Aging‐related histone modification changes in brain function

[1]  Y. Furukawa,et al.  ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II , 2022, Nature Communications.

[2]  C. Gaiddon,et al.  Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target? , 2022, Cancers.

[3]  Xinxiang Li,et al.  Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer. , 2022, Biochimica et biophysica acta. Reviews on cancer.

[4]  Q. Kong,et al.  The landscape of aging , 2022, Science China Life Sciences.

[5]  J. Qi,et al.  Exploring Methods of Targeting Histone Methyltransferases and Their Applications in Cancer Therapeutics. , 2022, ACS chemical biology.

[6]  W. Sippl,et al.  Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis , 2022, Pharmaceuticals.

[7]  Jingyun Liu,et al.  A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway , 2021, Molecules.

[8]  Sareesh Naduvil Narayanan,et al.  Epigenetic Mechanisms in Memory and Cognitive Decline Associated with Aging and Alzheimer’s Disease , 2021, International Journal of Molecular Sciences.

[9]  Lisheng Liu,et al.  Histone demethylase KDM2A: Biological functions and clinical values (Review). , 2021, Experimental and therapeutic medicine.

[10]  Yue Zhang,et al.  Histone citrullination: a new target for tumors , 2021, Molecular cancer.

[11]  Xueyuan Liu,et al.  Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity , 2021, Aging.

[12]  J. Peça,et al.  The old guard: Age-related changes in microglia and their consequences , 2021, Mechanisms of Ageing and Development.

[13]  O. Gozani,et al.  Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease , 2021, Nature Reviews Drug Discovery.

[14]  C. Shao,et al.  Histone methylation can either promote or reduce cellular radiosensitivity by regulating DNA repair pathways. , 2020, Mutation research.

[15]  P. Korkolopoulou,et al.  Targeting post-translational histone modifying enzymes in glioblastoma. , 2020, Pharmacology & therapeutics.

[16]  S. Vatner,et al.  Healthful aging mediated by inhibition of oxidative stress , 2020, Ageing Research Reviews.

[17]  L. Zhang,et al.  The inhibitory effects of class I histone deacetylases on hippocampal neuroinflammatory regulation in aging mice with postoperative cognitive dysfunction. , 2020, European review for medical and pharmacological sciences.

[18]  X. Liu,et al.  Resveratrol protects retinal ganglion cell axons through regulation of the SIRT1-JNK pathway. , 2020, Experimental eye research.

[19]  Chunfu Wu,et al.  Histone methyltransferase and drug resistance in cancers , 2020, Journal of experimental & clinical cancer research : CR.

[20]  Vishakha Mahajan,et al.  Histone acetylation and the role of histone deacetylases in normal cyclic endometrium , 2020, Reproductive Biology and Endocrinology.

[21]  S. D’Mello Histone deacetylase-3: Friend and foe of the brain , 2020, Experimental biology and medicine.

[22]  Pei Hao,et al.  Two conserved epigenetic regulators prevent healthy ageing , 2020, Nature.

[23]  Mauricio G Martín,et al.  Epigenetic mechanisms related to cognitive decline during aging , 2020, Journal of neuroscience research.

[24]  M. Thakur,et al.  Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice , 2019, Biogerontology.

[25]  T. Kitsukawa,et al.  Single-cell memory trace imaging with immediate-early genes , 2019, Journal of Neuroscience Methods.

[26]  Zhen Yan,et al.  Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer’s disease , 2019, Brain : a journal of neurology.

[27]  P. Baldi,et al.  Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory , 2018, Nature Communications.

[28]  Christopher D. Green,et al.  Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation , 2018, Proceedings of the National Academy of Sciences.

[29]  M. Thakur,et al.  Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging , 2017, Molecular Neurobiology.

[30]  M. Mattson,et al.  NAD+ in Aging: Molecular Mechanisms and Translational Implications. , 2017, Trends in molecular medicine.

[31]  D. Balschun,et al.  Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons. , 2016, Cell reports.

[32]  C. Dotti,et al.  Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons , 2016, Nature Communications.

[33]  L. Overman,et al.  H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus , 2016, The Journal of Neuroscience.

[34]  R. Lührmann,et al.  HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. , 2015, The Journal of clinical investigation.

[35]  P. Sachdev,et al.  Differential expression of sirtuins in the aging rat brain , 2015, Front. Cell. Neurosci..

[36]  B. Tang,et al.  SIRT1 in the brain—connections with aging-associated disorders and lifespan , 2015, Front. Cell. Neurosci..

[37]  C. Gomez-Sanchez,et al.  Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice , 2014, Psychoneuroendocrinology.

[38]  W. Le,et al.  Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson’s disease , 2013, Cell Death and Differentiation.

[39]  P. Hof,et al.  Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction. , 2013, Current Alzheimer research.

[40]  Richard T Dang,et al.  HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation , 2013, The Journal of Neuroscience.

[41]  Christopher D. Green,et al.  Stress‐associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain , 2012, Aging cell.

[42]  Marcelo A. Wood,et al.  HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation , 2010, The Journal of Neuroscience.

[43]  L. Tsai,et al.  A novel pathway regulates memory and plasticity via SIRT1 and miR-134 , 2010, Nature.

[44]  R. Murison,et al.  Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the hippocampus proper , 2006, Pharmacology Biochemistry and Behavior.

[45]  Pravir Kumar,et al.  Histone deacetylase in neuropathology. , 2021, Advances in clinical chemistry.

[46]  E. Nestler,et al.  Drug-activated cells: From immediate early genes to neuronal ensembles in addiction. , 2021, Advances in pharmacology.