The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.
暂无分享,去创建一个
[1] P. Richardson,et al. vRel is an inactive member of the Rel family of transcriptional activating proteins , 1991, Journal of virology.
[2] P. Baeuerle,et al. The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity. , 1990, Genes & development.
[3] T. Gilmore. NF-κB, KBF1, dorsal, and related matters , 1990, Cell.
[4] B Sollner-Webb,et al. High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. , 1984, Nucleic acids research.
[5] H. Temin,et al. v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells , 1988, Journal of virology.
[6] J. Garnier,et al. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. , 1978, Journal of molecular biology.
[7] P. Y. Chou,et al. Prediction of the secondary structure of proteins from their amino acid sequence. , 2006 .
[8] T. Hunter,et al. The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain , 1990, Molecular and cellular biology.
[9] Vincent Bours,et al. Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs , 1990, Nature.
[10] G. Nolan,et al. Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal , 1990, Cell.
[11] S. McKnight,et al. Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. , 1988, Genes & development.
[12] G. Nolan,et al. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide , 1991, Cell.
[13] J. Leatherwood,et al. An amino-terminal fragment of GAL4 binds DNA as a dimer. , 1989, Journal of molecular biology.
[14] Mark Ptashne,et al. Gene regulation by proteins acting nearby and at a distance , 1986, Nature.
[15] S. McKnight,et al. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. , 1988, Science.
[16] P. Baeuerle,et al. NF‐kappa B contacts DNA by a heterodimer of the p50 and p65 subunit. , 1991, The EMBO journal.
[17] W. D. Cress,et al. Critical structural elements of the VP16 transcriptional activation domain. , 1991, Science.
[18] Kevin Struhl,et al. Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast , 1987, Cell.
[19] A. Israël,et al. Inhibition of transcription factors belonging to the rel/NF‐kappa B family by a transdominant negative mutant. , 1991, The EMBO journal.
[20] P. Silver,et al. Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[21] R. Roeder,et al. Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[22] E. Winnacker,et al. The NF-ϰB transcription factor induces DNA bending which is modulated by its 65-kD subunit , 1990 .
[23] A. Israël,et al. A common positive trans-acting factor binds to enhancer sequences in the promoters of mouse H-2 and beta 2-microglobulin genes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[24] U. Zabel,et al. Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA , 1990, Cell.
[25] T. Hunter,et al. c-rel activates but v-rel suppresses transcription from kappa B sites. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[26] I. Verma,et al. The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation. , 1991, Genes & development.
[27] S. Ruben,et al. Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B. , 1991, Science.
[28] M. Ptashne,et al. Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit , 1987, Nature.
[29] Jun Ma,et al. GAL4-VP16 is an unusually potent transcriptional activator , 1988, Nature.
[30] A. Israël,et al. Processing of the precursor of NF-κB by the HIV-1 protease during acute infection , 1991, Nature.
[31] M. Wigler,et al. Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor , 1978, Cell.
[32] J. Maizel,et al. Enhanced graphic matrix analysis of nucleic acid and protein sequences. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[33] D. Baltimore,et al. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. , 1988, Science.
[34] M. Ptashne. How eukaryotic transcriptional activators work , 1988, Nature.
[35] N. Rice,et al. A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon. , 1989, Oncogene.
[36] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[37] R. Hay,et al. Interaction of enhancer-binding protein EBP1 (NF-kappa B) with the human immunodeficiency virus type 1 enhancer , 1990, Journal of virology.
[38] K. Kao,et al. Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[39] P. Baeuerle. The inducible transcription activator NF-κB: regulation by distinct protein subunits , 1991 .
[40] Urban Mb,et al. The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences. , 1991 .
[41] R. Tjian,et al. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. , 1989, Science.
[42] D. Baltimore,et al. A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB. , 1989, Genes & development.
[43] R. Steward,et al. Dorsoventral pattern formation in Drosophila: signal transduction and nuclear targeting. , 1991, Trends in genetics : TIG.
[44] D. Baltimore,et al. Oligonucleotide that binds nuclear factor NF-kappa B acts as a lymphoid-specific and inducible enhancer element. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[45] D. Baltimore,et al. NF-kappa B protein purification from bovine spleen: nucleotide stimulation and binding site specificity. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[46] M. Levine,et al. The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in drosophila , 1991, Cell.
[47] D. Hatat,et al. TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B‐like enhancer binding activity which displaces constitutive factors. , 1989, The EMBO journal.
[48] A. Israël,et al. The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product , 1990, Cell.
[49] C. Scheidereit,et al. Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha. , 1991, Proceedings of the National Academy of Sciences of the United States of America.