UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality.

[1]  A. Kowaltowski,et al.  Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity , 2008, Aging cell.

[2]  J. Timmons,et al.  Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist. , 2008, American journal of physiology. Endocrinology and metabolism.

[3]  E. Pastalkova,et al.  Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance. , 2008, American journal of physiology. Endocrinology and metabolism.

[4]  J. Wess,et al.  Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality. , 2008, American journal of physiology. Heart and circulatory physiology.

[5]  T. Bengtsson,et al.  Unexpected evidence for active brown adipose tissue in adult humans. , 2007, American journal of physiology. Endocrinology and metabolism.

[6]  J. Ukropec,et al.  UCP1-independent Thermogenesis in White Adipose Tissue of Cold-acclimated Ucp1-/- Mice* , 2006, Journal of Biological Chemistry.

[7]  B. Cannon,et al.  UCP1 is essential for adaptive adrenergic nonshivering thermogenesis. , 2006, American journal of physiology. Endocrinology and metabolism.

[8]  B. Kahn,et al.  Diet-induced Obesity Alters AMP Kinase Activity in Hypothalamus and Skeletal Muscle* , 2006, Journal of Biological Chemistry.

[9]  J. Nedergaard,et al.  Cold‐induced expression of the VEGF gene in brown adipose tissue is independent of thermogenic oxygen consumption , 2005, FEBS letters.

[10]  Y. Wang,et al.  UCP1 deficiency increases susceptibility to diet‐induced obesity with age , 2005, Aging cell.

[11]  M. Benchimol,et al.  The Thermogenic Activity of Rat Brown Adipose Tissue and Rabbit White Muscle Ca2 + ‐ATPase , 2005, IUBMB life.

[12]  J. Montani,et al.  The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation , 2004, FEBS letters.

[13]  Y. Deshaies,et al.  Peroxisome Proliferator-Activated Receptor γ Agonism Increases the Capacity for Sympathetically Mediated Thermogenesis in Lean and ob/ob Mice , 2004 .

[14]  B. Cannon,et al.  Depressed thermogenesis but competent brown adipose tissue recruitment in mice devoid of all hormone-binding thyroid hormone receptors. , 2004, Molecular endocrinology.

[15]  P. Trayhurn Thermoregulation in the diabetic-obese (db/db) mouse , 1979, Pflügers Archiv.

[16]  Y. Deshaies,et al.  Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice. , 2004, Endocrinology.

[17]  Jan Nedergaard,et al.  Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.

[18]  J. Granneman,et al.  White adipose tissue contributes to UCP1-independent thermogenesis. , 2003, American journal of physiology. Endocrinology and metabolism.

[19]  B. Lowell,et al.  β-Adrenergic Receptors, Diet-induced Thermogenesis, and Obesity* , 2003, Journal of Biological Chemistry.

[20]  M. Rossmeisl,et al.  Paradoxical resistance to diet-induced obesity in UCP1-deficient mice. , 2003, The Journal of clinical investigation.

[21]  B. Cannon,et al.  Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[22]  Bruce M. Spiegelman,et al.  Obesity and the Regulation of Energy Balance , 2001, Cell.

[23]  J. Ju,et al.  Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice , 2000, Nature Medicine.

[24]  L. Aronne,et al.  The effects of drugs used to treat obesity on the autonomic nervous system. , 2000, Obesity research.

[25]  A. Astrup,et al.  The sympathetic nervous system and obesity: role in aetiology and treatment , 2000, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[26]  Bruce M. Spiegelman,et al.  Towards a molecular understanding of adaptive thermogenesis , 2000, Nature.

[27]  G. Bray,et al.  The MONA LISA hypothesis in the time of leptin. , 1998, Recent progress in hormone research.

[28]  Hitoshi Yamashita,et al.  Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese , 1997, nature.

[29]  R. Surwit,et al.  Role of leptin in fat regulation , 1996, Nature.

[30]  L. Janský Humoral thermogenesis and its role in maintaining energy balance. , 1995, Physiological reviews.

[31]  B. Block,et al.  Thermogenesis in muscle. , 1994, Annual review of physiology.

[32]  Michael J. Stock,et al.  A role for brown adipose tissue in diet-induced thermogenesis , 1979, Nature.

[33]  M. Barrand,et al.  Reduced thermogenesis in obesity , 1979, Nature.