Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice

[1]  J. Moncrieff,et al.  The serotonin theory of depression: a systematic umbrella review of the evidence , 2022, Molecular Psychiatry.

[2]  Aixia Zhang,et al.  Gut Microbiome Composition Linked to Inflammatory Factors and Cognitive Functions in First-Episode, Drug-Naive Major Depressive Disorder Patients , 2022, Frontiers in Neuroscience.

[3]  A. Uitterlinden,et al.  Association of Insulin Resistance and Type 2 Diabetes With Gut Microbial Diversity , 2021, JAMA network open.

[4]  Xiaoqiong Li,et al.  Allobaculum Involves in the Modulation of Intestinal ANGPTLT4 Expression in Mice Treated by High-Fat Diet , 2021, Frontiers in Nutrition.

[5]  H. Shoji,et al.  Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test , 2021, Molecular Brain.

[6]  Wenjun Gao,et al.  The Paraventricular Nucleus of the Thalamus Is an Important Node in the Emotional Processing Network , 2020, Frontiers in Behavioral Neuroscience.

[7]  S. Mazmanian,et al.  The gut microbiota–brain axis in behaviour and brain disorders , 2020, Nature Reviews Microbiology.

[8]  R. Carelli,et al.  Activation of Infralimbic to Nucleus Accumbens Shell Pathway Suppresses Conditioned Aversion in Male But Not Female Rats , 2020, The Journal of Neuroscience.

[9]  A. Starkweather,et al.  Altered Composition of Gut Microbiota in Depression: A Systematic Review , 2020, Frontiers in Psychiatry.

[10]  Y. Kamitani,et al.  Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons , 2020, bioRxiv.

[11]  A. Iwanami,et al.  Gut microbiota and major depressive disorder: A systematic review and meta-analysis. , 2020, Journal of affective disorders.

[12]  Fangyi Chen,et al.  Attenuation of auditory mismatch negativity in serotonin transporter knockout mice with anxiety-related behaviors , 2019, Behavioural Brain Research.

[13]  Shigeyoshi Fujisawa,et al.  Presynaptic dysregulation of the paraventricular thalamic nucleus causes depression-like behavior , 2019, Scientific Reports.

[14]  Xiaosong Hu,et al.  Beneficial effects of ginger on prevention of obesity through modulation of gut microbiota in mice , 2019, European Journal of Nutrition.

[15]  Benjamin R. Arenkiel,et al.  A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues , 2019, Science Advances.

[16]  H. Shoji,et al.  Age‐related behavioral changes from young to old age in male mice of a C57BL/6J strain maintained under a genetic stability program , 2019, Neuropsychopharmacology reports.

[17]  Ahmed A. Metwally,et al.  Serotonin Transporter Deficiency is Associated with Dysbiosis and Changes in Metabolic Function of the Mouse Intestinal Microbiome , 2019, Scientific Reports.

[18]  J. Mann,et al.  Systematic Review of Gut Microbiota and Major Depression , 2019, Front. Psychiatry.

[19]  I. Sora,et al.  Brain hyperserotonemia causes autism-relevant social deficits in mice , 2018, Molecular Autism.

[20]  Lin-lin Bi,et al.  Optogenetic Long-Term Depression Induction in the PVT-CeL Circuitry Mediates Decreased Fear Memory , 2018, Molecular Neurobiology.

[21]  Masahiko Watanabe,et al.  Distribution of Caskin1 protein and phenotypic characterization of its knockout mice using a comprehensive behavioral test battery , 2018, Molecular Brain.

[22]  J. Deussing,et al.  Stress peptides sensitize fear circuitry to promote passive coping , 2018, Molecular Psychiatry.

[23]  Rahim Ullah,et al.  Anterior Paraventricular Thalamus to Nucleus Accumbens Projection Is Involved in Feeding Behavior in a Novel Environment , 2018, Front. Mol. Neurosci..

[24]  J. Trollor,et al.  Anxiety and Depression from Adolescence to Old Age in Autism Spectrum Disorder , 2019, Journal of Autism and Developmental Disorders.

[25]  M. Mizuguchi,et al.  Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory , 2018, PloS one.

[26]  Y. Sanz,et al.  Influence of gut microbiota on neuropsychiatric disorders , 2017, World journal of gastroenterology.

[27]  T. Miyakawa,et al.  Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice , 2017, Scientific Reports.

[28]  K. Sakimura,et al.  Dorsal Forebrain-Specific Deficiency of Reelin-Dab1 Signal Causes Behavioral Abnormalities Related to Psychiatric Disorders , 2017, Cerebral cortex.

[29]  D. Ribeiro,et al.  The blockage of ventromedial hypothalamus CRF type 2 receptors impairs escape responses in the elevated T-maze , 2017, Behavioural Brain Research.

[30]  Yong Nie,et al.  Similar Fecal Microbiota Signatures in Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Patients With Depression. , 2016, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[31]  M. Ota,et al.  Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder. , 2016, Journal of affective disorders.

[32]  John F. Cryan,et al.  May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry , 2016, CNS Drugs.

[33]  J. Veenstra-VanderWeele,et al.  The serotonin system in autism spectrum disorder: From biomarker to animal models , 2016, Neuroscience.

[34]  ゴラム アッバス モハマド.  Comprehensive Behavioral Analysis of Male Ox1r−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior , 2016 .

[35]  A. Aiba,et al.  Comprehensive behavioral phenotyping of a new Semaphorin 3 F mutant mouse , 2016, Molecular Brain.

[36]  T. Sakurai,et al.  Comprehensive Behavioral Analysis of Male Ox1r−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior , 2015, Front. Behav. Neurosci..

[37]  S. Leibowitz,et al.  GABA-induced inactivation of dorsal midline thalamic subregions has distinct effects on emotional behaviors , 2015, Neuroscience Letters.

[38]  O. Howes,et al.  The serotonin transporter in depression: Meta-analysis of in vivo and post mortem findings and implications for understanding and treating depression. , 2015, Journal of affective disorders.

[39]  A. Kakita,et al.  Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus , 2015, Molecular Psychiatry.

[40]  J. Raes,et al.  Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design , 2015, FEMS microbiology reviews.

[41]  Bing Ruan,et al.  Altered fecal microbiota composition in patients with major depressive disorder , 2015, Brain, Behavior, and Immunity.

[42]  Y. Mori,et al.  Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout mice , 2015, Front. Behav. Neurosci..

[43]  K. Kuriki,et al.  Inter- and intra-individual variations in seasonal and daily stabilities of the human gut microbiota in Japanese , 2015, Archives of Microbiology.

[44]  S. Mazmanian,et al.  Review Control of Brain Development, Function, and Behavior by the Microbiome Figure 2. Microbiome Influence on Bbb Integrity , 2022 .

[45]  Jeroen Raes,et al.  How informative is the mouse for human gut microbiota research? , 2015, Disease Models & Mechanisms.

[46]  Jason Tucciarone,et al.  The paraventricular thalamus controls a central amygdala fear circuit , 2014, Nature.

[47]  Shunsuke Takahashi,et al.  Development of a Prokaryotic Universal Primer for Simultaneous Analysis of Bacteria and Archaea Using Next-Generation Sequencing , 2014, PloS one.

[48]  Roberto Sacco,et al.  Blood serotonin levels in autism spectrum disorder: A systematic review and meta-analysis , 2014, European Neuropsychopharmacology.

[49]  Rupert Lanzenberger,et al.  Meta-analysis of molecular imaging of serotonin transporters in major depression , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[50]  D. Murphy,et al.  Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice , 2014, Psychopharmacology.

[51]  P. François,et al.  Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity , 2014, The ISME Journal.

[52]  Keizo Takao,et al.  Contextual and Cued Fear Conditioning Test Using a Video Analyzing System in Mice , 2014, Journal of visualized experiments : JoVE.

[53]  Christopher G. Davey,et al.  Functional brain imaging studies of youth depression: A systematic review☆ , 2013, NeuroImage: Clinical.

[54]  G. Blatt,et al.  Reduced Serotonin Receptor Subtypes in a Limbic and a Neocortical Region in Autism , 2013, Autism research : official journal of the International Society for Autism Research.

[55]  K. Lesch,et al.  5-HTT Deficiency Affects Neuroplasticity and Increases Stress Sensitivity Resulting in Altered Spatial Learning Performance in the Morris Water Maze but Not in the Barnes Maze , 2013, PloS one.

[56]  E. Nestler,et al.  The brain reward circuitry in mood disorders , 2013, Nature Reviews Neuroscience.

[57]  P. Renshaw,et al.  Factors influencing behavior in the forced swim test , 2013, Physiology & Behavior.

[58]  T. Miyakawa,et al.  Immature Dentate Gyrus: An Endophenotype of Neuropsychiatric Disorders , 2013, Neural plasticity.

[59]  Erik Aronesty,et al.  Comparison of Sequencing Utility Programs , 2013 .

[60]  R. Blakely,et al.  A dialogue between the immune system and brain, spoken in the language of serotonin. , 2013, ACS chemical neuroscience.

[61]  G. Sumara,et al.  Gut-derived serotonin is a multifunctional determinant to fasting adaptation. , 2012, Cell metabolism.

[62]  M. Li,et al.  Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats , 2012, PloS one.

[63]  Keizo Takao,et al.  T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice , 2012, Journal of visualized experiments : JoVE.

[64]  A. Torricelli,et al.  5-HT2A receptor activation in the dorsolateral septum facilitates inhibitory avoidance in the elevated T-maze , 2012, Behavioural Brain Research.

[65]  Kathryn R. Cullen,et al.  Toward dysfunctional connectivity: a review of neuroimaging findings in pediatric major depressive disorder , 2011, Brain Imaging and Behavior.

[66]  H. Pape,et al.  Social Defeat: Impact on Fear Extinction and Amygdala-Prefrontal Cortical Theta Synchrony in 5-HTT Deficient Mice , 2011, PloS one.

[67]  C. Huttenhower,et al.  Metagenomic biomarker discovery and explanation , 2011, Genome Biology.

[68]  J. Constantino,et al.  Characterization of Depression in Children With Autism Spectrum Disorders , 2011, Journal of developmental and behavioral pediatrics : JDBP.

[69]  K. Lesch,et al.  Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice , 2011, European Neuropsychopharmacology.

[70]  Natalie L. Trent,et al.  The ventral hippocampus and the lateral septum work in tandem to regulate rats' open-arm exploration in the elevated plus-maze , 2010, Physiology & Behavior.

[71]  T. Miyakawa,et al.  Behavioral profiles of three C57BL/6 substrains , 2010, Neuroscience Research.

[72]  William A. Walters,et al.  QIIME allows analysis of high-throughput community sequencing data , 2010, Nature Methods.

[73]  K. Lesch,et al.  Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood , 2010, Behavioural Brain Research.

[74]  L. Oreland,et al.  Serotonin, genetic variability, behaviour, and psychiatric disorders - a review , 2010, Upsala journal of medical sciences.

[75]  J. Herman,et al.  Neural regulation of endocrine and autonomic stress responses , 2009, Nature Reviews Neuroscience.

[76]  T. Miyakawa,et al.  Elevated Plus Maze for Mice , 2008, Journal of visualized experiments : JoVE.

[77]  J. John Mann,et al.  Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum , 2008, Cell.

[78]  T. Tabira,et al.  Persistent depressive state after chronic stress in rats is accompanied by HPA axis dysregulation and reduced prefrontal dopaminergic neurotransmission , 2008, Pharmacology Biochemistry and Behavior.

[79]  Eric J. Nestler,et al.  The molecular neurobiology of depression , 2008, Nature.

[80]  M. Brandão,et al.  Gabaergic mechanisms of hypothalamic nuclei in the expression of conditioned fear , 2008, Neurobiology of Learning and Memory.

[81]  K. Fukunaga,et al.  Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders , 2008, European Psychiatry.

[82]  D. Sibley,et al.  Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization , 2008, Psychopharmacology.

[83]  K. Kovács,et al.  Measurement of Immediate‐Early Gene Activation‐ c‐fos and Beyond , 2008, Journal of neuroendocrinology.

[84]  A. Cools,et al.  A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders , 2008, Neuroscience.

[85]  J. Crawley,et al.  Behavioral Phenotyping Strategies for Mutant Mice , 2008, Neuron.

[86]  Dennis L. Murphy,et al.  Targeting the murine serotonin transporter: insights into human neurobiology , 2008, Nature Reviews Neuroscience.

[87]  D. Murphy,et al.  Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice , 2007, Brain Research.

[88]  K. Ressler,et al.  Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic , 2007, Nature Neuroscience.

[89]  J. Tiedje,et al.  Naïve Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy , 2007, Applied and Environmental Microbiology.

[90]  D. Murphy,et al.  Hypolocomotion, anxiety and serotonin syndrome‐like behavior contribute to the complex phenotype of serotonin transporter knockout mice , 2007, Genes, brain, and behavior.

[91]  N. Singewald,et al.  Altered Brain Activation Pattern Associated With Drug-Induced Attenuation of Enhanced Depression-Like Behavior in Rats Bred for High Anxiety , 2007, Biological Psychiatry.

[92]  Rachel A. Millstein,et al.  Impaired Stress-Coping and Fear Extinction and Abnormal Corticolimbic Morphology in Serotonin Transporter Knock-Out Mice , 2007, The Journal of Neuroscience.

[93]  Rachel A. Millstein,et al.  Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice , 2006, Neuroscience.

[94]  C. Lowry,et al.  Exposure to high- and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex , 2006, Brain Research Bulletin.

[95]  T. Miyakawa,et al.  Light/dark Transition Test for Mice , 2006, Journal of visualized experiments : JoVE.

[96]  Sanbing Shen,et al.  Increased Expression of the 5-HT Transporter Confers a Low- Anxiety Phenotype Linked to Decreased 5-HT Transmission , 2006, The Journal of Neuroscience.

[97]  D. Murphy,et al.  Are serotonin transporter knockout mice ‘depressed’?: hypoactivity but no anhedonia , 2006, Neuroreport.

[98]  D. Murphy,et al.  Vulnerability to mild predator stress in serotonin transporter knockout mice , 2006, Behavioural Brain Research.

[99]  Dennis L. Murphy,et al.  Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter , 2005, Neuropharmacology.

[100]  A. Andrews,et al.  Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression , 2004, Journal of Neuroscience Methods.

[101]  Qian Li,et al.  Medial Hypothalamic 5-Hydroxytryptamine (5-HT)1A Receptors Regulate Neuroendocrine Responses to Stress and Exploratory Locomotor Activity: Application of Recombinant Adenovirus Containing 5-HT1A Sequences , 2004, The Journal of Neuroscience.

[102]  Klaus-Peter Lesch,et al.  Regional Differences in Extracellular Dopamine and Serotonin Assessed by In Vivo Microdialysis in Mice Lacking Dopamine and/or Serotonin Transporters , 2004, Neuropsychopharmacology.

[103]  J. Piven,et al.  Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice , 2004, Genes, brain, and behavior.

[104]  R. Chambers,et al.  Regulation of affect by the lateral septum: implications for neuropsychiatry , 2004, Brain Research Reviews.

[105]  Rene Hen,et al.  The developmental origins of anxiety , 2004, Nature Reviews Neuroscience.

[106]  Alicja Lerner,et al.  Serotonin transporter: gene, genetic disorders, and pharmacogenetics. , 2004, Molecular interventions.

[107]  J. D. den Boer,et al.  Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[108]  D. Murphy,et al.  Abnormal anxiety‐related behavior in serotonin transporter null mutant mice: the influence of genetic background , 2003, Genes, brain, and behavior.

[109]  Klaus-Peter Lesch,et al.  Mice Lacking the Serotonin Transporter Exhibit 5-HT1A Receptor-Mediated Abnormalities in Tests for Anxiety-like Behavior , 2003, Neuropsychopharmacology.

[110]  B. Kolb,et al.  Do rats have a prefrontal cortex? , 2003, Behavioural Brain Research.

[111]  V. Arango,et al.  Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice , 2003, Biological Psychiatry.

[112]  H. Groenewegen,et al.  The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics , 2003, Neuroscience & Biobehavioral Reviews.

[113]  D. David,et al.  Monoamine metabolism changes following the mouse forced swimming test but not the tail suspension test , 2003, Fundamental & clinical pharmacology.

[114]  C. Wichems,et al.  Brain region‐specific alterations of 5‐HT2A and 5‐HT2C receptors in serotonin transporter knockout mice , 2003, Journal of neurochemistry.

[115]  C. Belzung,et al.  The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. , 2003, European journal of pharmacology.

[116]  S. File,et al.  A review of 25 years of the social interaction test. , 2003, European journal of pharmacology.

[117]  T. Sharp,et al.  Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs , 2003, Biological Psychiatry.

[118]  D. Murphy,et al.  Evaluation of Antidepressant-related Behavioral Responses in Mice Lacking the Serotonin Transporter , 2002, Neuropsychopharmacology.

[119]  D. Murphy,et al.  Exaggerated adrenomedullary response to immobilization in mice with targeted disruption of the serotonin transporter gene. , 2002, Endocrinology.

[120]  K. Berridge,et al.  Positive and Negative Motivation in Nucleus Accumbens Shell: Bivalent Rostrocaudal Gradients for GABA-Elicited Eating, Taste “Liking”/“Disliking” Reactions, Place Preference/Avoidance, and Fear , 2002, The Journal of Neuroscience.

[121]  Jacqueline N. Crawley,et al.  Reduced aggression in mice lacking the serotonin transporter , 2002, Psychopharmacology.

[122]  T. Tabira,et al.  Chronic stress impairs rotarod performance in rats: implications for depressive state , 2002, Pharmacology Biochemistry and Behavior.

[123]  George Paxinos,et al.  The Mouse Brain in Stereotaxic Coordinates , 2001 .

[124]  D. Murphy,et al.  Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[125]  K. Lesch,et al.  Reduction in the Density and Expression, But Not G-Protein Coupling, of Serotonin Receptors (5-HT1A) in 5-HT Transporter Knock-Out Mice: Gender and Brain Region Differences , 2000, The Journal of Neuroscience.

[126]  B. Leonard,et al.  A review of the role of serotonin receptors in psychiatric disorders , 2000, Human psychopharmacology.

[127]  A. A. Reilly,et al.  Habituation of Activity in an Open Field: A Survey of Inbred Strains and F1 Hybrids , 2000, Behavior genetics.

[128]  D. Murphy,et al.  Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. , 2000, American journal of medical genetics.

[129]  D. Murphy,et al.  Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. , 1999, The Journal of pharmacology and experimental therapeutics.

[130]  D. Murphy,et al.  Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. , 1999, American journal of medical genetics.

[131]  M Linnoila,et al.  Role of the serotonin transporter promoter polymorphism in anxiety-related traits. , 1998, Archives of general psychiatry.

[132]  K. Kovács,et al.  Invited review c-Fos as a transcription factor: a stressful (re)view from a functional map , 1998, Neurochemistry International.

[133]  D. Murphy,et al.  Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. , 1998, Molecular pharmacology.

[134]  E H Cook,et al.  Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. , 1998, The American journal of psychiatry.

[135]  Jacqueline N. Crawley,et al.  A Proposed Test Battery and Constellations of Specific Behavioral Paradigms to Investigate the Behavioral Phenotypes of Transgenic and Knockout Mice , 1997, Hormones and Behavior.

[136]  K. Lesch,et al.  Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region , 1996, Science.

[137]  George R. Breese,et al.  Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety , 1996, Brain Research.

[138]  F. Graeff,et al.  Defense reaction elicited by microinjection of kainic acid into the medial hypothalamus of the rat: antagonism by a GABAA receptor agonist. , 1992, Behavioral and neural biology.

[139]  H. Groenewegen,et al.  Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat , 1992, The Journal of comparative neurology.

[140]  S. Cabib,et al.  Behavioral and biochemical changes monitored in two inbred strains of mice during exploration of an unfamiliar environment , 1990, Physiology & Behavior.

[141]  F. Goodwin,et al.  Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines , 1980, Pharmacology Biochemistry and Behavior.

[142]  C. Barnes.  Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. , 1979, Journal of comparative and physiological psychology.

[143]  R. Porsolt,et al.  Behavioral despair in mice: a primary screening test for antidepressants. , 1977, Archives internationales de pharmacodynamie et de therapie.

[144]  W. K. Simmons,et al.  Depression and obesity: evidence of shared biological mechanisms , 2018, Molecular Psychiatry.

[145]  C. Dayas,et al.  Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders. , 2017, Current topics in behavioral neurosciences.

[146]  K. Dong,et al.  Prevotella and Klebsiella proportions in fecal microbial communities are potential characteristic parameters for patients with major depressive disorder. , 2017, Journal of affective disorders.

[147]  H. Müller,et al.  Different patterns of 5-HT receptor and transporter dysfunction in neuropsychiatric disorders – a comparative analysis of in vivo imaging findings , 2016, Reviews in the neurosciences.

[148]  Rob Knight,et al.  UCHIME improves sensitivity and speed of chimera detection , 2011, Bioinform..

[149]  Yasuomi Ouchi,et al.  Brain serotonin and dopamine transporter bindings in adults with high-functioning autism. , 2010, Archives of general psychiatry.

[150]  J. Tack,et al.  REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders , 2007 .

[151]  Rebecca Yang,et al.  Effects of Mild Early Life Stress on Abnormal Emotion-related Behaviors in 5-HTT Knockout Mice , 2007, Behavior genetics.

[152]  J. Rawlins,et al.  T-maze alternation in the rodent , 2006, Nature Protocols.

[153]  J. Crawley,et al.  Behavioral phenotyping of transgenic and knockout mice: practical concerns and potential pitfalls. , 2006, ILAR journal.

[154]  R. Lister.  The use of a plus-maze to measure anxiety in the mouse , 2004, Psychopharmacology.

[155]  B. Thierry,et al.  The tail suspension test: A new method for screening antidepressants in mice , 2004, Psychopharmacology.

[156]  Michel Bourin,et al.  Forced swimming test in mice: a review of antidepressant activity , 2004, Psychopharmacology.

[157]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[158]  D. Murphy,et al.  Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. , 1998, The Journal of clinical psychiatry.