Linkage Analysis of Qualitative Traits

[1]  Johanna M Seddon,et al.  Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration , 2006, Nature Genetics.

[2]  Michael Boehnke,et al.  Efficient study designs for test of genetic association using sibship data and unrelated cases and controls. , 2006, American journal of human genetics.

[3]  G. Abecasis,et al.  Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers. , 2005, American journal of human genetics.

[4]  D. Schorderet,et al.  Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy. , 2005, American journal of human genetics.

[5]  Jurg Ott,et al.  Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. , 2005, American journal of human genetics.

[6]  Michael Boehnke,et al.  Joint Modeling of Linkage and Association: Identifying Snps Responsible for a Linkage Signal , 2022 .

[7]  J. Gilbert,et al.  Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration , 2005, Science.

[8]  J. Ott,et al.  Complement Factor H Polymorphism in Age-Related Macular Degeneration , 2005, Science.

[9]  J. Haines,et al.  Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions. , 2004, American journal of human genetics.

[10]  Silke Schmidt,et al.  Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12 , 2004, BMC Genetics.

[11]  Carl D Langefeld,et al.  Ordered subset analysis in genetic linkage mapping of complex traits , 2004, Genetic epidemiology.

[12]  G. Abecasis,et al.  Age-Related Macular Degeneration: A High-Resolution Genome Scan for Susceptibility Loci in a Population Enriched for Late-Stage Disease , 2004 .

[13]  S. Santangelo,et al.  A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions. , 2003, American journal of human genetics.

[14]  T. Matise,et al.  Age-related macular degeneration--a genome scan in extended families. , 2003, American journal of human genetics.

[15]  A. Bird,et al.  Towards an understanding of age-related macular disease , 2003, Eye.

[16]  D. Weeks,et al.  A survey of affected-sibship statistics for nonparametric linkage analysis. , 2001, American journal of human genetics.

[17]  D J Schaid,et al.  Regression models for linkage heterogeneity applied to familial prostate cancer. , 2001, American journal of human genetics.

[18]  D. Weeks,et al.  A full genome scan for age-related maculopathy. , 2000, Human molecular genetics.

[19]  Daniel F. Gudbjartsson,et al.  Allegro, a new computer program for multipoint linkage analysis , 2000, Nature genetics.

[20]  J. Olson.  A general conditional-logistic model for affected-relative-pair linkage studies. , 1999, American journal of human genetics.

[21]  C. Klaver,et al.  The genetics of age-related macular degeneration. , 1999, Molecular vision.

[22]  S. Bull,et al.  Analysis of affected sib pairs, with covariates--with and without constraints. , 1999, American journal of human genetics.

[23]  A Hofman,et al.  Genetic risk of age-related maculopathy. Population-based familial aggregation study. , 1998, Archives of ophthalmology.

[24]  T. Matise,et al.  Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q. , 1998, Archives of ophthalmology.

[25]  J R O'Connell,et al.  PedCheck: a program for identification of genotype incompatibilities in linkage analysis. , 1998, American journal of human genetics.

[26]  M. Boehnke,et al.  Genetic association mapping based on discordant sib pairs: the discordant-alleles test. , 1998, American journal of human genetics.

[27]  W. Ewens,et al.  A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. , 1998, American journal of human genetics.

[28]  N J Cox,et al.  Allele-sharing models: LOD scores and accurate linkage tests. , 1997, American journal of human genetics.

[29]  D. Curtis,et al.  Use of siblings as controls in case‐control association studies , 1997, Annals of human genetics.

[30]  J M Seddon,et al.  Familial aggregation of age-related maculopathy. , 1997, American journal of ophthalmology.

[31]  L Kruglyak,et al.  Parametric and nonparametric linkage analysis: a unified multipoint approach. , 1996, American journal of human genetics.

[32]  J. O’Connell,et al.  The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set–recoding and fuzzy inheritance , 1995, Nature Genetics.

[33]  E. Lander,et al.  Complete multipoint sib-pair analysis of qualitative and quantitative traits. , 1995, American journal of human genetics.

[34]  Johannes R. Vingerling,et al.  The prevalence of age-related maculopathy in the Rotterdam Study. , 1995, Ophthalmology.

[35]  A. Whittemore,et al.  A class of tests for linkage using affected pedigree members. , 1994, Biometrics.

[36]  A A Schäffer,et al.  Faster sequential genetic linkage computations. , 1993, American journal of human genetics.

[37]  W. Ewens,et al.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). , 1993, American journal of human genetics.

[38]  P. Holmans,et al.  Asymptotic properties of affected-sib-pair linkage analysis. , 1993, American journal of human genetics.

[39]  R. Klein,et al.  Prevalence of age-related maculopathy. The Beaver Dam Eye Study. , 1992, Ophthalmology.

[40]  N. Risch.  Linkage strategies for genetically complex traits. II. The power of affected relative pairs. , 1990, American journal of human genetics.

[41]  L. Tsui,et al.  Erratum: Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA , 1989, Science.

[42]  L. Tsui,et al.  Erratum: Identification of the Cystic Fibrosis Gene: Genetic Analysis , 1989, Science.

[43]  J. Riordan,et al.  Identification of the Cystic Fibrosis Gene : Chromosome Walking and Jumping Author ( s ) : , 2008 .

[44]  M. Koenig,et al.  Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals , 1987, Cell.

[45]  K. Liang,et al.  Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests under Nonstandard Conditions , 1987 .

[46]  E. Lander,et al.  Construction of multilocus genetic linkage maps in humans. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[47]  K. Lange,et al.  An algorithm for automatic genotype elimination. , 1987, American journal of human genetics.

[48]  C. Bonaïti‐pellié,et al.  Effects of misspecifying genetic parameters in lod score analysis. , 1986, Biometrics.

[49]  J. Ott,et al.  Strategies for multilocus linkage analysis in humans. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[50]  A. Young,et al.  A polymorphic DNA marker genetically linked to Huntington's disease , 1983, Nature.

[51]  D. Rubin,et al.  Maximum likelihood from incomplete data via the EM - algorithm plus discussions on the paper , 1977 .

[52]  J. Ott,et al.  A computer program for linkage analysis of general human pedigrees. , 1976, American journal of human genetics.

[53]  E A Thompson,et al.  The estimation of pairwise relationships , 1975, Annals of human genetics.

[54]  J. Ott.  Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. , 1974, American journal of human genetics.

[55]  R. C. Elandt-Johnson.  Probability models and statistical methods in genetics , 1972 .

[56]  R. Elston,et al.  A general model for the genetic analysis of pedigree data. , 1971, Human heredity.

[57]  N. Morton.  Sequential tests for the detection of linkage. , 1955, American journal of human genetics.

[58]  L. Penrose.  THE DETECTION OF AUTOSOMAL LINKAGE IN DATA WHICH CONSIST OF PAIRS OF BROTHERS AND SISTERS OF UNSPECIFIED PARENTAGE , 1935 .

[59]  G. Abecasis,et al.  Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.

[60]  R C Elston,et al.  Lods, wrods, and mods: The interpretation of lod scores calculated under different models , 1994, Genetic epidemiology.

[61]  R. Klein,et al.  The Beaver Dam Eye Study. Retinopathy in adults with newly discovered and previously diagnosed diabetes mellitus. , 1992, Ophthalmology.

[62]  K. Lange,et al.  Programs for pedigree analysis: Mendel, Fisher, and dGene , 1988, Genetic epidemiology.

[63]  G. Lathrop,et al.  Construction of human linkage maps: Likelihood calculations for multilocus linkage analysis , 1986, Genetic epidemiology.

[64]  K. Lange,et al.  Extensions to pedigree analysis. V. Optimal calculation of Mendelian likelihoods. , 1983, Human heredity.

[65]  Robert C. Elston,et al.  Extensions to Pedigree Analysis , 1975 .

[66]  L. Baum,et al.  An inequality and associated maximization technique in statistical estimation of probabilistic functions of a Markov process , 1972 .

[67]  John A. Nelder,et al.  A Simplex Method for Function Minimization , 1965, Comput. J..