Patterns and predictors of ADHD persistence into adulthood: Results from the National Comorbidity Survey Replication

BACKGROUND— Despite growing interest in adult ADHD, little is known about predictors of persistence of childhood cases into adulthood. METHODS— A retrospective assessment of childhood ADHD, childhood risk factors, and a screen for adult ADHD were included in a sample of 3197 18–44 year old respondents in the National Comorbidity Survey Replication (NCS-R). Blinded adult ADHD clinical reappraisal interviews were administered to a sub-sample of respondents. Multiple imputation (MI) was used to estimate adult persistence of childhood ADHD. Logistic regression was used to study retrospectively reported childhood predictors of persistence. Potential predictors included socio-demographics, childhood ADHD severity, childhood adversity, traumatic life experiences, and comorbid DSM-IV child-adolescent disorders (anxiety, mood, impulse-control, and substance disorders). RESULTS— 36.3% of respondents with retrospectively assessed childhood ADHD were classified by blinded clinical interviews as meeting DSM-IV criteria for current ADHD. Childhood ADHD

[1]  L. Adler Measurement and Diagnosis of Adult ADHD: An Analysis of Expanded Symptom Criteria From the Adult ADHD Clinical Diagnostic Scale (ACDS) , 2010 .

[2]  S. Faraone,et al.  Molecular genetics of attention deficit hyperactivity disorder. , 2010, The Psychiatric clinics of North America.

[3]  Lynne Stokes Introduction to Variance Estimation , 2008 .

[4]  Danielle N. Pappas ADHD Rating Scale-IV: Checklists, Norms, and Clinical Interpretation , 2006 .

[5]  R. Kessler,et al.  The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. , 2006, The American journal of psychiatry.

[6]  M. Reuter,et al.  Inferring candidate genes for Attention Deficit Hyperactivity Disorder (ADHD) assessed by the World Health Organization Adult ADHD Self-Report Scale (ASRS) , 2006, Journal of Neural Transmission.

[7]  Frank B Hu,et al.  Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men. , 2004, The American journal of clinical nutrition.

[8]  S. Wannamethee,et al.  Cardiovascular disease incidence and mortality in older men with diabetes and in men with coronary heart disease , 2004, Heart.

[9]  M. Black,et al.  Measurement of Three Major Subtypes of Child Neglect , 2004, Child maltreatment.

[10]  L. Adler,et al.  Diagnosis and evaluation of adults with attention-deficit/hyperactivity disorder. , 2004, The Psychiatric clinics of North America.

[11]  T. B. Üstün,et al.  The World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) , 2004, International journal of methods in psychiatric research.

[12]  Ronald C Kessler,et al.  The National Comorbidity Survey Replication (NCS‐R): background and aims , 2004, International journal of methods in psychiatric research.

[13]  Olga V. Demler,et al.  The US National Comorbidity Survey Replication (NCS‐R): design and field procedures , 2004, International journal of methods in psychiatric research.

[14]  Joseph Biederman,et al.  Gender effects on Attention-Deficit/Hyperactivity disorder in adults, revisited , 2004, Biological Psychiatry.

[15]  R. Barkley,et al.  Young adult follow-up of hyperactive children: antisocial activities and drug use. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[16]  Jochen Hardt,et al.  Validity of adult retrospective reports of adverse childhood experiences: review of the evidence. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[17]  W. Pelham,et al.  Psychopathology and substance abuse in parents of young children with attention-deficit/hyperactivity disorder. , 2003, Journal of the American Academy of Child and Adolescent Psychiatry.

[18]  A. Angold,et al.  Continuous Performance Test Performance in a Normative Epidemiological Sample , 2003, Journal of abnormal child psychology.

[19]  S. Faraone,et al.  Does stimulant treatment lead to substance use disorders? , 2003, The Journal of clinical psychiatry.

[20]  S. West,et al.  Atomoxetine in adults with ADHD: two randomized, placebo-controlled studies , 2003, Biological Psychiatry.

[21]  E. Galili-Weisstub,et al.  Attention deficit and hyperactivity disorder: review of genetic association studies. , 2003, The Israel journal of psychiatry and related sciences.

[22]  R. Barkley,et al.  Young Adult Follow-Up of Hyperactive Children: Self-Reported Psychiatric Disorders, Comorbidity, and the Role of Childhood Conduct Problems and Teen CD , 2002, Journal of abnormal child psychology.

[23]  R. Barkley,et al.  The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder. , 2002, Journal of abnormal psychology.

[24]  J. Kagan,et al.  Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. , 2001, Archives of general psychiatry.

[25]  B. Peterson,et al.  Prospective, longitudinal study of tic, obsessive-compulsive, and attention-deficit/hyperactivity disorders in an epidemiological sample. , 2001, Journal of the American Academy of Child and Adolescent Psychiatry.

[26]  C. Gillberg,et al.  Natural outcome of ADHD with developmental coordination disorder at age 22 years: a controlled, longitudinal, community-based study. , 2000, Journal of the American Academy of Child and Adolescent Psychiatry.

[27]  M. Monuteaux,et al.  Assessing symptoms of attention deficit hyperactivity disorder in children and adults: which is more valid? , 2000, Journal of consulting and clinical psychology.

[28]  R. Schachar,et al.  Use of self-ratings in the assessment of symptoms of attention deficit hyperactivity disorder in adults. , 2000, The American journal of psychiatry.

[29]  S. Pliszka Patterns of psychiatric comorbidity with attention-deficit/hyperactivity disorder. , 2000, Child and adolescent psychiatric clinics of North America.

[30]  L. Scahill,et al.  Epidemiology of ADHD in school-age children. , 2000, Child and adolescent psychiatric clinics of North America.

[31]  M. Monuteaux,et al.  Attention-deficit disorder and conduct disorder in girls: evidence for a familial subtype , 2000, Biological Psychiatry.

[32]  S. Faraone,et al.  Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. , 2000, The American journal of psychiatry.

[33]  M. Monuteaux,et al.  Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder , 2000, Genetic epidemiology.

[34]  G. Canino,et al.  Parent and child contributions to diagnosis of mental disorder: are both informants always necessary? , 1999, Journal of the American Academy of Child and Adolescent Psychiatry.

[35]  Myron Genel,et al.  Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents , 1998 .

[36]  R. Klein,et al.  Adult psychiatric status of hyperactive boys grown up. , 1998, The American journal of psychiatry.

[37]  S. Faraone,et al.  Diagnostic continuity between child and adolescent ADHD: findings from a longitudinal clinical sample. , 1998, Journal of the American Academy of Child and Adolescent Psychiatry.

[38]  S. Young,et al.  Substance-dependent, conduct-disordered adolescent males: severity of diagnosis predicts 2-year outcome. , 1998, Drug and alcohol dependence.

[39]  S. Pliszka Comorbidity of attention-deficit/hyperactivity disorder with psychiatric disorder: an overview. , 1998, The Journal of clinical psychiatry.

[40]  A. Schell,et al.  A prospective study of hyperactive boys with conduct problems and normal boys: adolescent and adult criminality. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[41]  S. Faraone,et al.  Adolescent outcome of boys with attention-deficit/hyperactivity disorder and social disability: results from a 4-year longitudinal follow-up study. , 1997, Journal of consulting and clinical psychology.

[42]  Christopher G. Davis,et al.  The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: A family history study , 1997, British Journal of Psychiatry.

[43]  P. Hazell The overlap of attention deficit hyperactivity disorder with other common mental disorders , 1997, Journal of paediatrics and child health.

[44]  R. Barkley Advancing age, declining ADHD. , 1997, The American journal of psychiatry.

[45]  M. Rutter,et al.  Retrospective reporting of childhood adversity: issues in assessing long-term recall. , 1997, Journal of personality disorders.

[46]  R. Barkley,et al.  Attention deficit hyperactivity disorder adults: comorbidities and adaptive impairments. , 1996, Comprehensive psychiatry.

[47]  J. C. Hill,et al.  Age-dependent decline of attention deficit hyperactivity disorder. , 1996, The American journal of psychiatry.

[48]  D. Mennin,et al.  A prospective 4-year follow-up study of attention-deficit hyperactivity and related disorders. , 1996, Archives of general psychiatry.

[49]  S. Faraone,et al.  Predictors of persistence and remission of ADHD into adolescence: results from a four-year prospective follow-up study. , 1996, Journal of the American Academy of Child and Adolescent Psychiatry.

[50]  Brooks Applegate,et al.  Developmental change in attention-deficit hyperactivity disorder in boys: A four-year longitudinal study , 1995, Journal of abnormal child psychology.

[51]  S. Faraone,et al.  Family-environment risk factors for attention-deficit hyperactivity disorder. A test of Rutter's indicators of adversity. , 1995, Archives of general psychiatry.

[52]  D. Fergusson,et al.  Predictive validity of categorically and dimensionally scored measures of disruptive childhood behaviors. , 1995, Journal of the American Academy of Child and Adolescent Psychiatry.

[53]  S. Faraone,et al.  High risk for attention deficit hyperactivity disorder among children of parents with childhood onset of the disorder: a pilot study. , 1995, The American journal of psychiatry.

[54]  J. Biederman,et al.  DSM-IV field trials for attention deficit hyperactivity disorder in children and adolescents. , 1994, The American journal of psychiatry.

[55]  R. Kessler,et al.  Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. , 1994, Archives of general psychiatry.

[56]  R. Klein,et al.  Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. , 1993, Archives of general psychiatry.

[57]  G. Weiss,et al.  Hyperactive Children Grown Up: ADHD in Children, Adolescents, and Adults , 1993 .

[58]  R. Barkley,et al.  The adolescent outcome of hyperactive children: predictors of psychiatric, academic, social, and emotional adjustment. , 1993, Journal of the American Academy of Child and Adolescent Psychiatry.

[59]  I. Gotlib,et al.  Psychopathology and early experience: a reappraisal of retrospective reports. , 1993, Psychological bulletin.

[60]  K. Lindem,et al.  Unrecognized attention-deficit hyperactivity disorder in adults presenting for outpatient psychotherapy. , 1992, Journal of child and adolescent psychopharmacology.

[61]  S. Lippmann,et al.  Alcohol abuse and attention deficit disorder. , 1983, The Journal of clinical psychiatry.

[62]  J. Schlesselman,et al.  Case-Control Studies: Design, Conduct, Analysis , 1982 .

[63]  N C Andreasen,et al.  The family history method using diagnostic criteria. Reliability and validity. , 1977, Archives of general psychiatry.