  J. Alwine,et al.  The human immunodeficiency virus type 1 polyadenylylation signal: a 3' long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[126]  F. Sherman,et al.  Distinct cis‐acting signals enhance 3′ endpoint formation of CYC1 mRNA in the yeast Saccharomyces cerevisiae. , 1991, The EMBO journal.

[127]  M. Imperiale,et al.  Involvement of long terminal repeat U3 sequences overlapping the transcription control region in human immunodeficiency virus type 1 mRNA 3' end formation , 1991, Molecular and cellular biology.

[128]  Joseph R. Nevins,et al.  The HTLV-I rex response element mediates a novel form of mRNA polyadenylation , 1991, Cell.

[129]  Nick Proudfoot,et al.  Poly(A) signals , 1991, Cell.

[130]  W. Saenger.  Structure and catalytic function of nucleases , 1991 .

[131]  C. Dieckmann,et al.  Yeast CBP1 mRNA 3' end formation is regulated during the induction of mitochondrial function , 1991, Molecular and cellular biology.

[132]  J. Nevins,et al.  Poly(A) site efficiency reflects the stability of complex formation involving the downstream element. , 1991, The EMBO journal.

[133]  J. Manley,et al.  A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. , 1990, Genes & development.

[134]  H. Temin,et al.  The efficiency of RNA 3'-end formation is determined by the distance between the cap site and the poly(A) site in spleen necrosis virus. , 1990, Genes & development.

[135]  J. Richter,et al.  Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF. , 1990, The EMBO journal.

[136]  J. Richter,et al.  Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes , 1990, Molecular and cellular biology.

[137]  M. Wickens.  In the beginning is the end: regulation of poly(A) addition and removal during early development. , 1990, Trends in biochemical sciences.

[138]  R. Jackson,et al.  Do the poly(A) tail and 3′ untranslated region control mRNA translation? , 1990, Cell.

[139]  T. Hohn,et al.  Proximity to the promoter inhibits recognition of cauliflower mosaic virus polyadenylation signal , 1990, Nature.

[140]  D. Carter,et al.  Vasopressin gene expression in the rodent hypothalamus: transcriptional and posttranscriptional responses to physiological stimulation. , 1990, Molecular endocrinology.

[141]  J. Butler,et al.  RNA processing in vitro produces mature 3' ends of a variety of Saccharomyces cerevisiae mRNAs , 1990, Molecular and cellular biology.

[142]  D. Ganem,et al.  Sequences 5' to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses. , 1990, Genes & development.

[143]  M. Wickens,et al.  Polyadenylation of mRNA: minimal substrates and a requirement for the 2' hydroxyl of the U in AAUAAA , 1990, Molecular and cellular biology.

[144]  J. Manley,et al.  A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates , 1990, Molecular and cellular biology.

[145]  M. Wickens,et al.  Polyadenylation-specific complexes undergo a transition early in the polymerization of a poly(A) tail , 1990, Molecular and cellular biology.

[146]  S. Berget,et al.  Exon definition may facilitate splice site selection in RNAs with multiple exons. , 1990, Molecular and cellular biology.

[147]  J. McLauchlan,et al.  Herpes simplex virus induces a processing factor that stimulates poly(A) site usage , 1989, Cell.

[148]  M. Wickens,et al.  Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU. , 1989, Genes & development.

[149]  R. Rickles,et al.  Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes. , 1989, Genes & development.

[150]  J. Nevins,et al.  An ordered pathway of assembly of components required for polyadenylation site recognition and processing. , 1989, Genes & development.

[151]  K. von Figura,et al.  Arylsulfatase A pseudodeficiency: loss of a polyadenylylation signal and N-glycosylation site. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[152]  M. Imperiale,et al.  Sequences upstream of AAUAAA influence poly(A) site selection in a complex transcription unit , 1989, Molecular and cellular biology.

[153]  J. Manley,et al.  Four factors are required for 3'-end cleavage of pre-mRNAs. , 1989, Genes & development.

[154]  J. Alwine,et al.  Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences , 1989, Molecular and cellular biology.

[155]  C. Dieckmann,et al.  The yeast CBP1 gene produces two differentially regulated transcripts by alternative 3'-end formation , 1989, Molecular and cellular biology.

[156]  I. Deckman,et al.  Alterations in the pre-mRNA topology of the bovine growth hormone polyadenylation region decrease poly(A) site efficiency. , 1989, Nucleic acids research.

[157]  Ronald W. Davis,et al.  The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation , 1989, Cell.

[158]  M. Wickens,et al.  Two phases in the addition of a poly(A) tail. , 1989, Genes & development.

[159]  N. Proudfoot,et al.  Definition of an efficient synthetic poly(A) site. , 1989, Genes & development.

[160]  L. Guarente,et al.  Mutational analysis of a yeast transcriptional terminator , 1989 .

[161]  J. Richter,et al.  Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. , 1989, Genes & development.

[162]  L. Smith,et al.  Extranuclear estrogen-regulated destabilization of Xenopus laevis serum albumin mRNA. , 1989, Molecular endocrinology.

[163]  D. Carter,et al.  Independent regulation of neuropeptide mRNA level and poly(A) tail length. , 1989, The Journal of biological chemistry.

[164]  M. L. Peterson,et al.  The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice , 1989, Molecular and cellular biology.

[165]  J. Logan,et al.  Regulation of poly(A) site selection in adenovirus , 1989, Journal of virology.

[166]  G. Christofori,et al.  Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro , 1989, Molecular and cellular biology.

[167]  J. Butler,et al.  RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro. , 1988, Science.

[168]  C. Cole,et al.  Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals , 1988, Molecular and cellular biology.

[169]  R. Deeley,et al.  Estrogen-dependent activation of the avian very low density apolipoprotein II and vitellogenin genes. Transient alterations in mRNA polyadenylation and stability early during induction. , 1988, Journal of molecular biology.

[170]  G. Christofori,et al.  3′ cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP , 1988, Cell.

[171]  W. Schwartz,et al.  Vasopressin mRNA in the suprachiasmatic nuclei: daily regulation of polyadenylate tail length. , 1988, Science.

[172]  J. Majzoub,et al.  The vasopressin mRNA poly(A) tract is unusually long and increases during stimulation of vasopressin gene expression in vivo , 1988, Molecular and cellular biology.

[173]  J. Manley,et al.  Polyadenylation of mRNA precursors. , 1988, Biochimica et biophysica acta.

[174]  M. Wickens,et al.  A functionally redundant downstream sequence in SV40 late pre-mRNA is required for mRNA 3'-end formation and for assembly of a precleavage complex in vitro. , 1988, The Journal of biological chemistry.

[175]  J. Manley,et al.  Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation , 1988, Cell.

[176]  T. Shenk,et al.  A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif , 1988, Cell.

[177]  M. Gehring,et al.  Modified nuclear processing of alpha 1-acid glycoprotein RNA during inflammation. , 1987, The Journal of biological chemistry.

[178]  J. Nevins,et al.  Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development. , 1987, Genes & development.

[179]  N. Proudfoot,et al.  Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit β-globin mRNA 3′ end formation , 1987, Cell.

[180]  R. Axel,et al.  Glucocorticoids enhance stability of human growth hormone mRNA , 1987, Molecular and cellular biology.

[181]  M. Wickens,et al.  Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs , 1987, Molecular and cellular biology.

[182]  M. L. Peterson,et al.  Regulated production of mu m and mu s mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the mu s-mu m intron. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[183]  R P Hart,et al.  Sequences capable of restoring poly(A) site function define two distinct downstream elements. , 1986, The EMBO journal.

[184]  B. Moss,et al.  Transcription of vaccinia virus early genes by enzymes isolated from vaccinia virions terminates downstream of a regulatory sequence , 1986, Cell.

[185]  C. Moore,et al.  Analysis of RNA cleavage at the adenovirus‐2 L3 polyadenylation site. , 1986, The EMBO journal.

[186]  R. Muschel,et al.  Regulation of insulin mRNA abundance and adenylation: dependence on hormones and matrix substrata. , 1986, Molecular and cellular biology.

[187]  P. Sharp,et al.  Accurate cleavage and polyadenylation of exogenous RNA substrate , 1985, Cell.

[188]  J. McLauchlan,et al.  The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini. , 1985, Nucleic acids research.

[189]  S. Orkin,et al.  Thalassemia due to a mutation in the cleavage‐polyadenylation signal of the human beta‐globin gene. , 1985, The EMBO journal.

[190]  S. Goodbourn,et al.  α-Thalassaemia caused by a polyadenylation signal mutation , 1983, Nature.

[191]  F. Sherman,et al.  DNA sequence required for efficient transcription termination in yeast , 1982, Cell.

[192]  David Baltimore,et al.  Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends , 1980, Cell.

[193]  N. Proudfoot,et al.  3′ Non-coding region sequences in eukaryotic messenger RNA , 1976, Nature.