Early electron microscopic observations of synaptic structures in the cerebral cortex: a view of the contributions made by George Gray (1924–1999)

The first clear account of synaptic structures in the cerebral cortex was provided by George Gray in 1959. Here we look at the background to this study, which established some clear structural distinctions between synaptic types, and enquire about the extent to which these distinctions can be related to contemporary knowledge of synaptic organization.

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