Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution.

[1]  Wen-Hsiung Li,et al.  Nonrandomness of point mutation as reflected in nucleotide substitutions in pseudogenes and its evolutionary implications , 2005, Journal of Molecular Evolution.

[2]  Zhongming Zhao,et al.  Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome. , 2002, Genome research.

[3]  Anthony Kerlavage,et al.  The Celera Discovery System. , 2002, Nucleic acids research.

[4]  W S Watkins,et al.  Population genomics: a bridge from evolutionary history to genetic medicine. , 2001, Human molecular genetics.

[5]  M. Daly,et al.  High-resolution haplotype structure in the human genome , 2001, Nature Genetics.

[6]  C. Burge,et al.  Assessment of the total number of human transcription units. , 2001, Genomics.

[7]  Justin C. Fay,et al.  Positive and negative selection on the human genome. , 2001, Genetics.

[8]  Pui-Yan Kwok,et al.  Single-nucleotide polymorphisms in the public domain: how useful are they? , 2001, Nature Genetics.

[9]  L. Jin,et al.  Worldwide Dna Sequence Variation in a 10-kilobase Noncoding Region on Human Chromosome 22 Materials and Methods Dna Samples. Sixty-four Individuals Were Collected Worldwide from 16 Populations in Four Major Geographic Areas, including 20 , 2022 .

[10]  C. Fizames,et al.  Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence , 2000, Nature Genetics.

[11]  John Quackenbush,et al.  Gene Index analysis of the human genome estimates approximately 120,000 genes , 2000, Nature Genetics.

[12]  T. Jukes,et al.  The neutral theory of molecular evolution. , 2000, Genetics.

[13]  Toshimichi Ikemura,et al.  Codon usage tabulated from international DNA sequence databases: status for the year 2000 , 2000, Nucleic Acids Res..

[14]  N. Shen,et al.  Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis , 1999, Nature Genetics.

[15]  Henrik Kaessmann,et al.  DNA sequence variation in a non-coding region of low recombination on the human X chromosome , 1999, Nature Genetics.

[16]  Peter D. Keightley,et al.  High genomic deleterious mutation rates in hominids , 1999, Nature.

[17]  E. Lander,et al.  Characterization of single-nucleotide polymorphisms in coding regions of human genes , 1999, Nature Genetics.

[18]  E. Boerwinkle,et al.  DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene , 1998, Nature Genetics.

[19]  C. Nusbaum,et al.  Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. , 1998, Science.

[20]  N Risch,et al.  The Future of Genetic Studies of Complex Human Diseases , 1996, Science.

[21]  D. Labie,et al.  Molecular Evolution , 1991, Nature.

[22]  Wen-Hsiung Li,et al.  Low nucleotide diversity in man. , 1991, Genetics.

[23]  D. Mccormick.  Sequence the Human Genome , 1986, Bio/Technology.

[24]  M. Nei,et al.  Mathematical model for studying genetic variation in terms of restriction endonucleases. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[25]  G. A. Watterson.  On the number of segregating sites in genetical models without recombination. , 1975, Theoretical population biology.