Changes in proteoglycan subsystem of cartilage as a result of infrared-laser treatment

Cartilage was exposed to infrared laser treatment of moderate intensity with infrared radiometric temperature control. The time dependences of proteoglycan residue release from cartilage were obtained to the buffer solution and to the solution of proteolytic enzyme tripsin. Histochemical analysis of changes in the cartilage proteoglycan subsystem as a result of infrared laser treatment and tripsin treatment was carried out. It was shown that infrared laser irradiation leads to particular destruction of proteoglycans and proteoglycan aggregates in cartilage and decreases the stability of the proteoglycan subsystem to tripsin.