Renewed Global Partnerships and Redesigned Roadmaps for Rabies Prevention and Control

Canine rabies, responsible for most human rabies deaths, is a serious global public health concern. This zoonosis is entirely preventable, but by focusing solely upon rabies prevention in humans, this “incurable wound” persists at high costs. Although preventing human deaths through canine rabies elimination is feasible, dog rabies control is often neglected, because dogs are not considered typical economic commodities by the animal health sector. Here, we demonstrate that the responsibility of managing rabies falls upon multiple sectors, that a truly integrated approach is the key to rabies elimination, and that considerable progress has been made to this effect. Achievements include the construction of global rabies networks and organizational partnerships; development of road maps, operational toolkits, and a blueprint for rabies prevention and control; and opportunities for scaling up and replication of successful programs. Progress must continue towards overcoming the remaining challenges preventing the ultimate goal of rabies elimination.

[1]  T. Lembo Blueprint for Rabies Prevention and Control , 2013 .

[2]  S. Cleaveland,et al.  Catalysing action against rabies , 2010, Veterinary Record.

[3]  R. Dedmon,et al.  World Rabies Day (September 28, 2010): the continuing effort to ‘make rabies history’ , 2010 .

[4]  Tiziana Lembo,et al.  The Feasibility of Canine Rabies Elimination in Africa: Dispelling Doubts with Data , 2010, PLoS neglected tropical diseases.

[5]  Sally J. Cutler,et al.  Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World , 2010, Emerging infectious diseases.

[6]  M. Gates Human and dog rabies prevention and control , 2010 .

[7]  Margaret Chan,et al.  Working to overcome the global impact of neglected tropical diseases : first WHO report on neglected tropical diseases , 2010 .

[8]  Thomas Müller,et al.  Development of a Mouse Monoclonal Antibody Cocktail for Post-exposure Rabies Prophylaxis in Humans , 2009, PLoS neglected tropical diseases.

[9]  M. Penny,et al.  Transmission dynamics and economics of rabies control in dogs and humans in an African city , 2009, Proceedings of the National Academy of Sciences.

[10]  P. Buchy,et al.  Rabies Situation in Cambodia , 2009, PLoS neglected tropical diseases.

[11]  M. Ratsitorahina,et al.  Dog ecology and demography in Antananarivo, 2007 , 2009, BMC veterinary research.

[12]  P. Vounatsou,et al.  Effectiveness of dog rabies vaccination programmes: comparison of owner-charged and free vaccination campaigns , 2009, Epidemiology and Infection.

[13]  Craig Packer,et al.  Transmission Dynamics and Prospects for the Elimination of Canine Rabies , 2009, PLoS biology.

[14]  R. Ditangco,et al.  A pilot study on the usefulness of information and education campaign materials in enhancing the knowledge, attitude and practice on rabies in rural Sri Lanka. , 2009, Journal of infection in developing countries.

[15]  R. Dedmon,et al.  World Rabies Day outreach to Asia: empowering people through education. , 2009 .

[16]  S. Cleaveland,et al.  Rabies control in rural Africa: evaluating strategies for effective domestic dog vaccination. , 2009, Vaccine.

[17]  Elisabeth Specht Integrated control of neglected zoonotic diseases in Africa. , 2009, Releve epidemiologique hebdomadaire.

[18]  J. Blanton,et al.  Enzootic Rabies Elimination from Dogs and Reemergence in Wild Terrestrial Carnivores, United States , 2008, Emerging infectious diseases.

[19]  B. Quiambao,et al.  Rabies awareness in eight Asian countries. , 2008, Vaccine.

[20]  Jonathan Dushoff,et al.  Rabies Exposures, Post-Exposure Prophylaxis and Deaths in a Region of Endemic Canine Rabies , 2008, PLoS neglected tropical diseases.

[21]  E. Carter Humane Dog Population Management Guidance , 2008, Animal Welfare.

[22]  L. A. Frias,et al.  Rabies‐vaccination Coverage and Profiles of the Owned‐dog Population in Santa Cruz de la Sierra, Bolivia , 2008, Zoonoses and public health.

[23]  J. Deeks,et al.  A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods , 2008, PLoS neglected tropical diseases.

[24]  A. Fooks,et al.  Inferior rabies vaccine quality and low immunization coverage in dogs (Canis familiaris) in China , 2008, Epidemiology and Infection.

[25]  N. Tordo,et al.  Can rabies be eradicated? , 2008, Developments in biologicals.

[26]  Nicholas Johnson,et al.  Towards the elimination of rabies in Eurasia. , 2008, Developments in biologicals.

[27]  B. Dodet An important date in rabies history. , 2007, Vaccine.

[28]  S. Hendrickx,et al.  Current status of human rabies transmitted by dogs in Latin America. , 2007, Cadernos de saude publica.

[29]  C. Hanlon,et al.  World Rabies Day: focusing attention on a neglected disease , 2007, Veterinary Record.

[30]  A. Fooks Rabies — the need for a ‘one medicine’ approach , 2007, Veterinary Record.

[31]  D. Johnston,et al.  Historical Perspective of Rabies in Europe and the Mediterranean Basin , 2007 .

[32]  Marcel Tanner,et al.  Human Benefits of Animal Interventions for Zoonosis Control , 2007, Emerging infectious diseases.

[33]  M. Molyneux,et al.  Rabies Encephalitis in Malaria-Endemic Area, Malawi, Africa , 2007, Emerging infectious diseases.

[34]  Rabies vaccines. WHO position paper. , 2007, Releve epidemiologique hebdomadaire.

[35]  Rabies has its day. , 2007, Lancet. Infectious Diseases (Print).

[36]  Humane cat population management guidance International Companion Animal Management Coalition , 2007 .

[37]  G. Hutton,et al.  Cost‐description of a pilot parenteral vaccination campaign against rabies in dogs in N'Djaména, Chad , 2006, Tropical medicine & international health : TM & IH.

[38]  R. Botta A Review of: “Communicating Public Health Information Effectively: A Guide for Practitioners.” , 2006 .

[39]  S. Cleaveland The control of neglected zoonotic diseases A route to poverty alleviation , 2006 .

[40]  T. Lembo WHO Expert Consultation on rabies. , 2010, World Health Organization technical report series.

[41]  A. Fooks Rabies remains a 'neglected disease'. , 2005, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[42]  M. Meltzer,et al.  Re-evaluating the burden of rabies in Africa and Asia. , 2005, Bulletin of the World Health Organization.

[43]  M. Woolhouse,et al.  Emerging pathogens: the epidemiology and evolution of species jumps , 2005, Trends in Ecology & Evolution.

[44]  D. Pfeiffer,et al.  Vaccination coverage and epidemiological parameters of the owned-dog population in Thungsong District, Thailand. , 2004, Preventive veterinary medicine.

[45]  F A Leighton,et al.  The role of wildlife in emerging and re-emerging zoonoses. , 2004, Revue scientifique et technique.

[46]  E. Holmes,et al.  Viral evolution and the emergence of SARS coronavirus. , 2004, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[47]  Edward C Holmes,et al.  The phylogeography of human viruses , 2004, Molecular ecology.

[48]  T. Kuiken,et al.  Emerging viral infections in a rapidly changing world , 2003, Current Opinion in Biotechnology.

[49]  S. Cleaveland,et al.  A dog rabies vaccination campaign in rural Africa: impact on the incidence of dog rabies and human dog-bite injuries. , 2003, Vaccine.

[50]  Qi Chen,et al.  Generation and evaluation of a high-growth reassortant H9N2 influenza A virus as a pandemic vaccine candidate. , 2003, Vaccine.

[51]  P. Vounatsou,et al.  Coverage of pilot parenteral vaccination campaign against canine rabies in N'Djaména, Chad. , 2003, Bulletin of the World Health Organization.

[52]  C. Berg,et al.  Abortion surveillance--United States, 1999. , 2002, Morbidity and mortality weekly report. Surveillance summaries.

[53]  Rabies In Asia STRATEGIES FOR THE CONTROL AND ELIMINATION OF , 2002 .

[54]  E. Fèvre,et al.  Estimating human rabies mortality in the United Republic of Tanzania from dog bite injuries. , 2002, Bulletin of the World Health Organization.

[55]  T. Mueller,et al.  Field trial with oral vaccination of dogs against rabies in the Philippines , 2001, BMC infectious diseases.

[56]  L. H. Taylor,et al.  Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[57]  M E Woolhouse,et al.  Risk factors for human disease emergence. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[58]  B. Aylward,et al.  When is a disease eradicable? 100 years of lessons learned. , 2000, American journal of public health.

[59]  D. Heymann,et al.  Public health implications of emerging zoonoses. , 2000, Revue scientifique et technique.

[60]  Bobby Milstein,et al.  Framework for program evaluation in public health , 1999 .

[61]  Jeffrey R. Harris,et al.  Framework for program evaluation in public health. , 1999, MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports.

[62]  M. Slater Theory and method in health audience segmentation. , 1996, Journal of health communication.

[63]  J. Childs,et al.  Evaluation of a canine rabies vaccination campaign and characterization of owned-dog populations in the Philippines. , 1996, The Southeast Asian journal of tropical medicine and public health.

[64]  C. Dye,et al.  Immunization coverage required to prevent outbreaks of dog rabies. , 1996, Vaccine.

[65]  Perry Bd Dog ecology in eastern and southern Africa: implications for rabies control. , 1993 .

[66]  A. Kappeler,et al.  The ecology of dogs and canine rabies: a selective review. , 1993, Revue scientifique et technique.

[67]  B. Perry Dog ecology in eastern and southern Africa: implications for rabies control. , 1993, The Onderstepoort journal of veterinary research.

[68]  WHO Expert Committee on Rabies. , 1992, World Health Organization technical report series.

[69]  F. Meslin,et al.  Economics of human and canine rabies elimination: guidelines for programme orientation. , 1990, Bulletin of the World Health Organization.

[70]  K. Bögel,et al.  Incidence of rabies and post-exposure treatment in developing countries. , 1986, Bulletin of the World Health Organization.

[71]  J. Higginson,et al.  Report of a workshop , 1982 .

[72]  J. Gerring A case study , 2011, Technology and Society.

[73]  A. B. Lees,et al.  Communication Channels. , 1961, Science.