论文信息 - A NEW SYNTHESIS OF 2-(6-CARBOXYHEXYL)CYCLOPENT-2-EN-1-ONE, A PROSTANOID SYNTHON

A NEW SYNTHESIS OF 2-(6-CARBOXYHEXYL)CYCLOPENT-2-EN-1-ONE, A PROSTANOID SYNTHON

A new synthesis of the title compound (1), an useful intermediate in the synthesis of various prostanoids, is described which involves the acid-catalyzed cyclopropane rearrangement of 9-cyclopropyl-9-oxononanoic acid (7) as a key step. The cyclopropyl ketone 7 was prepared via the three steps from cyclopropyl methyl ketone.

T. Nakai | M. Okawara | E. Wada

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