A Verbal/Social Autopsy (VASA) Child Mortality Inquiry to Investigate Under-Five Mortality Determinants in Slums of Karachi, Pakistan:A Mix Methods Interventional Study

Background Pakistan stands along top ten countries responsible for two-third of global child mortality burden. To improve Child Mortality (CM) estimates in Pakistan, there is an exigent need to understand the in-depth reasoning behind mortalities. In Pakistan, the data on cause-ofdeath (CoD) for a large number of child mortalities in Pakistan is either not available or not suitable for use. Pakistan uses an alternative technique called Verbal autopsy (VA). Since VA only determines the biological cause of death (BCoD), and does not capture multitude of other modifiable social, cultural and health system determinants, it has a limited importance. Such non-biological determinants are captured by another technique i.e. Social Autopsy (SA). Objective By integrating VA with SA, extended set of mortality related determinants will be explored, in addition to strengthening death notification coverage and assigning CoD in such missed out mortalities. Method Under the working group of Health Advocacy Council for Women and Children (HACWC) in collaboration with Child Registry of Pakistan (CROP), mixed method (QUAN-QUAL) interventional study will be carried out in urban-slums of Karachi city using VASA-integrated under-five mortality investigative technique. Parents of dead children will be interviewed. Second stage of study will be followed by qualitative interviews with different cadres of stakeholders. Expected Outcomes By focusing the specific determinants related to case-management and care-seeking process (identified by The Pathway to Survival Framework-TPtoSF) an in-depth understanding of related determinants can be achieved, which will help in crafting potential interventions required to limit the barriers that increase the chances of CM in developing nations.

[1]  K. Dalal,et al.  Exploration of social factors associated to maternal deaths due to haemorrhage and convulsions: Analysis of 28 social autopsies in rural Bangladesh , 2016, BMC Health Services Research.

[2]  K. Dalal,et al.  Social Autopsy of maternal, neonatal deaths and stillbirths in rural Bangladesh: qualitative exploration of its effect and community acceptance , 2016, BMJ Open.

[3]  W. Low,et al.  Social Autopsy is a Dire Need for Investigating Child Mortality in Pakistan , 2016 .

[4]  R. Black,et al.  Journal of Health Global , 2022 .

[5]  H. Kalter,et al.  Social determinants of child mortality in Niger: Results from the 2012 National Verbal and Social Autopsy Study , 2016, Journal of global health.

[6]  H. Kalter,et al.  Verbal/Social Autopsy in Niger 2012–2013: A new tool for a better understanding of the neonatal and child mortality situation , 2016, Journal of global health.

[7]  M. Dibley,et al.  Iron/folic acid supplementation during pregnancy prevents neonatal and under-five mortality in Pakistan: propensity score matched sample from two Pakistan Demographic and Health Surveys , 2016, Global health action.

[8]  H. Kalter,et al.  Social autopsy study identifies determinants of neonatal mortality in Doume, Nguelemendouka and Abong–Mbang health districts, Eastern Region of Cameroon , 2015, Journal of global health.

[9]  R. Black,et al.  Direct estimates of national neonatal and child cause–specific mortality proportions in Niger by expert algorithm and physician–coded analysis of verbal autopsy interviews , 2015, Journal of global health.

[10]  Z. Bhutta,et al.  The community-based delivery of an innovative neonatal kit to save newborn lives in rural Pakistan: design of a cluster randomized trial , 2014, BMC Pregnancy and Childbirth.

[11]  Magdi S. Mahmoud,et al.  Role of Delays , 2014 .

[12]  W. Carlo,et al.  Validation of Verbal Autopsy Tool for Ascertaining the Causes of Stillbirth , 2013, PloS one.

[13]  R. Black,et al.  Increased use of social autopsy is needed to improve maternal, neonatal and child health programmes in low-income countries. , 2012, Bulletin of the World Health Organization.

[14]  J. Cecatti,et al.  The role of delays in severe maternal morbidity and mortality: expanding the conceptual framework , 2012, Reproductive health matters.

[15]  R. Black,et al.  Social autopsy for maternal and child deaths: a comprehensive literature review to examine the concept and the development of the method , 2011, Population health metrics.

[16]  T. Williams,et al.  Social autopsy: INDEPTH Network experiences of utility, process, practices, and challenges in investigating causes and contributors to mortality , 2011, Population health metrics.

[17]  P. Byass,et al.  A lost cause? Extending verbal autopsy to investigate biomedical and socio-cultural causes of maternal death in Burkina Faso and Indonesia. , 2010, Social science & medicine.

[18]  G. Pariyo,et al.  Using the three delays model to understand why newborn babies die in eastern Uganda , 2010, Tropical medicine & international health : TM & IH.

[19]  M. Koblinsky,et al.  Verbal Autopsy of Maternal Deaths in Two Districts of Pakistan—Filling Information Gaps , 2009, Journal of health, population, and nutrition.

[20]  C. Hurt,et al.  Diagnostic accuracy of verbal autopsies in ascertaining the causes of stillbirths and neonatal deaths in rural Ghana. , 2008, Paediatric and perinatal epidemiology.

[21]  G. Darmstadt,et al.  Validation of verbal autopsy to determine the cause of 137 neonatal deaths in Karachi, Pakistan. , 2003, Paediatric and perinatal epidemiology.

[22]  W. Mosley,et al.  An Analytical Framework for the Study of Child Survival in Developing Countries , 1984 .

[23]  R. D'souza,et al.  ROLE OF HEALTH-SEEKING BEHAVIOUR IN CHILD MORTALITY IN THE SLUMS OF KARACHI, PAKISTAN , 2002, Journal of Biosocial Science.

[24]  R. Waldman,et al.  The evolution of child health programmes in developing countries: from targeting diseases to targeting people. , 2000, Bulletin of the World Health Organization.

[25]  D. Maine,et al.  Too far to walk: maternal mortality in context. , 1991, Social science & medicine.

[26]  D. Marsh,et al.  Cause-specific child mortality in a mountainous community in Pakistan by verbal autopsy. , 1993, JPMA. The Journal of the Pakistan Medical Association.