Comparison of acquired bilateral nevus of Ota-like macules in men and women.

BACKGROUND The clinical and histopathological characteristics of acquired bilateral nevus of Ota-like macules in men are poorly documented due to its rarity. AIMS To compare the clinical and histopathological characteristics of acquired bilateral nevus of Ota-like macules in men with the condition in women. METHODS We studied 11 men and 62 women, all with a clinical diagnosis of acquired bilateral nevus of Ota-like macules. Biopsies were taken from 5 men and 10 women and their clinical and histopathological features were compared. RESULTS The most frequently affected site in men was the forehead [8 (73%) out of 11 patients]. Lesions on the forehead were more common in men than women (P = 0.001). In contrast to women, there was no apparent tendency of the lesions to become more blue with age in men. Concurrent melasma was observed in 14 (23%) out of 62 women, but not in men. Extra-facial acquired dermal melanocytosis was noted in 2 (18%) out of 11 men and in none of the 62 women. CONCLUSION Significant differences were noted between men and women in the appearance of concurrent pigmentary lesions and the distribution of lesions. Extra-facial acquired dermal melanocytosis was noted in men.

[1]  T. Nishikawa,et al.  Acquired dermal melanocytosis of the face and extremities , 2016, Clinical and experimental dermatology.

[2]  Hong Li,et al.  A population-based study of acquired bilateral nevus-of-Ota-like macules in Shanghai, China. , 2011, The Journal of investigative dermatology.

[3]  You Chan Kim,et al.  Histopathological features of acquired dermal melanocytosis. , 2010, European journal of dermatology : EJD.

[4]  R. Ruan,et al.  Androgen, estrogen and progesterone receptors in acquired bilateral nevus of Ota‐like macules , 2010, Pigment cell & melanoma research.

[5]  Sung Bin Cho,et al.  Treatment of acquired bilateral nevus of Ota‐like macules (Hori's nevus) using 1064‐nm Q‐switched Nd:YAG laser with low fluence , 2009, International journal of dermatology.

[6]  Sandy S Tsao,et al.  Acquired bilateral nevus of Ota-like macules (Hori nevus): etiologic and therapeutic considerations. , 2009, Journal of the American Academy of Dermatology.

[7]  T. Kawakami,et al.  Acquired dermal melanocytosis naevus of Ota-like macules on the face and extremities lesions in a young Japanese woman. , 2009, Acta dermato-venereologica.

[8]  L. Requena,et al.  Late‐onset Ito’s nevus: An uncommon acquired dermal melanocytosis , 2007, Journal of cutaneous pathology.

[9]  P. Ang,et al.  Characteristics of Hori naevus: a prospective analysis , 2006, The British journal of dermatology.

[10]  M. Mizoguchi,et al.  Acquired symmetrical dermal melanocytosis (naevus of Hori) developing after aggravated atopic dermatitis , 2005, The British journal of dermatology.

[11]  Mu-Hyoung Lee,et al.  Acquired, Bilateral Nevus of Ota-like Macules (ABNOM) Associated with Ota's Nevus: Case Report , 2004, Journal of Korean medical science.

[12]  Eun-So Lee,et al.  Comparison of Characteristics of Acquired Bilateral Nevus of Ota-like Macules and Nevus of Ota According to Therapeutic Outcome , 2004, Journal of Korean medical science.

[13]  R. Phelps,et al.  Acquired dermal melanocytosis in an African-American: A case report. , 2000, Journal of the American Academy of Dermatology.

[14]  M. Kawashima,et al.  Dormant melanocytes in the dermis: do dermal melanocytes of acquired dermal melanocytosis exist from birth? , 1998, The British journal of dermatology.

[15]  Y. Kubota,et al.  Clinical, pathological, and etiologic aspects of acquired dermal melanocytosis. , 1997, Pigment cell research.

[16]  M. Yamakawa,et al.  [Generalised type of acquired dermal melanocytosis]. , 1991, Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology.

[17]  P. Cooper,et al.  Late-onset nevus of Ota. , 1991, Cutis.

[18]  A. Hidano Acquired, bilateral nevus of Ota-like macules. , 1985, Journal of the American Academy of Dermatology.