Implantable radiators for cancer therapy by microwave hyperthermia

The treatment of cancer by the combined effects of heat and radiation or chemotherapy is a promising procedure which has attracted wide interest. Microwave radiation is one of the most useful techniques for creating thermal fields in tissue but its use is limited by the rapid attenuation of microwaves in propagation through the body. Consequently, the design of microwave radiators which can be hypodermically inserted into tissue or introduced via a body orifice has been undertaken by a number of investigators. We review this work, the results of in vitro and in vivo animal tests, and the present status and outlook for patient treatment by this method.

[1]  B. L. C. B.Sc.,et al.  XXIII. Propagation of electromagnetic disturbances along a thin Wire, in a horizontally stratified medium , 1950 .

[2]  T. Senior.  Impedance boundary conditions for imperfectly conducting surfaces , 1960 .

[3]  A. Baños.  Dipole radiation in the presence of a conducting half-space , 1966 .

[4]  James R. Wait.  Electromagnetic Wave Propagation Along a Buried Insulated Wire , 1972 .

[5]  Ronold W. P. King,et al.  The insulated monopole: Admittance and junction effects , 1975 .

[6]  J. Bigu-del-Blanco,et al.  The design of a monopole radiator to investigate the effect of microwave radiation in biological systems. , 1977, Journal of bioengineering.

[7]  H. Bassen,et al.  Evaluation of an implantable electric‐field probe within finite simulated tissues , 1977 .

[8]  F. Sterzer,et al.  Microwave-induced hyperthermia in cancer treatment: apparatus and preliminary results. , 1978, International journal of radiation oncology, biology, physics.

[9]  Electromagnetic Syringe , 1978, IEEE Transactions on Biomedical Engineering.

[10]  J. Strohbehn,et al.  LOCAL MICROWAVE HYPERTHERMIA AS A TREATMENT OF CANCER , 1979 .

[11]  J. Walsh,et al.  Cancer therapy with localized hyperthermia using an invasive microwave system. , 1979, The Journal of microwave power.

[12]  K Tabuse,et al.  A new operative procedure of hepatic surgery using a microwave tissue coagulator. , 1979, Nihon geka hokan. Archiv fur japanische Chirurgie.

[13]  F. Sterzer,et al.  Microwave Applicators for Localized Hyperthermia Treatment of Malignant Tumors , 1980, 1980 IEEE MTT-S International Microwave symposium Digest.

[14]  E. Grant,et al.  A broad band microwave applicator for heating tumours. , 1980, The British journal of radiology.