Considerations When Performing Arthrodesis in the Scleroderma Hand

Background Hand deformities secondary to scleroderma can limit activities of daily living and be associated with substantial disability. This study aimed to evaluate the outcomes following arthrodesis performed to treat digital contractures secondary to scleroderma. Methods We performed a retrospective review of all patients with scleroderma who underwent arthrodesis by a single surgeon from 2015 to 2020. We collected demographic information, operative variables, and outcomes variables. Our primary outcome was occurrence of any postoperative complication, which we defined to include wound dehiscence, digital ischemia, malunion, nonunion, cellulitis, and osteomyelitis. We calculated descriptive statistics and performed all analyses at the joint level. Results We identified 9 patients who underwent arthrodesis of 19 joints. All patients were women with a mean age of 55.3 years. At the time of surgery, most patients were taking disease-modifying antirheumatic drugs (DMARDs). Kirschner wires (K-wires) were used in most cases (n = 18), 15 of which were removed uneventfully at an average of 4.8 months after surgery. With a mean follow-up time of 15.4 months, the overall complication rate was 5.3% (n = 1). This patient developed digital ischemia in 1 of 4 operative digits, which became gangrenous and required amputation. Conclusions Our study suggests that arthrodesis can be performed safely in the scleroderma hand, even when patients are taking DMARDs. Given the uneventful K-wire removal in all joints and the high risk of exposure of buried hardware in this population, we recommend nonpermanent placement of K-wires. Hand surgeons may consider arthrodesis in the scleroderma hand before proceeding to revision amputation.

[1]  S. Beldner,et al.  Scleroderma of the Hand: Evaluation and Treatment. , 2020, The Journal of the American Academy of Orthopaedic Surgeons.

[2]  Scott D. Lifchez,et al.  The Management of Perioperative Immunosuppressant Medications for Rheumatoid Arthritis During Elective Hand Surgery. , 2020, The Journal of hand surgery.

[3]  K. Guppy,et al.  Impact of Chronic DMARD therapy in Patients with Rheumatoid Arthritis undergoing Surgery of the Craniovertebral Junction: A Multi-center Retrospective Study. , 2020, Spine.

[4]  S. Lifchez,et al.  The Scleroderma Hand: Manifestations of Disease and Approach to Management. , 2018, The Journal of hand surgery.

[5]  C. Melone,et al.  Articular Surgery of the Ischemic Hand in Systemic Scleroderma: A Vascular Basis for Arthrodesis and Arthroplasty. , 2018, The Journal of hand surgery.

[6]  D. Khanna,et al.  Hand Impairment in Systemic Sclerosis: Various Manifestations and Currently Available Treatment , 2016, Current Treatment Options in Rheumatology.

[7]  Alexander D. Choo,et al.  Nonrheumatoid Inflammatory Arthroses of the Hand and Wrist. , 2015, The Journal of hand surgery.

[8]  S. Proudman,et al.  Musculoskeletal Manifestations of Systemic Sclerosis. , 2015, Rheumatic diseases clinics of North America.

[9]  V. Denaro,et al.  Current Concepts in the Management of Rheumatoid Hand , 2015, International journal of rheumatology.

[10]  S. Lam,et al.  The impact of steroids, methotrexate, and biologics on clinical and radiographic outcomes in patients with rheumatoid arthritis undergoing fusions at the craniovertebral junction , 2015, Journal of craniovertebral junction & spine.

[11]  J. Poole,et al.  Evidence-based management of hand and mouth disability in a woman living with diffuse systemic sclerosis (scleroderma). , 2013, Physiotherapy Canada. Physiotherapie Canada.

[12]  S. Adami,et al.  Digital Amputation in Systemic Sclerosis: Prevalence and Clinical Associations. A Retrospective Longitudinal Study , 2012, The Journal of Rheumatology.

[13]  M. Matucci-Cerinic,et al.  Characteristics of Joint Involvement and Relationships with Systemic Inflammation in Systemic Sclerosis: Results from the EULAR Scleroderma Trial and Research Group (EUSTAR) Database , 2010, The Journal of Rheumatology.

[14]  S. Schwartz,et al.  Is scleroderma a vasculopathy? , 2009, Current rheumatology reports.

[15]  A. Anandacoomarasamy,et al.  Reconstructive hand surgery for scleroderma joint contractures. , 2007, The Journal of hand surgery.

[16]  P. Kopylov,et al.  WOUND HEALING AFTER HAND SURGERY IN PATIENTS WITH SYSTEMIC SCLEROSIS—A RETROSPECTIVE ANALYSIS OF 41 OPERATIONS IN 19 PATIENTS , 2007, The Journal of hand surgery, European volume.

[17]  E. Bogoch,et al.  Surgery of the hand in patients with systemic sclerosis: outcomes and considerations. , 2005, The Journal of rheumatology.

[18]  B. Jolles,et al.  Surgery of the Hand in Severe Systemic Sclerosis , 2004, Journal of hand surgery.

[19]  U. Nordenskiöld,et al.  Daily activities and hand function in women with scleroderma , 2004, Scandinavian journal of rheumatology.

[20]  S. Beldner,et al.  Surgical management of the hand in scleroderma. , 1999, Current opinion in rheumatology.

[21]  T. Medsger,et al.  Surgery for scleroderma of the hand. , 1987, The Journal of hand surgery.

[22]  R. Winkelmann,et al.  Surgery for sclerodactylia of the hand. Experience with six cases. , 1969, The Journal of bone and joint surgery. American volume.

[23]  D. Wise Suppressed wound healing in a patient with rheumatoid arthritis taking leflunomide (arava). , 2011, The Permanente journal.