Drug properties affecting aerosol behavior.
暂无分享,去创建一个
[1] J. Crapo,et al. Allometric relationships of cell numbers and size in the mammalian lung. , 1992, American journal of respiratory cell and molecular biology.
[2] M. Newhouse,et al. Optimal delivery of aerosols from metered dose inhalers. , 1981, Chest.
[3] I Gonda,et al. Aerosols for delivery of therapeutic and diagnostic agents to the respiratory tract. , 1990, Critical reviews in therapeutic drug carrier systems.
[4] Lewis S. Schanker,et al. Absorption of Disodium Cromoglycate from the Rat Lung: Evidence of Carrier Transport , 1974 .
[5] R. Effros. Osmotic extraction of hypotonic fluid from the lungs. , 1974, The Journal of clinical investigation.
[6] L S Schanker,et al. Absorption of aerosolized drugs from the rat lung. , 1983, Drug metabolism and disposition: the biological fate of chemicals.
[7] J. Charpin,et al. Interaction between corticosteroids and beta 2-agonists in acute asthma. , 1982, European journal of respiratory diseases. Supplement.
[8] Scherer Pw. Mucus transport by cough. , 1981 .
[9] T. Devereux,et al. Xenobiotic metabolism by isolated pulmonary cells. , 1989, Pharmacology & therapeutics.
[10] T. T. Mercer. 2 – Properties of Aerosols , 1973 .
[11] D. Wall,et al. SK&F 110679: comparison of absorption following oral or respiratory administration , 1994 .
[12] K H Kilburn,et al. Particles causing lung disease. , 1984, Environmental health perspectives.
[13] R. Schlesinger,et al. Clearance from the respiratory tract. , 1985, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[14] L S Schanker,et al. Drug absorption from the lung. , 1978, Biochemical pharmacology.
[15] G. Patrick,et al. Measurement of mucociliary clearance from the trachea of conscious and anesthetized rats. , 1977, Journal of applied physiology: respiratory, environmental and exercise physiology.
[16] B. Jonson,et al. Pulmonary clearance of inhaled 99mTc-DTPA: effects of surfactant depletion by lung lavage. , 1987, Journal of applied physiology.
[17] E. Crandall,et al. Heteropore populations of bullfrog alveolar epithelium. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.
[18] B. Goodman,et al. Alveolar epithelium permeability to small solutes: developmental changes. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.
[19] G. Rudolf,et al. Intercomparison of Experimental Regional Aerosol Deposition Data , 1989 .
[20] B. Jonson,et al. Pulmonary clearance of inhaled 99mTc-DTPA: effect of surfactant depletion in rabbits. , 1986, Clinical physiology.
[21] M. Svartengren,et al. Clearance of particles from small ciliated airways. , 1997, Experimental lung research.
[22] G. Ferron. The size of soluble aerosol particles as a function of the humidity of the air. Application to the human respiratory tract , 1977 .
[23] J. Gaddum,et al. 5-Hydroxytryptamine; pharmacological action and destruction in perfused lungs. , 1953, Quarterly journal of experimental physiology and cognate medical sciences.
[24] F. Komada,et al. Intratracheal delivery of insulin Absorption from solution and aerosol by rat lung , 1992 .
[25] J. J. Batenburg. Surfactant phospholipids: synthesis and storage. , 1992, The American journal of physiology.
[26] B. D. Beck,et al. An in vivo hamster bioassay to assess the toxicity of particulates for the lungs. , 1982, Toxicology and applied pharmacology.
[27] M Lippmann,et al. Interspecies comparisons of particle deposition and mucociliary clearance in tracheobronchial airways. , 1984, Journal of toxicology and environmental health.
[28] J. Gil. Number and distribution of plasmalemmal vesicles in the lung. , 1983, Federation proceedings.
[29] E. Schneeberger. STRUCTURE OF INTERCELLULAR JUNCTIONS IN DIFFERENT SEGMENTS OF THE INTRAPULMONARY VASCULATURE * , 1982, Annals of the New York Academy of Sciences.
[30] Richardson Ps,et al. The control of airway mucus secretion. , 1987 .
[31] M. Svartengren,et al. Deposition and clearance in large and small airways in chronic bronchitis. , 1996, Experimental lung research.
[32] M. Dolovich. Rationale for spacer use in children , 1997, Pediatric pulmonology. Supplement.
[33] Pramod K. Gupta,et al. Contemporary approaches in aerosolized drug delivery to the lung , 1991 .
[34] P. Corey,et al. Survey of the clinical use of pressurized aerosol inhalers. , 1979, Canadian Medical Association journal.
[35] Robert Gelein,et al. Role of the alveolar macrophage in lung injury: studies with ultrafine particles. , 1992 .
[36] D. Bowden. Macrophages, dust, and pulmonary diseases. , 1987, Experimental lung research.
[37] E. Schneeberger,et al. Epithelial solute permeability, ion transport and tight junction morphology in the developing lung of the fetal lamb , 1981, The Journal of physiology.
[38] P. König,et al. Spacer devices used with metered-dose inhalers. Breakthrough or gimmick? , 1985, Chest.
[39] J. Goerke,et al. Alveolar subphase pH in the lungs of anesthetized rabbits. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[40] F. Morén,et al. Aerosols in Medicine: Principles, Diagnosis and Therapy , 1993 .
[41] J. Verhoef,et al. Pulmonary surfactant protein A enhances the host-defense mechanism of rat alveolar macrophages. , 1990, American journal of respiratory cell and molecular biology.
[42] Martin P. Ward,et al. EARLY EXPERIENCE WITH A VERTICAL SPINNING-DISC NEBULISER , 1981, The Lancet.
[43] J. Ferin. Pulmonary retention and clearance of particles. , 1994, Toxicology letters.
[44] M. Sanderson,et al. Ciliary activity of cultured rabbit tracheal epithelium: beat pattern and metachrony. , 1981, Journal of cell science.
[45] I. Gonda. Drugs administered directly into the respiratory tract: modeling of the duration of effective drug levels. , 1988, Journal of pharmaceutical sciences.
[46] P. Byron. Some Future Perspectives for Unit Dose Inhalation Aerosols , 1986 .
[47] M. Clem,et al. Retention of microspheres in the rat lung after intratracheal instillation. , 1981, Environmental research.
[48] Effros Rm,et al. Measurements of pulmonary epithelial permeability in vivo. , 1983, The American review of respiratory disease.
[49] M. R. Bailey,et al. An interspecies comparison of the lung clearance of inhaled monodisperse cobalt oxide particles - part I: objectives and summary of results , 1989 .
[50] E. Reynolds,et al. Permeability of lung capillaries and alveoli to non‐electrolytes in the foetal lamb. With an Appendix , 1971, The Journal of physiology.
[51] J Yu,et al. Pulmonary drug delivery: physiologic and mechanistic aspects. , 1997, Critical reviews in therapeutic drug carrier systems.
[52] M. Bundgaard,et al. The three-dimensional organization of tight junctions in a capillary endothelium revealed by serial-section electron microscopy. , 1984, Journal of ultrastructure research.
[53] J. Sturgess,et al. An organ culture study of the effect of drugs on the secretory activity of the human bronchial submucosal gland. , 1972, Clinical science.
[54] L. Schanker,et al. Absorption of cardiac glycosides from the rat respiratory tract. , 1973, The Journal of pharmacology and experimental therapeutics.
[55] P. Macpherson,et al. Surfactant proteins A (SP-A) and D (SP-D): levels in human amniotic fluid and localization in the fetal membranes. , 1994, Biochimica et biophysica acta.
[56] R. Effros,et al. Role of perfusion and diffusion in 14CO2 exchange in the rabbit lung. , 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.
[57] M. Dolovich,et al. Lung dose, distribution, and clinical response to therapeutic aerosols , 1993 .
[58] Shepherd Vl. The role of the respiratory burst of phagocytes in host defense. , 1986 .
[59] A. Ryrfeldt,et al. Biotransformation of the topical glucocorticoids budesonide and beclomethasone 17α,21‐dipropionate in human liver and lung homogenate , 1984, The Journal of pharmacy and pharmacology.
[60] S. Hawgood. Pulmonary surfactant apoproteins: a review of protein and genomic structure. , 1989, The American journal of physiology.
[61] M. Svartengren,et al. Retention of particles on the first bifurcation and the trachea of rabbits. , 1981, Bulletin europeen de physiopathologie respiratoire.
[62] P. Barnes,et al. Autoradiographic localization of autonomic receptors in airway smooth muscle. Marked differences between large and small airways. , 1983, The American review of respiratory disease.
[63] R. Crystal,et al. The Lung: Scientific Foundations , 1991 .
[64] J. Patton. Inhalation delivery of therapeutic peptides and proteins. , 1999, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.
[65] Günter Oberdörster,et al. Lung Clearance of Inhaled Insoluble and Soluble Particles , 1988 .
[66] J. Brain,et al. Mechanisms, measurement, and significance of lung macrophage function. , 1992, Environmental health perspectives.
[67] J. Burton,et al. Absorption of Antibiotics from the Rat Lung 1 , 1974, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[68] W. Foster,et al. Disassociation in the mucociliary function of central and peripheral airways of asymptomatic smokers. , 1985, The American review of respiratory disease.
[69] T J Clark,et al. Effect of beclomethasone dipropionate delivered by aerosol in patients with asthma. , 1972, Lancet.
[70] G. S. Davis,et al. Defense mechanisms of the respiratory membrane. , 1977, The American review of respiratory disease.
[71] R. Effros,et al. Pulmonary epithelial sieving of small solutes in rat lungs. , 1988, Journal of applied physiology.
[72] D. Rogers,et al. Neural control of airway mucus secretion. , 1990, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[73] M. Youdim,et al. THE METABOLISM OF 5‐HYDROXYTRYPTAMINE AND β‐PHENYL‐ETHYLAMINE IN PERFUSED RAT LUNG AND IN VITRO , 1979 .
[74] T. O'riordan,et al. Changes in mucociliary clearance during acute exacerbations of asthma. , 1991, The American review of respiratory disease.
[75] P. Valberg,et al. Breathing patterns influence aerosol deposition sites in excised dog lungs. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.
[76] S J Enna,et al. Absorption of saccharides and urea from the rat lung. , 1972, The American journal of physiology.
[77] E. Lock,et al. NADPH: cytochrome P-450 reductase in olfactory epithelium. Relevance to cytochrome P-450-dependent reactions. , 1986, Biochemical Journal.
[78] C. Cox,et al. Intratracheal instillation versus intratracheal-inhalation of tracer particles for measuring lung clearance function. , 1997, Experimental lung research.
[79] M. Genghini,et al. Role of surfactant in alveolar defence against inhaled particles. , 1989, Respiration; international review of thoracic diseases.
[80] M. Johnson,et al. Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids. , 1996, The Journal of allergy and clinical immunology.
[81] S. Clarke,et al. Therapeutic aerosols 2-Drugs available by the inhaled route , 2022 .
[82] H. Oestern,et al. Communicating-occluding junction complexes in the alveolar epithelium. A freeze-fracture study. , 1980, The American review of respiratory disease.
[83] V L Roggli,et al. Cell number and distribution in human and rat airways. , 1994, American journal of respiratory cell and molecular biology.
[84] R. McClellan,et al. Retention of monodisperse or polydisperse aluminosilicate particles inhaled by dogs, rats, and mice. , 1983, Toxicology and applied pharmacology.
[85] A. Häkkinen,et al. The effect of breathing frequency on deposition of drug aerosol using an inhalation-synchronized dosimeter in healthy adults. , 1999, Clinical physiology.
[86] J. Patton,et al. Drug delivery via the respiratory tract. , 1994, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.
[87] P. Byron. Prediction of drug residence times in regions of the human respiratory tract following aerosol inhalation. , 1986, Journal of pharmaceutical sciences.
[88] R. F. Cook,et al. Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease , 1994, The Journal of cell biology.
[89] D. Underhill,et al. The effect of various aerosols on the response of guinea pigs to sulfur dioxide. , 1968, Archives of environmental health.
[90] P. Oh,et al. Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. , 1994, The Journal of biological chemistry.
[91] M. Svartengren,et al. Tracheobronchial deposition and clearance in small airways in asthmatic subjects. , 1996, The European respiratory journal.
[92] M. R. Bailey,et al. The long-term clearance kinetics of insoluble particles from the human lung. , 1982, The Annals of occupational hygiene.
[93] Marianne Geiser,et al. Surfactant and inhaled particles in the conducting airways: Structural, stereological, and biophysical aspects , 1993, Microscopy research and technique.
[94] C. Lafortuna,et al. Beclomethasone dipropionate does not affect mucociliary clearance in patients with chronic obstructive lung disease. , 1986, Respiration; international review of thoracic diseases.
[95] J D Wilson,et al. Respiratory tract deposition of ultrafine particles in subjects with obstructive or restrictive lung disease. , 1990, Chest.
[96] M. Karnovsky,et al. Substructure of Intercellular Junctions in Freeze‐Fractured Alveolar‐Capillary Membranes of Mouse Lung , 1976, Circulation research.
[97] S. Enna,et al. Absorption of drugs from the rat lung. , 1972, The American journal of physiology.
[98] J. Patton,et al. Mechanisms of macromolecule absorption by the lungs , 1996 .
[99] J. Palmer,et al. Metabolic effects of salbutamol: comparison of aerosol and intravenous administration. , 1977, British medical journal.
[100] W. Foster,et al. Measurement of tracheal and bronchial mucus velocities in man: relation to lung clearance. , 1980, Journal of applied physiology: respiratory, environmental and exercise physiology.
[101] M. Dolovich. New delivery systems and propellants. , 1999, Canadian respiratory journal.
[102] L S Schanker,et al. Species comparison of drug absorption from the lung after aerosol inhalation or intratracheal injection. , 1986, Drug metabolism and disposition: the biological fate of chemicals.
[103] R. Schlesinger,et al. Comparative deposition of inhaled aerosols in experimental animals and humans: a review. , 1985, Journal of toxicology and environmental health.
[104] R. V. Lourenço,et al. Clinical Aerosols: II. Therapeutic Aerosols. , 1982, Archives of internal medicine.
[105] Aerosol deposition modeling using ACSL. , 1999, Drug and chemical toxicology.
[106] A. Sugar,et al. Characterization of Murine Bronchoalveolar Macrophage Respiratory Burst: Comparison of Soluble and Particulate Stimuli , 1988, Journal of leukocyte biology.
[107] D. Pavia,et al. Deposition of pressurized suspension aerosols inhaled through extension devices. , 1981, The American review of respiratory disease.
[108] M. Svartengren,et al. Human deposition and clearance of 6-micron particles inhaled with an extremely low flow rate. , 1995, Experimental lung research.
[109] B. Muggenburg,et al. Disposition of 3-, 7-, and 13-μm microspheres instilled into lungs of dogs , 1984 .
[110] G. Oberdörster,et al. Pulmonary retention of ultrafine and fine particles in rats. , 1992, American journal of respiratory cell and molecular biology.
[111] J. Patton,et al. (D) Routes of delivery: Case studies , 1992 .
[112] C. Serabjit-Singh,et al. The pulmonary uptake, accumulation, and metabolism of xenobiotics. , 1985, Annual review of pharmacology and toxicology.
[113] J. Sciarra,et al. Simulated respiratory system for in vitro evaluation of two inhalation delivery systems using selected steroids. , 1978, Journal of pharmaceutical sciences.